Effects of Vestibular Rehabilitation Interventions in the Elderly with Chronic Unilateral Vestibular Hypofunction
Arash
Bayat
Musculoskletal Rehabilitation Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
author
Nader
Saki
Hearing Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
author
text
article
2017
eng
Introduction: Although vestibular rehabilitation therapy (VRT) methods are relatively popular in treating patients with body balance deficits of vestibular origin, only limited studies have been conducted into customized exercises for unilateral vestibular hypofunction (UVH). Furthermore, very little evidence is available on the outcomes of VRT in the elderly population with chronic UVH. Materials and Methods: A total of 21 patients, aged 61 to 74 years, with UVH participated in this study. The dizziness handicap inventory (DHI) was performed immediately before, and 2 and 8 weeks after treatment. Results: All patients showed a reduction in DHI scores during the study. The average decrease in DHI score was 25.98 points after 2 weeks’ intervention (P<0.001) and 32.54 points at the end of the study. This improvement was observed in all DHI subscores, and was most profound in the functional aspect. The correlation between the degree of final recovery and canal paresis was not significant (P>0.05). There were no relationships between the scores and gender. Conclusion: Our study demonstrates that VRT is an effective method for the management of elderly patients with UVH, and shows maximal effect on functional aspects.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
29
v.
4
no.
2017
183
188
https://ijorl.mums.ac.ir/article_8912_cd41a35a4c00f05c30dac1e06fb1543f.pdf
dx.doi.org/10.22038/ijorl.2017.18825.1629
Maternal Risk Factors Associated with the Development of Cleft Lip and Cleft Palate in Mexico: A Case-Control Study
Emmanuel
Angulo-Castro
Department of Perinatology, The Women's Hospital, Secretariat of Health, 80127, Culiacan, Sinaloa, Mexico.
author
Luis F
Acosta-Alfaro
Department of Perinatology, The Women's Hospital, Secretariat of Health, 80127, Culiacan, Sinaloa, Mexico.
author
Alma
Guadron-Llanos
CIASaP, School of Medicine, Autonomous University of Sinaloa, 80246, Culiacan, Sinaloa, Mexico
author
Adrian
Canizalez-Roman
Research Department, The Women's Hospital, Secretariat of Health, 80127, Culiacan, Sinaloa, Mexico
author
Fernando
Gonzalez-Ibarra
Department of Internal Medicine, Gulf Coast Medical Center, Panama City, 32405, Florida, USA.
author
Ignacio
Osuna-Ramirez
Faculty of Biological and Chemical Sciences, Autonomous University of Sinaloa, 80000 Culiacán, SIN, Mexico.
author
Joel
Murillo-LLanes
Research Department, The Women's Hospital, Secretariat of Health, 80127, Culiacan, Sinaloa, Mexico
author
text
article
2017
eng
Introduction: Cleft lip and palate, the most common developmental deformity, is seen worldwide and the etiology involves a combination of genetic and environmental factors. The purpose of this study was to determine the maternal risk factors associated with the development of cleft lip and cleft palate. Materials and Methods: We conducted a case control study at the Women’s Hospital in Culiacan, Mexico. Medical records were analyzed, including patients who delivered babies with and without cleft lip and cleft palate from January 2010 to December 2015. Multiple variables were analyzed, including gestational age, weight at birth, the use of folic acid and multivitamins during pregnancy, smoking, alcohol abuse, the use of recreational drugs, history of sexually transmitted infections, marital status, socioeconomic status, education, and nutritional status. Results: We found that the maternal risk factors with the strongest association for the development of cleft lip and cleft palate were the following: patients who were not taking folic acid during pregnancy [OR 3.27, 95% CI 1.32-8.09], P=0.00; patients who were not taking vitamin supplementation during pregnancy [OR 2.6, 95% CI 1.19-7.27], P=0.02; smoking during pregnancy [OR 2.05, 95% CI 1.23-3.41], P=0.01; and alcohol abuse during pregnancy [OR 1.90, 95% CI 1.17-3.08], P=0.03. Conclusions: The main risk factors associated with the development of cleft lip and cleft palate in a Mexican population at the Women’s hospital in Culiacan, Sinaloa, Mexico were smoking, alcohol abuse, and patients not taking folic acid and multivitamins during pregnancy.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
29
v.
