ORIGINAL_ARTICLE
The Relationship between the Behavioral Hearing Thresholds and Maximum Bilirubin Levels at Birth in Children with a History of Neonatal Hyperbilirubinemia
Introduction: Neonatal hyperbilirubinemia is one of the most important factors affecting the auditory system and can cause sensorineural hearing loss. This study investigated the relationship between behavioral hearing thresholds in children with a history of jaundice and the maximum level of bilirubin concentration in the blood. Materials and Methods: This study was performed on 18 children with a mean age of 5.6 years and with a history of neonatal hyperbilirubinemia. Behavioral hearing thresholds, transient evoked emissions and brainstem evoked responses were evaluated in all children. Results: Six children (33.3 %) had normal hearing thresholds and the remaining (66.7 %) had some degree of hearing loss. There was no significant relationship (r= -0.28, P= 0.09) between the mean total bilirubin levels and behavioral hearing thresholds in all samples. A transient evoked emission was seen only in children with normal hearing thresholds however in eight cases brainstem evoked responses had not detected. Conclusion: Increased blood levels of bilirubin at the neonatal period were potentially one of the causes of hearing loss. There was a lack of a direct relationship between neonatal bilirubin levels and the average hearing thresholds which emphasizes on the necessity of monitoring the various amounts of bilirubin levels.
https://ijorl.mums.ac.ir/article_658_8e780c3a3f09ee716c3e2b2f681a7760.pdf
2013-07-01
127
134
10.22038/ijorl.2013.658
Behavioral hearing threshold
Hearing Loss
Hyperbilirubinemia
Neonatal
Rasool
Panahi
1
Department of Audiology, Faculty of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Jafari
Zahra
z_ jafari@tums.ac.ir.
2
Department of Basic Sciences in Rehabilitation, Faculty of Rehabilitation, Rehabilitation Research Center, Tehran
AUTHOR
Sheibanizade
Abdoreza
3
Department of Audiology, Faculty of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Salehi
Masoud
4
Department of Biostatistics, Faculty of Management and Medical Information, University of Medical Sciences, Tehran, Iran.
AUTHOR
Esteghamati
Abdoreza
5
Children's Hospital, martyr Akbar-Abadi, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Hasani
Sara
6
Department of Audiology, Faculty of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
ORIGINAL_ARTICLE
Effects of Peritonsillar Injection of Tramadol and Adrenaline before Tonsillectomy;
Introduction: Various hemostatic and analgesic agents and techniques have been used to reduce intraoperative and postoperative hemorrhage and pain in tonsillectomy.Aims and objective; The current study aimed to compare the effect of using adrenaline plus tramadol and normal saline in maintaining hemostasis and control of pain in cold dissection tonsillectomy. Materials and Methods: This prospective randomized study was conducted over a period of 10 months in department of otorhinolaryngology state medical college Srinagar. In the current study 46 patients planed for tonsillectomy were put into two groups. 23 patients in each group. In group A patients (study group) 4ml of solution containing 1:200000 adrenaline and 2mg/kg tramadol was injected in peritonsillar space. In group B patients (control group) 4ml of normal saline was injected in peritonsillar space. Results: It was found that the time required to achieve heamostasis and post operative pain was less in group A patients in comparison to Group B patients. There was no significant side effect or complications when adrenaline and tramadol were used. Conclusion: Large randomized controlled studies are needed to compare tramadol plus adrenaline infiltration with other heamostatic and analgesics, but the current study indicated that Tramadol plus adrenaline infiltration could be an effective method to reduce the post operative pain , operative time and time to achieve heamostasis in tonsillectomy surgeries. Therefore the use of Tramadol plus adrenaline infiltration should be further promoted and implemented as routine use in tonsillectomy surgeries.
https://ijorl.mums.ac.ir/article_659_e358149e950d3c87273d949fa6db0735.pdf
2013-07-01
135
140
10.22038/ijorl.2013.659
epinephrine
Heamostasis
Pain
Tonsillectomy
Tramadol
Beigh
Zafarullah
beighzafarullah@yahoo.com.
1
Department of Otorhinolaryngology. Govt. Medical College Srinagar J&K India. Srinagar. India.
