ORIGINAL_ARTICLE
CenoDerm vs. Fascia lata for the Prevention of Dorsal Nasal Irregularities in Rhinoplasty
Introduction: Dorsal nasal irregularity is a complication of rhinoplasty surgery, mostly seen in patients with thin skin. Acellular dermis (CenoDerm) and homologous fascia lata covering the nasal bone cartilage structure have been used to achieve a smooth surface. In this study, we aimed to investigate clinical outcomes using these two materials. Materials and Methods: After a standard rhinoplasty procedure, a layer of the acellular dermis or homologous fascia lata was placed in the pocket of the dorsum. Patients were evaluated for clinical outcomes at 3, 6, and 12 months after the procedure. Results: Forty-two of 68 patients completed the follow-up period. Patient satisfaction was higher in the homologous fascia lata group. Similarly, nasal dorsum inspection and palpation results were better in the homologous fascia lata group compared with the CenoDerm group but was significant in palpation (P=0.00). There was no complete absorption in the homologous fascia lata group 6 months after surgery (P= 0.04 vs. CenoDerm) but no significant difference was observed at 12 months. Conclusion: Homologous fascia lata is better than acellular dermis in preventing dorsal nasal irregularity after rhinoplasty in thin-skinned patients.
https://ijorl.mums.ac.ir/article_7033_4f5e1150039efea54516ee23e14b96df.pdf
2016-07-01
241
248
10.22038/ijorl.2016.7033
Acellular dermis
Fascia lata
Rhinoplasty
Alireza
Mohebbi
mohebbidr@gmail.com
1
Otolaryngology Research Center, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
AUTHOR
Roghayeh
Hamidian
hamidian.r@gmail.com
2
Department of Otolaryngology, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
LEAD_AUTHOR
Seyed Behzad
Poosti
sb_pousti@yahoo.com
3
Otolaryngology Research Center, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
AUTHOR
Seyedeh Simindokht
Hosseini
simindokht_hosseini@yahoo.com
4
Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
1. Cologlu H, Uysal A, Tiftikcioglu YO, Oruc M, Kocer U, Coskun E, et al. Comparison of Autogenous Cartilage, Acellular dermis, and Solvent-Dehydrated Pericardium for the Prevention and Correction of Dorsal Nasal Irregularities: An Experimental Study. Aesth Plast Surg. 2012; 36(3):732–41.
1
2. Lin G, Lawson W. Complications using grafts and implants in rhinoplasty. Operative Techniques in Otolaryngology 2007; 18(4):315–23.
2
3. Sang Yu M, Sung Park H, Jin Lee H, Ju Jang Y. Histomorphological Changes of Tutoplast-Processed Fascia Lata Grafts in a Rabbit Rhinoplasty Model. Otolaryngology Head and Neck Surgery 2012; 147(2): 239–44.
3
4. Gryskiewicz JM. Dorsal Augmentation with AlloDerm. Semin Plast Surg 2008; 22(2):90–103.
4
5. Kissane NA, Itani KM. A decade of ventral incisional hernia repairs with biologic acellular dermal matrix: what have we learned? Plast and Reconstr Surg 2012; 130 (5s-2): 194–202.
5
6. Janis JE, O’Neill AC. Acellular dermal matrices in abdominal wall reconstruction: a systematic review of the current evidence. Plast Reconstr Surg 2012; 130(5s-2): 183-93.
6
7. Sheridan RL, Choucair RJ. Acellular allogenic dermis does not hinder initial engraftment in burn wound resurfacing and reconstruction. J Burn Care Rehabil 1977; 18(6):496–9.
7
8. Fisher E, Frodel JL. Facial suspension with acellular human dermal allograft. Arch Facial Plast Surg 1999; 1(3):195–9.
8
9. Tobin HA, Karas ND. Lip augmentation using an alloderm graft. J Oral Maxillofac Surg 1998; 56: 722–7.
9
10. Jackson IT, Yavuzer R. AlloDerm for dorsal nasal irregularities. Plast Reconstr Surg 2001;107(2):553–8.
10
11. Ghoniem GM. Allograft sling material: is it state of the art? Int Uro-gynecol J Pelvic Floor Dysfunct 2000; 11(2):69–70.