4
no.
2017
189
195
https://ijorl.mums.ac.ir/article_8925_013f38bfd0021840f218f233ca8a056f.pdf
dx.doi.org/10.22038/ijorl.2017.19302.1650
The Antioxidant Effect of Curcumin on Cochlear Fibroblasts in Rat Models of Diabetes Mellitus
Tengku- Siti- Hajar
Haryuna
Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universitas Sumatera Utara, Medan 20155, Indonesia
author
Delfitri
Munir
Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universitas Sumatera Utara, Medan 20155, Indonesia
author
Ana
Maria
Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universitas Sumatera Utara, Medan 20155, Indonesia
author
Jenny
Bashiruddin
Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta 10430, Indonesia
author
text
article
2017
eng
Introduction: The aim of this study was to investigate the potential of curcumin as an antioxidant to increase the expression of superoxide dismutase (SOD) in fibroblasts of the cochlear lateral wall in rat models of diabetes mellitus. Materials and Methods: Twenty-four male Wistar rats Rattus norvegicus were randomly divided into six groups: group 1 as the control group; group 2 as the diabetic group; group 3 and 4 as the diabetic groups that received curcumin therapy of 200 and 400 mg/kg b.w. for 3 days, respectively; and group 5 and 6 as the diabetic groups that received curcumin therapy of 200 and 400 mg/kg b.w. for 8 days, respectively. All rats underwent termination and necropsy procedure on their temporal bones for immunohistochemical assay to determine the expression of SOD. Results: The decreased expression of SOD was detected in the diabetic group (without curcumin treatment). The treatment of curcumin at doses of 200 and 400 mg/kg b.w. for 3 and 8 days led to significant differences (P<0.05) in the expression of the SOD compared to diabetic group (without curcumin treatment). No significant differences were found in terms of dose and duration of curcumin administration on the expression of SOD. Conclusion: Curcumin may act as an antioxidant against oxidative stress due to diabetes mellitus via increased expression of SOD on cochlear fibroblasts in rat models of diabetes mellitus.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
29
v.
4
no.
2017
197
202
https://ijorl.mums.ac.ir/article_8926_2b2262b7b701928acc0c18fab107fa1a.pdf
dx.doi.org/10.22038/ijorl.2017.19603.1660
Serum Levels of Cyfra 21 in Patients with Benign and Malignant Salivary Gland Tumors
Naghmeh
Jeiroodi
Department of Oral and Maxillofacial Pathology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
author
Seyed Mohammad- Javad
Aslani
Student Research Committee, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
author
Bijan
Khademi
Otolaryngology Research Center, Department of Otolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran.
author
Mahyar
Malekzadeh
Institute of Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
author
Zohreh
Jaafari- Ashkavandi
Department of Oral and Maxillofacial Pathology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
author
text
article
2017
eng
Introduction: Cyfra 21 is a serum-soluble fragment of cytokeratin19. Increased Cyfra 21 serum levels and their benefit as a tumor marker have been shown in some malignancies. This study aimed to evaluate the serum levels of Cyfra 21 in patients with benign and malignant salivary gland tumors. Materials and Methods: In this cross-sectional study, the serum level of Cyfra 21 in 44 patients with malignant salivary gland tumors and 16 cases of pleomorphic adenoma were compared with 28 healthy controls using enzyme-linked immunosorbent assay (ELISA). Data were analyzed statistically using the Kruskal Wallis test, analysis of variance (ANOVA) and Spearman’s correlation tests. Results: Mean serum levels of Cyfra 21 were 0.135 ± 0.285 ng/ ml in the control group, 0.167 ± 0.142 ng/ ml in patients with pleomorphic adenoma and 1.059 ± 3.251 ng/ml in patients with malignant salivary gland tumors. There was no significant difference among groups. Cyfra 21 levels did not correlate with location of tumor, clinical stage or cigarette smoking. Conclusion: Results of the present study showed no significant difference in Cyfra 21 serum level in salivary gland tumors compared with normal individuals. In addition, Cyfra 21 serum level was not sufficiently sensitive to function as a tumor marker in salivary gland tumors.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
29
v.
