@article { author = {Ahmadi, Mohammad Saeed and Amirhassani, Shahriar and Poorolajal, Jalal}, title = {The Effect of Adenotonsillectomy on Pediatric Nocturnal Enuresis: a Prospective Cohort Study}, journal = {Iranian Journal of Otorhinolaryngology}, volume = {25}, number = {1}, pages = {37-40}, year = {2013}, publisher = {Mashhad University of Medical Sciences (MUMS)}, issn = {2251-7251}, eissn = {2251-726X}, doi = {10.22038/ijorl.2012.65}, abstract = {Introduction: Sleep disorder caused by adenotonsillar hypertrophy has been implicated as a cause of primary and secondary nocturnal enuresis in children.  This study was conducted to investigate the effect of adenotonsillectomy on enuresis in children with adenotonsillar hypertrophy.  Materials and Methods: This prospective cohort study was conducted in Hamadan City in Western Iran, from April 2010 to December 2011. Ninety-seven children aged 3 to 12 years with adenotonsillar hypertrophy who were admitted to Besat Hospital for adenotonsillectomy were evaluated. The primary outcome was the number of incidents of bedwetting (nocturnal enuresis) post-operation compared with pre-operation. Patients were followed-up for 3 months. Data were collected using a questionnaire regarding number of bedwetting incidents, type of enuresis (primary or secondary), and family history of enuresis, as well as results of urine analysis.  Results: Of 420 children admitted for adenotonsillectomy, 97 had a positive history of preoperative enuresis, including 42 girls and 55 boys, with mean age of 48 months. The parents of 84 (86.6%) children agreed to participate in the study. Three months after adenotonsillectomy, enuresis had resolved completely in 51 (60.7%) children and had shown relative improvement in 22 (26.2%) children. Enuresis had not improved in the remaining 11 (13.1%) children (P<0.001).  Conclusion:  The results of this study indicate that adenotonsillectomy can improve enuresis in the majority of children with adenotonsillar hypertrophy. However, further evidence based on large multi-center randomized clinical trials is required to confirm these results.}, keywords = {Adenoids,Hypertrophy, Cohort studies,Enuresis, Iran}, url = {https://ijorl.mums.ac.ir/article_65.html}, eprint = {https://ijorl.mums.ac.ir/article_65_8c647b5eec717f36fc2c07f18c481a08.pdf} }