11
12. Sclafani AP, McCormick SA, Cocker R. Biophysical and microscopic analysis of homologous dermal and fascial materials for facial aesthetic and reconstructive uses. Arch Facial Plast Surg 2002; 4:164-71.
12
13. Gryskiewicz JM. Waste not, want not: The use of AlloDerm in secondary rhinoplasty. Plast Reconstr Surg 2005;116(7):1999–2004.
13
14. Ju Jang Y, Hwan Wang J, Sinha V, Song HM, Lee BJ. Tutoplast-processed Fascia Lata for dorsal augmentation in rhinoplasty. Otolaryngology–Head and Neck Surgery 2007; 137(1):88–92.
14
15. Tarhan E, Cakmak O, Ozdemir BH, Akdogan V, Suren D. Comparison of AlloDerm, fat, fascia, cartilage, and dermal grafts in rabbits. Arch Facial Plast Surg 2008;10(3):187–193.
15
16. Sajjadian A, Naghshineh N, Rubinstein R. Status of Grafts and Implants in Rhinoplasty: Part II. Homologous Grafts and Allogenic Implants. Plastic and Reconstructive Surgery 2010;125(3):99–109.
16
17. Lee DW, Lee MC, Roh H, Lee WJ. Multilayered implantation using acellular dermal matrix into nude mice. J Materials Science. Materials in Medicine 2014; 25(12):2669-76.
17
ORIGINAL_ARTICLE
Effects of Steroids and Curcumin on Prevention of Laryngeal Stenosis Secondary to Trauma
Introduction: The aim of this study was to compare the preventive effects of corticosteroids and curcumin on subglottic stenosis in an animal model. Materials and Methods: Twenty-one male German Shepherd dogs were used for this study. After standardized trauma to the subglottic area, the dogs were divided into three groups. Group A received curcumin (450 mg/ day) for 15 days; Group B received beclomethasone (2 puffs/day, 50 µg/dose) for 15 days; Group C received saline spray only. At 6 weeks after the injury, the larynx specimens were examined histopathologically to assess epithelialization, inflammation, and fibrosis. Results: Complete epithelial covering of the steroid-treated group was significantly less than that of the control group. Despite inflammation and fibrosis, there was no significant difference between the steroid and control groups. In the curcumin-treated group, there was no significant difference between the groups. Conclusion: Topically applied steroid decreases epithelialization after induced subglottic injury. It is recommended that further studies be conducted in order to investigate the effects of the two drugs on airway stenosis prevention.
https://ijorl.mums.ac.ir/article_7040_25e1f75834fb2b8eb91c6ccf5e7ab093.pdf
2016-07-01
249
254
10.22038/ijorl.2016.7040
Corticosteroids
Curcumin
Laryngeal stenosis
Laryngeal scar
Kamyar
Iravani
iravanika@sums.ac.ir
1
Department of Otorhinolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran.
LEAD_AUTHOR
Zahra
Babaie
mahtab_169@yahoo.com
2
Department of Otorhinolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran.
AUTHOR
Mohammad Javad
Ashraf
ashrafm@sums.ac.ir
3
Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran.
AUTHOR
Nader
Tanided
tanifehn@gmail.com
4
Stem cell and Transgenic Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
AUTHOR
1. Ertugrul EE, Cekin IE, Cincik H, Dogra S, Gungor A. Effectiveness of topically applied halofuginone in management of subglottic stenosis in rats.Otolaryngol Head Neck Surg 2009; 140:720–3.
1
2. Talas DU, Nayci A, Atis S, Comelekoglu U, Polat A, Bagdatoglu C, et al. The effects of corticosteroids and vitamin A on the healing of tracheal anastomoses. Int J Pediatr Otorhinolaryngol 2003;67:265–71.
2
3. Cincik H, Gungor A, Cakmak A, Omeroglu A, Poyrazoglu E, Yildirim S, et al. The effects of mitomycin C and 5- fluorouracil / triamcinolone on fibrosis/ scar tissue formation secondary to subglottic trauma (experimental study). Am J Otolaryngol 2005; 26: 45–50.
