eng
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
2011-01-01
23
1
1
10
10.22038/ijorl.2011.613
613
Acoustic Neurinomas
Mohammad Faraji Rad
1
Department of neurosurgery, Mashhad university of Medical Sciences, Mashhad, Iran
Acoustic neuromas (AN) are schwann cell-derived tumors that commonly arise from the vestibular portion of the eighth cranial nerve also known as vestibular schwannoma(VS) causes unilateral hearing loss, tinnitus, vertigo and unsteadiness. In many cases, the tumor size may remain unchanged for many years following diagnosis, which is typically made by MRI. In the majority of cases the tumor is small, leaving the clinician and patient with the options of either serial scanning or active treatment by gamma knife radiosurgery (GKR) or microneurosurgery. Despite the vast number of published treatment reports, comparative studies are few. The predominant clinical endpoints of AN treatment include tumor control, facial nerve function and hearing preservation. Less focus has been put on symptom relief and health-related quality of life (QOL). It is uncertain if treating a small tumor leaves the patient with a better chance of obtaining relief from future hearing loss, vertigo or tinnitus than by observing it without treatment. In this paper we review the literature for the natural course, the treatment alternatives and the results of AN. Finally, we present our experience with a management strategy applied for more than 30 years.
https://ijorl.mums.ac.ir/article_613_806dbf3e8e29ff6010815c60d1511f1c.pdf
Acoustic neuromas
Acoustic schwannoma
brain tumor
Vestibular schwannoma
Vestibular neurilemmomas
eng
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
2011-01-01
23
1
11
22
10.22038/ijorl.2011.616
616
Original
Repair of Head and Face Defects with the Use of Pericranial Flap
Mohammad Naeimi
1
Saeed Hosseini
2
Ear, Nose, Throat, Head and Neck surgery Research Center,Mashhad University of Medical Sciences, Mashhad, Iran
Department of otorhinolaryngology, Mashhad University of Medical Sciences, Mashhad, Iran
Introduction:
The pericranial flaps' benefits have been described in many otolaryngologic, maxillofacial and plastic surgery literature. The benefits ar e due to the pericranial flaps unique characteristics including good flexibility and mobility, very rich blood supply from several arterial sources and access to sufficient bulk of the flap without any need for distant surgical sites. Using pericranial flaps to repair the local defects of the head and face region in several cases has been reported in this study.
Materials and Methods:
A follow up study was carried out on 12 patients who had undergone frontal sinus obliteration; auriculoplasty and repair of the orbital walls and scalp’s defects. Pericranial flap had been used for all these patients. Demographic specifications, surgical indications, imaging evaluations and early and late complications were recorded as well. The functional and cosmetic results and also the satisfaction level of patients were also assessed.
Results:
According to the average follow up period which lasted about 4 years, none of the patients suffered early or late significant complications. No disease relapse or need for revision surgery was reported. Almost all patients were completely satisfied with the procedure and its cosmetic results.
Conclusion:
The use of a pericranial flap is a simple, quick, cost-effective and safe method for repair of head and face defects. Although, a longer follow up time is required, but this uncomplicated method has been considered as an ideal method to repair sinonasal, ear and scalp defects.
https://ijorl.mums.ac.ir/article_616_132f46a992d8398ebdb9770bf9f7b4d7.pdf
Face
Head
Neck
Surgical flap
eng
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
2011-01-01
23
1
23
28
10.22038/ijorl.2011.618
618
Normal Saline Versus Hypertonic 3% Saline: It’s Efficacy in Non-Acute Rhinosinusitis
Nezamoddin Berjis
berjis@med.mui.ac.ir
1
Seyyed Mehdi Sonbolastan
2
Seyyed Hanif Okhovat
3
Ali Asghar Narimani
4
Jaleh Razmjui Razmjui
5
Department of otorhinolaryngology, Isfahan University of Medical Sciences, Isfahan, Iran
Department of otorhinolaryngology, Isfahan University of Medical Sciences, Isfahan, Iran
Department of otorhinolaryngology, Isfahan University of Medical Sciences, Isfahan, Iran
Department of otorhinolaryngology, Isfahan University of Medical Sciences, Isfahan, Iran
General physician, Isfahan University of Medical Sciences, Isfahan, Iran
Introduction:
Sinusitis is one of the most common diseases in general and in otolaryngology practice, but the optimal therapeutic options have not yet been fully developed. This manuscript will try to compare normal saline nasal douching with hypertonic saline in reducing symptoms and improving its signs.
Materials and Methods:
One hundred and fourteen patients suffering from non acute rhinosinusitis, documented by history, physical examination and radiologic studies were divided into normal saline and hypertonic saline groups, each consisting of 57 patients. data were obtained by physical examination and a questionnaire..