4
no.
2017
203
208
https://ijorl.mums.ac.ir/article_8946_9adc07bf5e867394f0862d3701dfd7da.pdf
dx.doi.org/10.22038/ijorl.2017.21085.1699
Is the Persian Version of the “Olfactory Disorder Questionnaire” Reliable and Valid?
Maryam
Jalessi
Skull Base Research Center, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences (IUMS ), Tehran, Iran.
author
Seyed Kamran
Kamrava
ENT and Head & Neck Research Center, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences (IUMS ), Tehran, Iran.
author
Elahe
Amini
ENT and Head & Neck Research Center, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences (IUMS ), Tehran, Iran.
author
Farhad
Rafiei
ENT and Head & Neck Research Center, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences (IUMS ), Tehran, Iran.
author
Mohammad Amin
Nasouti
Skull Base Research Center, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences (IUMS ), Tehran, Iran.
author
Naeimeh
Moosavi
Skull Base Research Center, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences (IUMS ), Tehran, Iran.
author
Mohammad
Farhadi
ENT and Head & Neck Research Center, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences (IUMS ), Tehran, Iran.
author
text
article
2017
eng
Introduction: The Questionnaire for Olfactory Dysfunction (QOD) is a self-reporting olfactory-related quality of life questionnaire. The aim of this study was to determine the reliability and validity of the Persian version of this questionnaire. Materials and Methods: One hundred and thirteen patients with olfactory problems were enrolled in this study. The English version of the QOD was first translated into Persian. The reliability was then tested by determining the Cronbach alpha coefficient to assess internal consistency. The QOD was reviewed by a panel of experts, followed by calculating the content validity index to determine the content validity. Results: Based on the reliability analysis, the total Cronbach alpha was 0.88. The items in the “life quality” and “parosmia” domains had a good internal consistency in total, as well as in both genders and in different age subgroups. For the “sincerity” domain, however, low internal consistency was revealed (Cronbach alpha = 0.25). When questions related to the sincerity domain were omitted, the Cronbach alpha reached 0.89. The overall scale validity index for clarity and relevance were 0.88 and 0.87, respectively. Conclusion: The Persian version of the QOD seems to be a reliable and valid tool for the assessment of quality of life in patients with olfactory dysfunction. The “sincerity” domain cannot be used separately or should be substantially modified in order to be applicable to the Iranian population. However, there is no need to change the whole format of the questionnaire.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
29
v.
4
no.
2017
209
213
https://ijorl.mums.ac.ir/article_8942_911486c7f6f6af8d09d2e900e01322a1.pdf
dx.doi.org/10.22038/ijorl.2017.22436.1739
Fishbones in the Upper Aerodigestive Tract: A Review of 24 Cases of Adult Patients
Stanislas
Ballivet- de -Regloix
Department of ENT – Head and Neck Surgery, Military Training Hospital Percy,101, Avenue Henri Barbusse
92140, Clamart, France.
author
Anna
Crambert
Department of ENT – Head and Neck Surgery, Military Training Hospital Percy,101, Avenue Henri Barbusse
92140, Clamart, France.
author
Olga
Maurin
Emergency Department, Fire Fighting Brigade of Paris, Place Jules Renard 75017, Paris, France.
author
Gratien
Bonfort
Department of ENT – Head and Neck Surgery, Military Training Hospital Percy,101, Avenue Henri Barbusse
92140, Clamart, France.
author
Salome
Marty
Department of ENT – Head and Neck Surgery, Military Training Hospital Percy,101, Avenue Henri Barbusse
92140, Clamart, France.
author
Yoann
Pons
Department of ENT – Head and Neck Surgery, Military Training Hospital Percy,101, Avenue Henri Barbusse
92140, Clamart, France.
author
text
article
2017
eng
Introduction:
We present a retrospective study series and discussion of the current literature to discuss the management of fishbones in the upper aerodigestive tract.