AUTHOR
ul Islam
Mudasir
2
Department of Otorhinolaryngology. Govt. Medical College Srinagar J&K India. Srinagar. India.
AUTHOR
Ahmad
Shakil
3
Department of Otorhinolaryngology. Govt. Medical College Srinagar J&K India. Srinagar. India.
AUTHOR
Pampori
Rafiq Ahmad
4
Department of Otorhinolaryngology. Govt. Medical College Srinagar J&K India. Srinagar. India.
AUTHOR
ORIGINAL_ARTICLE
Vestibular Evoked Myogenic Potential Produced by Bone-Conducted Stimuli: A Study on its Basics and Clinical Applications in Patients With Conductive and Sensorineural Hearing Loss and a Group With Vestibular Schawannoma
Introduction: Vestibular evoked myogenic potential (VEMP) has recently been broadly studied in vestibular disorders. As it is evoked by loud sound stimulation, even mild conductive hearing loss may affect VEMP results. Bone-conducted (BC) stimulus is an alternative stimulation for evoking this response. This study aims to assess the characteristics of BC-VEMP in different groups of patients. Materials and Methods: We performed a cross sectional analysis on 20 healthy volunteers with normal pure-tone audiometry as a control group; and on a group of patients consisted of 20 participants with conductive hearing loss, five with bilateral sensorineural hearing loss and four with vestibular schawannoma. AC and BC-VEMP were performed in all participants. Results: In control group the VEMP responses to both kinds of stimuli had an acceptable morphology and consisted of p13 and n23 waves. Latency value of these main components in each type of stimulus was not significantly different (P>0.05). However, the mean amplitude was larger in BC modality than AC stimulation (P=0.025). In the group with conductive hearing loss, the VEMP response was absent in fifteen (46.87%) of the 32 ears using the AC method, whereas all (100%) displayed positive elicitability of VEMP by BC method. Normal VEMP responses in both stimuli were evoked in all patients with sensorineural hearing loss. In patients with unilateral vestibular schwannomas (VS), 2 (50.00%) had neither AC-VEMP nor BC-VEMP. Conclusion: Auditory stimuli delivered by bone conduction can evoke VEMP response. These responses are of vestibular origin and can be used in vestibular evaluation of patients with conductive hearing loss.
https://ijorl.mums.ac.ir/article_657_f909665c763faa6592cc161bcd8bc8de.pdf
2013-07-01
141
146
10.22038/ijorl.2013.657
Bone Conduction
vestibular
VEMP
Parvane
Mahdi
parvanemahdi@yahoo.com
1
Department of Audiology, Faculty of Rehabilitation. Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Amin
Amali
a_amali@sina.tums.ac.ir
2
Department of Otorhinolaryngology-Head and Neck Surgery, Imam Khomeini Educational Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran.f Otorhinolaryngology-Head and Neck Surgery, Imam Khomeini Educational Complex Hospital,
AUTHOR
Akram
Pourbakht
3
Rehabilitation Research Center, Department of Audiology, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Alireza
Karimi Yazdi
4
Department of Otorhinolaryngology-Head and Neck Surgery, Imam Khomeini Educational Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Ali
Bassam
5
Department of Otorhinolaryngology-Head and Neck Surgery, Imam Khomeini Educational Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
ORIGINAL_ARTICLE
Endoscopic Cauterization of the Sphenopalatine Artery to Control Severe and Recurrent Posterior Epistaxis
Introduction: Epistaxis is one of the most common medical emergencies, making the management of posterior epistaxis a challenging problem for the ear, nose, and throat (ENT) surgeon. In the cases of conservative management failure, ligation of the major arteries or percutaneous embolization of the maxillary artery is performed routinely in most units, but rates of failure and complications are high.The objective of this study was to assess the effectiveness of endoscopic sphenopalatine artery (SPA) cauterization in patients with refractory posterior epistaxis. Materials and Methods: Between April 2011 and January 2012, 27 patients (15 males and 12 females) with refractory posterior epistaxis underwent endoscopic SPA cauterization in two tertiary referral hospitals in Shiraz. Three patients underwent bilateral cauterization. Results: Four patients (from 30 arteries) had new epistaxis after surgery, three experienced subsequent epistaxis requiring medical treatment, and one patient had a minor epistaxis not needing treatment. Conclusion: The SPA electrocoagulation technique seems to be safe, simple, fast, and effective with low rates of morbidity and complications for the management of refractory posterior epistaxis. Endoscopic SPA cauterization should be considered as an immediate second-line management when conservative treatment as first-line management fails.
https://ijorl.mums.ac.ir/article_662_7b38e010481b31c210b0582929956b6d.pdf
2013-07-01
147
152
10.22038/ijorl.2013.662
Epistaxis
Endoscopic sphenopalatine artery cauterization
SPA electrocoagulation technique
Behrooz
Gandomi
1
Department of Otorhinolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran.