3
4. Krishna P, Rosen CA, Branski RC, Wells A, Hebda PA. Primed fibroblasts and exogenous decorin: potential treatments for subacute vocal fold scar. Otolaryngol Head Neck Surg 2006; 135(6):937–45.
4
5. Barnes PJ. Molecular mechanisms and cellular effects of glucocorticosteroids. Immunol Allergy Clin North Am 2005;25: 451–68.
5
6. Cato Ac, Wade E. Molecular mechanisms of anti-inflammatory action of glucocorticoids. Bioessays 1996;18: 371–8.
6
7.Chrousos G. Adenocorticosteroids and adenocortical antagonist. In: Katzung B, Masters S, Trevor A. Basic and Clinical Pharmacology.12th edition, United States: McGraw-Hill; 2012:697–713.
7
8.Skigen AL, Bedrock RD, Stopperich PS. Correction of the depressed, retracted, post-tracheostomy scar. Plast Reconstr Surg 1999;103: 1703-5.
8
9. Kim CS, Buchmiller TL, Fonkalsrud EW, Phillips JD. The effects of anabolic steroids on ameliorating the adverse effects of chronic corticosteroids on intestinal anastomotic healing in rabbits. Surg Gynecol Obstet 1993; 176: 73–9.
9
10. Healy GB. An experimental model for the endoscopic correction of subglottic stenosis with clinical applications. Laryngoscope 1982;92:1103-15.
10
11. Talas DU, Nayci A, Atis S, Polat A, Comelekoglu U, Bagdatoglu C, et al. The effects of corticosteroids on the healing of tracheal anastomoses in a rat model. Pharmacol Res 2002; 45:299–304.
11
12. Wicke C, Halliday B, Allen D, Roche NS, Scheuenstuhl H, Spencer MM, et al. Effects of steroids and retinoids on wound healing. Arch Surg 2000; 135:1265–70.
12
13. Anand P, Kunnumakkara AB, Newman RA, Aggarwal BB. Bioavailability of curcumin: problems and promises. Mol Pharm 2007; 4: 807–18.
13
14. Aggarwal BB, Kumar A, Bharti AC. Anticancer Potential of curcumin: preclinical and clinical studies. Anticancer Res 2003; 23(1A): 363– 98.
14
15. Epstein J, Sanderson IR, Macdonald TT. Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies. Br J Nutr 2010; 103: 1545–57.
15
16. Singh S, Aggarwal BB. Activation of transcription factor NF-Kappa B is suppressed by curumin (diferuloylmethane). J Biol Chem 1995; 270: 24995–5000.
16
17. Anest V, Hanson JL, Cogswell PC, Steinbrecher KA, Strahl BD, Baldwin AS. A nucleosomal function for Ikappa B Kinase-alpha in NF-kappa B-dependent gene expression. Nature 2003; 423:659–63.
17
18. Shishodia S, Potdar P, Gairola CG, Aggarwal BB. Curcumin (diferuloyl methane) down-regulates cigarette smoke-induced NF-kappa B activation through inhibition of l-kappa alpha kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1. Carcinogenesis 2003; 24:1269–79.
18
19. Rafiee P, Nelson VM, Manley S, Wellner M, Floer M, Binion DG, et al. Effect of curcumin on acidic PH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET 1A): role of PKC, MAPKs and NF-Kappa B. Am J Physiol Gastrointest Liver Physiol 2009; 296: G388–98.
19
20. Ingrams DR, Sukin SW, Ashton P, Valtonen HJ, Pankratov MM, Shapshay SM. Does slow–release 5-fluorouracil and triamcinolone reduce subglottic stenosis? Otolaryngol Head Neck Surg1998; 118:174–7.
20
21. Yoon YH, Rha KS, Koo BS, Park JY, Kim YM, Park YH. The preventive effect of halofuginone on posterior glottic stenosis in a rabbit model. Otolaryngol Head Neck Surg 2008; 139:94–9.