Materials and Methods:
From January 2013 to July 2016, all patients referred to our referral center because of a fishbone in the upper aerodigestive tract were analysed.
Results:
Of the 24 patients, 95% of them reported discomfort in the throat. It was noted that 58% of physical examinations and nasofibroscopy results were normal. Ten fishbones were found in the upper aerodigestive tract. They were removed by foreign body forceps or by endoscopy depending on the location. Foreign body-related complications were not observed. Ten patients with no identifiable fishbone had no symptoms after 48 hours. Other patients, including the 10 patients with the fishbone removed, were asymptomatic after 10 days.
Conclusion:
From our experience, we recommend a systematic nasofibroscopy. If it is normal, the patient is assessed at 48h. The complementary investigation by CT scan and/or oesophagoscopy must be reserved in cases of suspicion of oesophageal localization or complication. Otherwise, rigid or flexible endoscopy may be performed when laryngoscopy is unsuccessful or for the treatment of foreign bodies lodged below this area.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
29
v.
4
no.
2017
215
219
https://ijorl.mums.ac.ir/article_9056_b9980503bd4714baa4179bdc3fd1dd66.pdf
dx.doi.org/10.22038/ijorl.2017.21440.1718
An Unusual Cause of Postaural Swelling: Kimura’s Disease
Purodha
Prasad
Department of Otorhinolaryngology, Maulana Azad Medical College, New Delhi, India.
author
Swati
Tandon
Department of Otorhinolaryngology, Maulana Azad Medical College, New Delhi, India.
author
Vasun
Batra
Department of Otorhinolaryngology, Maulana Azad Medical College, New Delhi, India.
author
Ishwar
Singh
Department of Otorhinolaryngology, Maulana Azad Medical College, New Delhi, India.
author
text
article
2017
eng
Introduction: Kimura’s disease (KD) is an allergic inflammatory disorder of unknown etiology endemic in Orientals. Kimura’s disease was first mentioned by Kimm and Szeto in China in 1937. Kimura’s disease is commonly encountered in Asia and is mostly reported in Japan, China, Singapore and Honkong. However, only a few cases have been reported in the Indian subcontinent. Case Report: A case of Kimura’s disease in a young male managed by surgery is reported in addition to a literature review. Conclusion: Diagnosis is made on the basis of histopathological analysis, clinical presentation, and laboratory investigations. Long term follow-up is required as Kimura’s disease is prone for recurrence.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
29
v.
4
no.
2017
221
224
https://ijorl.mums.ac.ir/article_8930_04fe6826a01a8ed24d664976e48e027c.pdf
dx.doi.org/10.22038/ijorl.2017.8930
Mixed Pyolaryngocele: A Rare Case of Deep Neck Infection
Rachid
Mahdoufi
Department of Otorhinolaryngology-Head and Neck Surgery, Service d’ORL-CCF, Hospital 20 Aout 1953, CHU IBN ROCHD, Casablanca, Maroc.
author
Ismail
Barhmi
Department of Otorhinolaryngology-Head and Neck Surgery, Service d’ORL-CCF, Hospital 20 Aout 1953, CHU IBN ROCHD, Casablanca, Maroc.
author
Nabil
Tazi
Department of Otorhinolaryngology-Head and Neck Surgery, Service d’ORL-CCF, Hospital 20 Aout 1953, CHU IBN ROCHD, Casablanca, Maroc.
author
Redallah
Abada
Department of Otorhinolaryngology-Head and Neck Surgery, Service d’ORL-CCF, Hospital 20 Aout 1953, CHU IBN ROCHD, Casablanca, Maroc.
author
Mohamed
Roubal
Department of Otorhinolaryngology-Head and Neck Surgery, Service d’ORL-CCF, Hospital 20 Aout 1953, CHU IBN ROCHD, Casablanca, Maroc.
author
Mohamed
Mahtar
Department of Otorhinolaryngology-Head and Neck Surgery, Service d’ORL-CCF, Hospital 20 Aout 1953, CHU IBN ROCHD, Casablanca, Maroc.