AUTHOR
Mohammad Hosein
Arzaghi
2
Department of Otorhinolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran.
AUTHOR
Bijan
Khademi
khademib@sums.ac.ir
3
Department of Otorhinolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran.
AUTHOR
Mohammad
Rafatbakhsh
rafatm0@yahoo.com.
4
English Language Lecturer, Language Department, Shiraz University of Medical Sciences, Shiraz, Iran.
AUTHOR
ORIGINAL_ARTICLE
Middle Ear Exploration Results in Suspected Otosclerosis Cases Referred to Amir-Almomenin and Golsar Hospitals, Rasht, 2001-2011: Are Ossicular and Footplate Area Anomalies Rare?
Introduction: Otosclerosis is a disease of bony labyrinth. Structural changes in the labyrinth often cause ossicular fixation, and thus conductive hearing loss. The purpose of this study was to evaluate middle ear exploration findings and frequency of ossicular and footplate area anomalies in patients with suspected otosclerosis referred to Amiralmomenin and Golsar Hospitals in Rasht, Iran. Materials and Methods: In 47 patients undergone middle ear exploration in Amiralmomenin and Golsar hospitals from April 2001 to March 2011, the intraoperative findings, and other data were extracted from the medical records of the patients. The data was analyzed using SPSS 17 software. Results: Frequency of fixation of stapes, malleus, and incus by age and sex in patients undergoing middle ear exploration showed that stapes had been fixed in 39 patients, malleus in 6 patients, and incus in 21 patients. Analysis of data showed that there was no significant association between sex and age with fixation of any of ossicles (P>0/05). Middle ear anomalies were seen in 16 cases (34.0%). Overhanging of facial nerve in 4 cases, thick stapedial crura in 5 cases, and perilymph gusher in 2 cases were the most frequent anomalies. Conclusion: This study show that the results of middle ear explorations in our patients in the north of Iran is somehow different from the typical otosclerotic cases, although the frequency of ossicular anomalies is better to be evaluated and compared in different areas of Iran, and other countries.
https://ijorl.mums.ac.ir/article_660_8ce1682b1ca19947a1f79b6df4b86654.pdf
2013-07-01
155
159
10.22038/ijorl.2013.660
Anomalies
Incus
Malleus
Middle ear exploration
Otosclerosis
Ossicular fixation
Stapes
Shadman
Nemati
drshadmannemati_ent@yahoo.com
1
Otolaryngology-head and neck surgery Research Center, Amiralmomenin Hospital. Guilan University of Medical Sciences, Rasht, Iran.
AUTHOR
Ebrahim
Naghavi
2
Otolaryngology-head and neck surgery Research Center, Amiralmomenin Hospital. Guilan University of Medical Sciences, Rasht, Iran.
AUTHOR
Ehsan
Kazemnejad
3
Department of biostatistics, Faculty of Midwifery and Nursing, , Guilan University of Medical Sciences, Rasht, Iran.
AUTHOR
Mohammad
Aghajanpour
smaghajanpour@yahoo.com
4
Department of Otolaryngology-head and neck surgery, Guilan University of Medical Sciences, Rasht, Iran.
AUTHOR
Omid
Abdollahi
5
Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
AUTHOR
ORIGINAL_ARTICLE
Soluble HER-2 in Patients with Head and Neck Squamous Cell Carcinoma
Introduction:
The presence of HER-2 has been shown to be a prognostic factor in many kinds of cancers, but its role in head and neck squamous cell carcinoma (HNSCC) is not still defined. The purpose of the current study is to investigate the role of HER-2 in HNSCC and its correlation with various clinicopathologic parameters.