21
22. Roh JL. Prevention of posterior glottic stenosis by mitomycin C. Ann Otol Rhinol Laryngol 2005; 114:558;62.
22
ORIGINAL_ARTICLE
Facial Nerve Monitoring During Parotidectomy: A Two-Center Retrospective Study
Introduction: We present a retrospective two-center study series and discussion of the current literature to assess the benefits of facial nerve monitoring during parotidectomy. Materials and Methods: From 2007 to 2012, 128 parotidectomies were performed in 125 patients. Of these, 47 procedures were performed without facial nerve monitoring (group 1) and 81 with facial nerve monitoring (group 2). The primary endpoint was the House-Brackmann classification at 1 month and 6 months. Facial palsy was determined when the House-Brackmann grade was 3 or higher. Results: In group 1, 15 facial palsies were noted; 8 were transient and 7 were definitive. In group 2, 19 facial palsies were noted; 12 were transient and 7 were definitive. At both one and six months after parotidectomy, the rate of facial palsy in reoperation cases was significantly higher in group 1 than in group 2. Conclusion: Facial nerve monitoring is a simple, effective adjunct method that is available to surgeons to assist with the functional preservation of the facial nerve during parotid surgery. Although it does not improve the facial prognosis in first-line surgery, it does improve the facial prognosis in reoperations.
https://ijorl.mums.ac.ir/article_7034_ed5a3e11119c0cc1084d59688836dae7.pdf
2016-07-01
255
260
10.22038/ijorl.2016.7034
Facial Nerve
Facial paralysis
Intraoperative Monitoring
Parotid gland
Reoperation
Stanislas
Ballivet de Régloix
stanbdr@msn.com
1
Department of Otorhinolaryngology – Head and Neck Surgery, Military Training Hospital Percy 101, avenue Henri Barbusse 92140 Clamart, France.
LEAD_AUTHOR
Julia
Grinholtz Haddad
jg@hotmail.fr
2
Department of Otorhinolaryngology – Head and Neck Surgery, Versailles Hospital Center, André Mignot Hospital 177, rue de Versailles 77157 Le Chesnay cedex, France.
AUTHOR
Olga
Maurin
om@hotmail.fr
3
Department of Otorhinolaryngology – Head and Neck Surgery, Military Training Hospital Percy 101, avenue Henri Barbusse 92140 Clamart, France.
AUTHOR
Louise
Genestier
lh@hotmail.fr
4
Department of Otorhinolaryngology – Head and Neck Surgery, Military Training Hospital Val de Grâce74, boulevard de Port Royal 75005 Paris, France.
AUTHOR
Quentin
Lisan
ql@hotmail.fr
5
Department of Otorhinolaryngology – Head and Neck Surgery, Military Training Hospital Percy 101, avenue Henri Barbusse 92140 Clamart, France.
AUTHOR
Yoann
Pons
yp@gmail.fr
6
Department of Otorhinolaryngology – Head and Neck Surgery, Military Training Hospital Percy 101, avenue Henri Barbusse 92140 Clamart, France.
AUTHOR
1. Dulguerov P, Marchal F, Lehmann W. Postparotidectomy facial nerve paralysis: possible etiologic factors and results with routine facial nerve monitoring. Laryngoscope 1999. 109(5): 754-62.
1
2. Eisele DW, Wang SJ, Orloff LA. Electrophysiologic facial nerve monitoring during parotidectomy. Head Neck 2010. 32(3): 399-405.
2
3. Witt RL. Facial nerve monitoring in parotid surgery: the standard of care ? Otolaryngol Head Neck Surg 1998.119(5): 468-70.
3
4. Terrell JE, Kileny PR, Yian C, Esclamado RM, Bradford CR, Pillsbury MS, et al. Clinical outcome of continuous facial nerve monitoring during primary parotidectomy. Arch Otolaryngol Head Neck Surg 1997. 123(10): 1081-7.
4
5. Anon JB, Lipman SP, Guelcher RT, Sibly DA, Thumfart W. Monitoring the facial nerve during parotidectomy. Arch Otolaryngol Head Neck Surg 1991. 117(12): 1420.
5
6. Bensadoun R-J, Dassonville O, Rousmans S. Recommendations for management of patients with salivary gland malignant tumours (excluding lymphoma, sarcoma and melanoma), summary report. Bull Cancer (Paris). 2008. 95(7-8): 735-49.