author
text
article
2017
eng
Introduction: Pyolaryngocele is a very rare and serious complication of laryngocele. It can present as deep neck space infection and mislead the diagnosis. Our aim is to bring this unusual entity to the attention of surgeons and describe its clinical features. Case Report: We report a case of a 45-year-old male patient with a five-week history of neck swelling, dysphonia, dyspnea and odynophagia. An urgent CT scan showed a mixed pyolaryngocele. The management consisted of a high dose antibiotic and an excision of the residual laryngocele via an external approach. Conclusion: A pyolaryngocele is an unusual complication of laryngocele, which becomes secondarily infected, causing many symptoms. Removing the laryngocele is still the best treatment option to prevent this complication and recurrence.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
29
v.
4
no.
2017
225
228
https://ijorl.mums.ac.ir/article_8931_5f853555e39c8c7aead105b56f68f77f.pdf
dx.doi.org/10.22038/ijorl.2017.8931
Pharyngocutaneous Fistula as a Rare Late Postoperative Complication Following Submandibulectomy: A Case Report
Leila
Mashali
Department of Otolaryngology Head and Neck Surgery, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
author
Somayeh
Araghi
Department of Otolaryngology Head and Neck Surgery, Tehran University of Medical Sciences, Tehran , Iran.
author
text
article
2017
eng
Introduction: Submandibular gland excision is the gold standard treatment for submandibular gland disease. Although submandibulectomy is a relatively standardized surgical procedure, complications are frequently reported. These complications include nerve paralysis or paresis, aesthetic sequelae, hematoma, salivary fistulas or sialoceles, wound infections, hypertrophic scars and inflammations caused by residual lithiasis in the salivary duct. Case Report: We report a case of a rare complication of submandibular gland excision, pharyngocutaneous fistula, which appeared 6 years after previous surgery. The patient underwent surgery, during which a fistula tract from the skin to the pharynx was found and excised. Conclusion: The authors believe that inappropriate execution of the surgical procedure could result in postoperative complications.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
29
v.
4
no.
2017
229
231
https://ijorl.mums.ac.ir/article_8971_2ea35c28d232979bdc03a1fe2a12b4cc.pdf
dx.doi.org/10.22038/ijorl.2016.14532.1519
Diffuse Idiopathic Skeletal Hyperostosis Involving Cervical and Lumbar Spine Presenting with Dysphagia: A Case Report
Ramanuj
Sinha
Department of Otorhinolaryngology, Medical College, Kolkata, India.
author
Neeraj
Aggarwal
Department of Otorhinolaryngology, Medical College, Kolkata, India.
author
Sirshak
Dutta
Department of Otorhinolaryngology, Medical College, Kolkata, India.
author
Avijit
Choudhury
Department of Otorhinolaryngology, Medical College, Kolkata, India.
author
Sanjoy-Kumar
Ghosh
Department of Otorhinolaryngology, Medical College, Kolkata, India.
author
Debasis
Guha
Senior Divisional Medical Officer, B R Singh Hospital (Eastern Railways), Kolkata, India
author
text
article
2017
eng
Introduction: Diffuse Idiopathic Skeletal Hyperostosis (DISH) is a very rare cause of dysphagia when it occurs in the cervical spine. It can also affect the lumbar region where it causes deformity. Case Report: In this article, a rare case of Diffuse Idiopathic Skeletal Hyperostosis involving both the cervical and lumbar spine, presenting with dysphagia and spinal stiffness leading to a stooping posture, is reported. Conclusion: Cases of simultaneous involvement of cervical and lumbar vertebrae by Diffuse Idiopathic Skeletal Hyperostosis, presenting with symptoms of both area involvement, are rarely reported in the English literature. When investigating a case of dysphagia, a high level of suspicion is required to diagnose such a condition.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
29
v.
4
no.
2017
233
236
https://ijorl.mums.ac.ir/article_8972_6fbc4155638bcfc9c6d0621e730f0cc6.pdf
dx.doi.org/10.22038/ijorl.2017.8972