Materials and Methods:
Peripheral blood samples were obtained from 17 healthy volunteers and 69 patients with HNSCC before curative surgery. The HER-2 level was determined in each sample by sandwich ELISA. Statistical analysis was performed using an independent t-test, one-way ANOVA, and Mann-Whitney Test.
Results:
Mean HER-2 serum levels in patients with HNSCC compared with healthy controls was not statistically significant (3.85ng/ml vs. 3.75ng/ml; P>0.05). The mean serum level of HER-2 was higher in patients with lymph node involvement, metastasis, invasion, tumor size ≥2 cm, and stage>1, although the differences were not statistically significant (P>0.05).
Discussion:
Mean HER-2 serum levels in patients with tumor size T3 and higher were greater than those from patients in stage T1 and T2, a finding which may be translated into disease progression, growth and invasiveness.
Conclusion:
In this study the mean HER-2 serum level in patients with HNSCC was found statistically insignificant compared with the healthy control group. The role of soluble HER-2 as a tumor marker is still controversial and needs further studies to clarify its clinical relevance for early detection or screening for HNSCC.
https://ijorl.mums.ac.ir/article_663_c845de95e638c110cf704955f8680ee5.pdf
2013-07-01
161
167
10.22038/ijorl.2013.663
HNSCC
Her-2
EGFR
Tmor marker
Bijan
Khademi
khademib@sums.ac.ir
1
Department of Otorhinolaryngology, Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, Iran.
LEAD_AUTHOR
Behzad
Khademi
2
Department of Ophthalmology, Shiraz University of Medical Sciences, Shiraz, Iran.
AUTHOR
Abbas
Ghaderi
3
Department of Immunology, Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, Iran.
AUTHOR
Seyd Fakhroddin
Hosseini
4
Department of Otorhinolaryngology, Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, Iran.
AUTHOR
Nika
Niknejad
5
Department of Otorhinolaryngology, Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, Iran.
AUTHOR
ORIGINAL_ARTICLE
Auditory Memory deficit in Elderly People with Hearing Loss
Introduction: Hearing loss is one of the most common problems in elderly people. Functional side effects of hearing loss are various. Due to the fact that hearing loss is the common impairment in elderly people; the importance of its possible effects on auditory memory is undeniable. This study aims to focus on the hearing loss effects on auditory memory. Materials and Methods: Dichotic Auditory Memory Test (DVMT) was performed on 47 elderly people, aged 60 to 80; that were divided in two groups, the first group consisted of elderly people with hearing range of 24 normal and the second one consisted of 23 elderly people with bilateral symmetrical ranged from mild to moderate Sensorineural hearing loss in the high frequency due to aging in both genders. Results: Significant difference was observed in DVMT between elderly people with normal hearing and those with hearing loss (P<0.22). According to the correlation test between Pure Tone Average (PTA) and the mean score of DVMT, increasing PTA resulted in reduction of DVMT score and this result was seen in both genders and all of the studied subjects. Conclusion: Apart from aging, age-related hearing loss has shown significant effect on auditory verbal memory. This result depicts the importance of auditory intervention to make better communicational skills and therefore auditory memory in this population.
https://ijorl.mums.ac.ir/article_661_4b4f527cf72cefcab652819baeba2c0f.pdf
2013-07-01
169
176
10.22038/ijorl.2013.661
Cognition
Dichotic Auditory Memory Test
Hearing Loss
Memory disorders
Presbycusis
Zahra
Shahidipour
z_shahidipour@yahoo.com
1
Department of Audiology, Faculty of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Ahmad
Geshani
amdke2000@yahoo.com
2
Department of Audiology, Faculty of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Zahra
Jafari
zahra.acn@gmail.com
3
Rehabilitation Research Center, Faculty of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Shohreh
Jalaie
4
Department of Statistic, Faculty of Management, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Elham
Khosravifard
5
4Department of Audiology, Faculty of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran Iran.
AUTHOR
ORIGINAL_ARTICLE
Submental Artery Island Flap in Reconstruction of Harde Plate after wide Surgical Resection of Veruccous Carcinoma.