6
7. Deneuve S, Quesnel S, Depondt J, Albert S, Panajotopoulos A, Gehanno P, et al. Management of parotid gland surgery in a university teaching hospital. Eur Arch Oto-Rhino-Laryngol 2010. 267(4): 601-5.
7
8. Brennan J, Moore EJ, Shuler KJ. Prospective analysis of the efficacy of continuous intraoperative nerve monitoring during thyroidectomy, parathyroidectomy, and parotidectomy. Otolaryngol Head Neck Surg 2001. 124(5): 537-43.
8
9. Grosheva M, Klussmann JP, Grimminger C,
9
Wittekindt C, Beutner D, Pantel M, et al. Electromyographic facial nerve monitoring during parotidectomy for benign lesions does not improve the outcome of postoperative facial nerve function: a prospective two-center trial. Laryngoscope 2009. 119(12): 2299-305.
10
10. Lee D-H. In reference to Electromyographic facial nerve monitoring during parotidectomy for benign lesions does not improve the outcome of postoperative facial nerve function: a prospective two-center trial. Laryngoscope 2010. 120(4): 863; author reply 864.
11
11. Pons Y, Clément P, Crambert A, Conessa C. Facial nerve monitoring in the parotidectomy. Rev Laryngol Otol Rhinol (Bord) 2010. 131(4-5):253-6.
12
12. Reilly J, Myssiorek D. Facial nerve stimulation and postparotidectomy facial paresis. Otolaryngol Head Neck Surg 2003. 128(4):530-3.
13
13. López M, Quer M, León X, Orús C, Recher K, Vergés J. Usefulness of facial nerve monitoring during parotidectomy. Acta Otorrinolaringol Esp 2001. 52(5):418-21.
14
14. Meier JD, Wenig BL, Manders EC, Nenonene EK. Continuous intraoperative facial nerve monitoring in predicting postoperative injury during parotidectomy. Laryngoscope 2006. 116(9):1569-72.
15
15. Makeieff M, Venail F, Cartier C, Garrel R, Crampette L, Guerrier B. Continuous facial nerve monitoring during pleomorphic adenoma recurrence surgery. Laryngoscope 2005. 115(7):1310-4.
16
16. Fakhry N, Hervé JF, Michel J, Santini L, Piller P, Giovanni A. Giant pleomorphic adenoma of the deep lobe of the parotid gland: role of MRI and nerve monitoring in facial nerve localization. Rev Laryngol Otol Rhinol (Bord) 2011. 132(4-5):233-5.
17
17. Guntinas-Lichius O, Klussmann JP, Wittekindt C, Stennert E. Parotidectomy for Benign Parotid Disease at a University Teaching Hospital: Outcome of 963 Operations. Laryngoscope 2006. 116(4):534-40.
18
18. Mamelle E, Bernat I, Pichon S, Granger B, Sain-Oulhen C, Lamas G, et al. Supramaximal stimulation during intraoperative facial nerve monitoring as a simple parameter to predict early functional outcome after parotidectomy. Acta Otolaryngol 2013. 133(7): 779-84.
19
19. Witt RL. Facial nerve monitoring in parotid surgery: the standard of care? Otolaryngol Head Neck Surg 1998. 119(5):468-70.
20
20. Haenggeli A, Richter M, Lehmann W, Dulguerov P. A complication of intraoperative facial nerve monitoring: facial skin burns. Am J Otol 1999. 20(5): 679-82.