Results:
Type of treatment had no significant effect on headache, morning dryness of mouth and pharynx and fatigue. Nontheless, nasal congestion, purulent discharge and postnasal discharge were reported to have improved in the group treated with hypertonic saline versus the normal saline group. Patient satisfaction also showed better scores in the hypertonic saline group.
Conclusion:
Hypertonic saline (3%) is more effective for nasal irrigation than normal saline in chronic rhinosinusitis.
https://ijorl.mums.ac.ir/article_618_3e6f799a357bc3297cfb677aaf538a61.pdf
Chronic Rhinosinusitis
Hypertonic saline
Postnasal discharge
eng
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
2011-01-01
23
1
29
36
10.22038/ijorl.2011.623
623
Original
Interleukin-8-251 A/T and CXCR2 +1208 C/T Genes Polymorphisms in Chronic Rhinosinusitis
Bijan Khademi
khademib@sums.ac.ir
1
Seyed Hossein Dastgheib
2
Eskandar Kamali-Sarvestani
3
Department of otorhinolaryngology, Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz,Iran
Department of otorhinolaryngology, Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, Iran
Department of immunology, Shiraz University of Medical Sciences, Shiraz, Iran
Introduction:
IL-8 is one of the pro-inflammatory cytokines which can play an essential role in the pathogenesis of chronic rhinosinusitis (CRS) as well as nasal polyposis (NP). The ability of individuals in producing IL-8 is partially determined by IL-8-251 A/T polymorphism. Hence, the aim of the present study was to investigate the association between IL-8-251 A/T and CXCR2 +1208 C/T genes polymorphisms and susceptibility to CRS and NP.
Materials and Methods:
Two hundred and forty fiveCRS patients and 204 healthy controls were included in this study. CRS patients were categorized by the existence or absence of NP. IL-8 promoter-251 A/T and CXCR2 +1208 C/T gene polymorphisms were genotyped via the allele specific PCR (AS-PCR) method.
Results:
While no remarkable difference was demonstrated between patients and controls for both CXCR2 +1208 C/T and IL-8 -251 A/T polymorphisms, a significant increase in IL-8-251 AA genotype was detected in CRS patients with NP compared to those without it (29.3% and 16.2%, respectively; P=0.03). Interestingly, this association got far stronger when only non-asthmatic CRS patients were taken into consideration (P=0.001).
Conclusion:
The results of the present study indicate that the inheritance of IL-8-251 Aallele is associated significantly with NP development in CRS patients. Therefore, NP formation might be a result of the exposure to an intense inflammatory environment, which is more likely in genetically susceptible CRS patients.
https://ijorl.mums.ac.ir/article_623_c941af1cc1254b2ae1ca213e399e21e0.pdf
Chronic Rhinosinusitis
CXCR2
InterleukinL-8
Nasal polyposis
Polymorphism
eng
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
2011-01-01
23
1
37
44
10.22038/ijorl.2011.624
624
Original
Otoacoustic Emissions in Sudden Sensorineural Hearing Loss: Changes of Measures with Treatment
Shadman Nemati
drshadmannemati_ent@yahoo.com
1
Seyyed-Ebrahim Naghavi
2
Ehsan Kazemnejad
3
Roozbeh Banan
4
Department of otorhinolaryngology, Guilan University of Medical Sciences, Rasht, Iran
Department of otorhinolaryngology, Guilan University of Medical Sciences, Rasht, Iran
Department of biostatistics, Guilan University of Medical Sciences, Rasht, Iran
Ear, Nose, Throat, Head and Neck surgery Research Center, Guilan University of Medical Sciences, Rasht, Iran
Introduction:
To identify changes in OAEs parameters in treatment course of idiopathic sudden sensorineural hearing loss (iSSNHL).
Materials and Methods:
In aprospective studyfromAugust 2005 to January 2009, 26 patients with iSSNHL underwent conventional audiometry/tympanometry and two types of OAEs (TEOAEs and DPOAEs) before and after the completion of standard drug therapy.The changes in pre- and post- treatment parameters were compared with each other and with normal-contralateral ears.
Results:
In TEOAEs, the mean overall correlation (reproducibility) and the mean overall strength in involved ears were 10.96±23.36 and 0.99±3.45 dB, respectively, before the treatment, which reached 22.88±36.55 and 1.85±5.3, respectively, after the treatment (P>0.05). Significant difference between “correlation score” (average of correlations at 3-4 involved frequencies) before and after treatment was found: 6.52 ±18.19 vs. 21.67±37.8 (P<0.034). The difference between pre- and post-treatmentoverall correlation and correlation score in the “response group” were significant (P<0.031). In DPOAEs of the involved ears, the mean DP1 level and the DP1 signal-to-noiseratio changes were not significant with the treatment (P>0.05).