Two case reports
Introduction: Reconstruction of intraoral soft tissue defects is important in restoring function and esthetic. In large defects, there will be demand for regional pedicle flaps or free flaps. Hard palate separates nasal and oral cavities. Due to the small surface area between flap and remaining palate after surgical resections, optimal blood supply of the flaps for hard palate reconstructions are needed. This article demonstrates immediate reconstruction of two edentulous hemimaxillectomy patients with submental artery Island flap and brief review of this flap discussed.
https://ijorl.mums.ac.ir/article_664_1ced9403822f09c60eea74a14dcd1970.pdf
2013-07-01
177
181
10.22038/ijorl.2013.664
Facial artery
Hemimaxillectomy
Surgical flaps
Amin
Rahpeyma
rahpeymaa@mums.ac.ir
1
Oral and Maxillofacial Diseases Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Saeedeh
Khajehahmadi
2
2Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Mohammadreza
Nakhaei
3
2Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
ORIGINAL_ARTICLE
Ectopic Supernumerary Tooth in Nasal Septum:
A Case Study
Introduction: Nasal teeth eruption is a rare phenomenon. The variability of symptoms and generic history makes the diagnosis difficult. This difficulty is more challenging when the tooth is placed in the depth of septum. Case Report: Our case is an example of this problem. Herein, we present a case of intraseptal tooth with nasal obstruction and septal deviation and recurrent sinusitis. We present preoperative imaging. Conclusion: Great suspicion may helpful for preoperative diagnosis and good deciding.
https://ijorl.mums.ac.ir/article_665_32328baead90e1de73f77fc04894a309.pdf
2013-07-01
183
186
10.22038/ijorl.2013.665
Ectopic teeth
Septal deviation
Supernumerary
tooth
Saleh
Mohebbi
mohebbi54@gmail.com
1
Department of Otorhinolaryngology.Tehran University of Medical Sciences,Tehran,Iran.
AUTHOR
Oveis
Salehi
2
Department of Otorhinolaryngology.Hormozgan University of Medical Sciences,Bandarabbas,Iran.
AUTHOR
Sedighe
Ebrahimpoor
3
3Cell and molecular biology,biochemistMsc,Research center of otolaryngology –head and neck surgery,Iran university of medical sciences,Tehran,Iran.
AUTHOR
ORIGINAL_ARTICLE
Ectopic Molar with Maxillary Sinus Drainage Obstruction
and Oroantral Fistula
Introduction: Ectopic tooth eruption may result owing to one of 3 processes: developmentalDisturbance, iatrogenic activity, or pathologic process, such as a tumor or a cyst. In rare cases, occlusion of the sinus ostia may predispose a patient to develop a maxillary sinus mucocele. When the maxillary sinus is invaded, symptoms usually occur late in the process. Case report: A 17 years old boy referred to department of Otolaryngology, Head and Neck Surgery of university of medical sciences, Tabriz_Iran in 2010 with chronic recurrent mucoprulent discharge from retromollar trigone , posterior to right superior alveolar ridge. CT scan revealed a dense mass resembling tooth, obstructing sinus ostium with homogenous opacity with ring enhancement, occupying whole sinus and expanding all walls. A Caldwell Luke approach in combination with endoscopy was selected. Discussions: In the present patient, removal of ectopic tooth resolved the symptoms completely, the fistula obstructed and discharges discontinued. An ectopic tooth is a rare entity obstructing sinus ostium. The etiology of ectopic eruption has not yet been completely clarified, but many theories have been suggested,including trauma, infection, developmental anomalies and pathologic conditions, such as dentigerous cysts. In summary, although the ectopic teeth is rare but it would be assumed in presence of unilateral symptoms of sinonasal cavity. Therefore in peristant unilateral sinonasal symptoms we should complete examining of this site to rule out rare causes of these symptoms.
https://ijorl.mums.ac.ir/article_666_46dd3439333a3317b1511f5c71230f21.pdf
2013-07-01
187
192
10.22038/ijorl.2013.666
Ectopic molar
Maxillary sinus ostia
Oroantral fistulae
Shahin
Abdollahifakhim
1
Departments of Otorhinolaryngolog, Tabriz University of Medical Sciences, Tabriz, Iran.
AUTHOR
Mehrnoush
Mousaviagdas
2
Departments of Otorhinolaryngolog, Tabriz University of Medical Sciences, Tabriz, Iran.
AUTHOR