21
ORIGINAL_ARTICLE
HLA-Cw Allele Frequency in Definite Meniere’s Disease Compared to Probable Meniere’s Disease and Healthy Controls in an Iranian Sample
Introduction Several lines of evidence support the contribution of autoimmune mechanisms in the pathogenesis of Meniere’s disease. The aim of this study was determining the association between HLA-Cw Alleles in patients with definite Meniere’s disease and patients with probable Meniere’s disease and a control group. Materials and Methods: HLA-Cw genotyping was performed in 23 patients with definite Meniere’s disease, 24 with probable Meniere’s disease, and 91 healthy normal subjects, using sequence specific primers polymerase chain reaction technique. The statistical analysis was performed using stata 8 software. Results: There was a significant association between HLA-Cw*04 and HLA-Cw*16 in both definite and probable Meniere’s disease compared to normal healthy controls. We observed a significant difference in HLA-Cw*12 frequencies between patients with definite Meniere’s disease compared to patients with probable Meniere’s disease (P=0.04). The frequency of HLA-Cw*18 is significantly higher in healthy controls (P=0.002). Conclusion: Our findings support the rule of HLA-Cw Alleles in both definite and probable Meniere’s disease. In addition, differences in HLA-Cw*12 frequency in definite and probable Meniere’s disease in our study’s population might indicate distinct immune and inflammatory mechanisms involved in each condition.
https://ijorl.mums.ac.ir/article_7049_c6a914fc1276b690a662cdc71114792f.pdf
2016-07-01
261
266
10.22038/ijorl.2016.7049
HLA-Cw
Immunogenetics
Meniere’s disease
Sasan
Dabiri
sasan.dabiri@gmail.com
1
Otorhinolaryngology Research Center, AmirAlam Hospital, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
Fatemeh
Ghadimi
fatemeh.ghadimi@gmail.com
2
Otorhinolaryngology Research Center, AmirAlam Hospital, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
mohammadreza
Firouzifar
link2mrfs@gmail.com
3
Otorhinolaryngology Research Center, AmirAlam Hospital, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
Nasrin
Yazdani
n_yazdani@tums.ac.ir
4
Otorhinolaryngology Research Center, AmirAlam Hospital, Tehran University of Medical Sciences, Tehran, Iran
LEAD_AUTHOR
Mahsa
Mohammad Amoli
amolimm@tums.ac.ir
5
Endocrinology and Metabolism Research Center, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Varasteh
Vakili
vari_01@yahoo.com
6
Otorhinolaryngology Research Center, AmirAlam Hospital, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
Zahra
Mahvi
z.mahvi69@gmail.com
7
Otorhinolaryngology Research Center, AmirAlam Hospital, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
1. Wright T. Meniere’s disease. BMJ Clin Evid. 2015(9636):406–14.
1
2. Arweiler DJ, Jahnke K, Grosse-Wilde H. Meniere disease as an autosome dominant hereditary disease. Laryngorhinootologie 1995;74(8):512–5.
2
3. Fung K, Xie Y, Hall SF, Lillicrap DP, Taylor SA. Genetic basis of familial Meniere’s disease. J Otolaryngol 2002;31(1):1–4.
3
4. Greco A, Gallo A, Fusconi M, Marinelli C, Macri GF, de Vincentiis M. Meniere’s disease might be an autoimmune condition? Autoimmun Rev 2012; 11(10): 731–8.
4
5. Klein JAN, Sato A. The HLA system. First of two parts. N Engl J Med 2000;343(10):702–9.
5
6. Klein J, Sato A. Adv Immunol hla Syst Second two parts.The New Engl J Med 2000;343 SRC -:782–6.
6
7. Svejgaard A. HLA and autoimmune diseases. Allergy 34(5):275–81.
7
8. Jawahar G, Natarajan M. Chronic extradural haematoma. J Indian Med Assoc. 83(12):413,416.
8
9. McCabe BF. Autoimmune sensorineural hearing loss. Ann Otol Rhinol Laryngol 1979;88(5):585-9.
9
10. Brookes GB. Circulating immune complexes in Meniere’s disease. Arch Otolaryngol Head Neck Surg 1986;112(5):536–40.
10
11. Hughes GB, Kinney SE, Barna BP, Calabrese LH. Autoimmune reactivity in Meniere’s disease: A preliminary report. Laryngoscope 1983;93(4):410–7.
11
12. Gottschlich S, Billings PB, Keithley EM, Weisman MH, Harris JP. Assessment of serum antibodies in patients with rapidly progressive sensorineural hearing loss and Meniere’s disease. Laryngoscope. Division of Head and Neck Surgery 1995;105(12 Pt 1): 1347–52.