Conclusion:
Evoked OAEs, especially TEOAEs, are objective, rapid, and sensitive tools in the treatment course of iSSNHL.
https://ijorl.mums.ac.ir/article_624_ff0e9f1a0a318b6fcc826458730d2237.pdf
Idiopathic sudden sensorineural hearing loss
Otoacoustic emissions
response
Treatment
eng
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
2011-01-01
23
1
45
50
10.22038/ijorl.2011.627
627
Hypoglossal Schowannoma:
A Case Report and Review of Literature
Masoud Naghibzadeh
naghibzadehm@mums.ac.ir
1
Mohammad Faraji Rad
2
Shima Kamandi Kamandi
3
Ear, Nose, Throat, Head and Neck surgery Research Center,Mashhad University of Medical Sciences, Mashhad, Iran
2Department of neurosurgery, Mashhad University of Medical Sciences, Mashhad, Iran
Department of otorhinolaryngology, Mashhad University of Medical Sciences, Mashhad, Iran
Introduction:
Schawannomas (neuromas, neurilemmomas) are benign tumors originating from showann cells or nerve fiber sheet cells. They are solitary, encapsulated tumors usually attached to, or surrounded by a nerve.
Case Report:
We present a case of left hypoglossal nerve schwannoma in a 19 year old man who was admitted with progressive left tongue atrophy.
Conclusion:
Schwannoma of the hypoglossal nerve usually develops in the intracranial and extracranial portion or both in the intracranial and extracranial components forming a dumbbell shape tumor .The peripheral hypoglossal schwannomas are extremely rare.
https://ijorl.mums.ac.ir/article_627_ef0e09b1ed8bd2d052b1e86021d8b732.pdf
Hypogloss
Schawannomas
Tumur
eng
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
2011-01-01
23
1
51
54
10.22038/ijorl.2011.630
630
Ear Candling: A Dangerous Pleasure?
Kianoosh Nahid
kianooshnahid@gmail.com
1
Prepageran Narayanan
2
Mohammad Amin Jalaluddin
3
Department of otorhinolaryngology, Malaysia University of Medical Sciences, Kuala Lumpur, Malaysia
2Department of otorhinolaryngology, Malaysia University of Medical Sciences, Kuala Lumpur, Malaysia
Department of otorhinolaryngology, Malaysia University of Medical Sciences, Kuala Lumpur, Malaysia
Ear candling is an alternative medicine practice alleged to enhance general health by putting an end of a hollow candle in the ear canal and lighting up the other end of it. It also is advertised for cerumen and debris (bacteria and fungi) removal.
Ear candling is claimed to create negative pressure for drawing cerumen from the ear and to benefit the ears in many ways. It is however not free of complications and is now banned. Here we would like to highlight potential complications to this.
https://ijorl.mums.ac.ir/article_630_ef70b2783839a565c3a2f5024afd9477.pdf
Ear candling
Ear coning
Thermal auricular therapy
eng
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
2011-01-01
23
1
55
58
10.22038/ijorl.2011.632
632
A Giant Hemangioma of the Tongue
Babak Saedi
Saedi@tums.ac.ir
1
Asghar Hajipour
2
Mihan Jafari Javid
3
Department of otorhinolaryngology, Tehran University of Medical Sciences, Tehran, Iran
Department of anesthesiology, Tehran University of Medical Sciences, Tehran, Iran
Department of anesthesiology, Tehran University of Medical Sciences, Tehran, Iran
Introduction:
Vascular abnormalities are relatively uncommon lesions, but head and neck is a common region for vascular malformation which is classified as benign tumors. In this paper, the authors report a rare presentation of vascular malformation in the tongue and its managements.
Case Report:
An 18 months 2 old child presented with a giant mass of tongue which caused functional and aesthetic problem. The rapid growth pattern of cavernous hemangioma was refractory to corticosteroid. The lesion was excised without any complication. Since the mass was so huge that not only filled entire oral cavity but was protruding outside, airway management was a great challenge for anesthesia plan and at the same time surgical technique was difficult to select.
Conclusion:
Despite different recommended modalities in managing hemangiomas of the tongue, in cases of huge malformations, surgery could be the mainstay treatment and provided that critical care measures are taken in to account, could be performed very safely.
https://ijorl.mums.ac.ir/article_632_6dcb5347c7a5c2ccfc84d9504fb6ef96.pdf
Head and neck
Tongue
Tumor
Hemangioma
Vascular malformation