12
13. Khorsandi M-T, Amoli MM, Borghei H, Emami H, Amiri P, Amirzargar A. Associations between HLA-C alleles and definite Meniere’s disease. Iran J Allergy Asthma Immunol 2011; 10(2): 119–22.
13
14. Monsell EM. New and revised reporting guidelines from the Committee on Hearing and Equilibrium. Otolaryngology-Head and Neck Surgery 1995;113(3):176–8.
14
15. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16(3):1215.
15
16. Koyama S, Mitsuishi Y, Bibee K, Watanabe I, Terasaki PI. HLA associations with Menière’s disease. Acta Otolaryngol 1993;113(5):575–8.
16
17. Xenellis J, Morrison AW, McClowskey D, Festenstein H. HLA antigens in the pathogenesis of Menière’s disease. J Laryngol Otol 1986;100(1):21-4.
17
18. Melchiorri L, Martini A, Rizzo R, Berto A, Adinolfi E, Baricord OR. Human leukocyte antigen-A, -B, -C and -DR alleles and soluble human leukocyte antigen class I serum level in Ménière’s disease. Acta Otolaryngol Suppl 2002;(548):26–9.
18
19. Yeo SW, Park S-N, Jeon E-J, Lee H-Y, Pyo C-W, Kim T-G. Influence of human leukocyte antigen in the pathogenesis of Meniere’s disease in the South Korean population. Acta Otolaryngol 2002;122(8): 851–6.
19
20. Lopez-Escamez JA, Vilchez JR, Soto-Varela A, Santos-Perez S, Perez-Garrigues H, Aran I, et al. HLA-DRB1*1101 allele may be associated with bilateral Meniere’s disease in southern European population. Otol Neurotol ; 2007;28(7):891–5.
20
ORIGINAL_ARTICLE
Analysis of Epstein Barr Virus Encoded RNA Expression in Nasopharyngeal Carcinoma in North-Eastern India: A Chromogenic in Situ Hybridization Based Study
Introduction: Nasopharyngeal carcinoma (NPC) is a common cancer in the North-East region of India. Though the role of environmental contributors of NPC in the North-Eastern part of India is firmly established, EBV as an etiological agent in the region remains unexplored. Material and Methods: Fifty-one patients, who presented at the department of ENT, NEIGRIHMS and were confirmed as NPC upon histopathological examination, were included in the study. Chromogenic in-situ hybridization (CISH) was used for the evaluation of EBER (Epstein Barr Virus Encoded RNA). Presence of nuclear signals was taken as positive for EBER expression. EBER status was correlated with various clinicopathological parameters like age, sex, dietary habits, histological types of NPC, and ethnicity of the patients. Results: The age range of the study group was 25 to 70 years with a mean age of 44.64 years and a male:female ratio of 3:2. Non-keratinizing undifferentiated type of NPC was the most common histological type. EBV was positive in 59% (30/51) of our cases. It showed a statistically significant correlation with the Naga community (P=0.01), with consumption of smoked food (P=0.02), and cigarette smoking (P=0.02). There was no correlation of EBV with age, sex, lymph node metastasis, stage, and histology. Conclusion: Our result indicates that EBV may be an additional risk factor in the pathogenesis of NPC in this region of India. So apart from lifestyle modification, a future study for a screening test for EBV viral load even in asymptomatic patients may be considered, for determination of disease susceptibility, early diagnosis, and proper management.
https://ijorl.mums.ac.ir/article_7036_db6e8feb02ddabcbde086f57b0df239c.pdf
2016-07-01
267
274
10.22038/ijorl.2016.7036
EBV
EBER
Nasopharynx
nasopharyngeal cancer
CISH
Anjan
Saikia
anjanamch14@gmail.com
1
Department of Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
AUTHOR
Vandana
Raphael
raphaellyngdoh@gmail.com
2
Department of Pathology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, India.
LEAD_AUTHOR
N. Brian
Shunyu
drnbshunyu@yahoo.com
3
Department of Otorhinolaryngology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, India.
AUTHOR
Yookarin
Khonglah
yookarink@gmail.com
4
Department of Pathology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, India.
AUTHOR
Jaya
Mishra
jayamishraxyz@gmail.com
5
Department of Pathology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, India.
AUTHOR
Ankit
Jitani
ankitjitani@gmail.com
6
Department of Pathology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, India.
AUTHOR
Jayanta
Medhi
jm_17f@rediffmail.com
7
Department of Otorhinolaryngology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, India.
AUTHOR
1. Sharma TD, Singh TT, Laishram RS, Sharma LDC, Sunita AK, Imchen LT. Nasopharyngeal Carcinoma- A Clinico-pathological Study in a Regional Cancer Centre of North-eastern India. Asian Pacific J Cancer. 2011; 12: 1583-7.
1
2. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011; 61: 69-90.
2
3. Ferley J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, method and major patterns in GLOBOCAN 2012. Int J Cancer. 2015; 136(5): 359-86.
3
4. Kumar S , Zinyu R , Singh IKK , Medhi SB, Baruah T, Das B, et al. Studies on Nasopharyngeal cancer with reference to the North-Eastern region of India. Ann Natl Acad Med Sci. 1996; 32:199.
4
5. Wei KR, Xu Y, Liu J, Zhang WJ, Liang ZH. Histopathological Classification of Nasopharyngeal Carcinoma. Asian Pacific J Cancer. 2011; 12: 1141-47.
5
6. Krishna SM , James S, Sreelekha TT, Kattoor J, Balaram P. Primary Nasopharyngeal Cancer of Indian Origin and the Viral Link - A Preliminary Study. Asian J of Cancer. 2006; 5: 241-52.
6
7. Liu MT, Hsieh CY, Chang TH, Lin JP, Huang CC, Wang AY. Prognostic factor affecting the outcome of nasopharyngeal carcinoma. Jpn J clin oncol. 2003; 33(10): 501-8.
7
8. Jitani AK , Raphael V , Mishra J , Shunyu NB, Khonglah Y, Medhi J . Analysis of Human Papilloma Virus 16/18 DNA and its correlation with p16 expression in oral cavity squamous cell carcinoma in North Eastern India : A chromogenic in situ hybridization based study. J Clin Diagn Res. 2015; 9(8): EC04-7.
8
9. Chang ET, Adami HO. The Enigmatic Epidemiology of Nasopharyngeal Carcinoma. Cancer Epidemiol Biomarkers. 2006; 15: 1765-77.
9
10. Macmohan B. Epidemiology and Hodgkin disease. Cancer Res. 1966; 26: 1189-201.
10
11. Brooks L, Yao QY, Rickinson AB, Young LS. Epstein Barr Virus latent gene transcription in nasopharyngeal carcinoma cells: co-expression of EBNA1, LMP1 and LMP2 transcripts. J Virol. 1992; 66(5): 2689-97.
11
12. Pathmanathan R, Prasad U, Chandrika G, Sadler R, Flynn K, Raab-Traub N. Undifferentiated, nonkeratinizing, and squamous cell carcinoma of the nasopharynx. Am J Pathol. 1995; 146(6): 1355-67.
12
13. Cheng YJ, Hildesheim A, Hsu MM, Chen IH, A. Brinton L, H. Levine O, et al. Cigarette smoking, alcohol consumption and risk of nasopharyngeal carcinoma in Taiwan. Cancer Causes Control. 1999; 10(3): 201-7.
13
14. Chen L, Gallicchio L, Boyd-Lindsley K, Tao XG, Robinson KA, Lam TK, et al. Alcohol consumption and the risk of Nasopharyngeal carcinoma: A systemic review. Nutr Cancer. 2008; 61: 1-15.
14
15. Kataki AC, Simons MJ, Das AK, Sharma K, Mehra NK. Nasopharyngeal carcinoma in the North-eastern states of India. Chin J Cancer. 2011; 30(2): 106-13.
15
16. Tsai ST, Jin YT, Mann RB, Ambinder RF. Epstein-barr virus detection in nasopharyngeal tissues of patients with suspected nasopharyngeal carcinoma. Cancer. 1998; 82(8): 1449-53.
16
17. Wu TC, Mann RB, Epstein IJ, MacMahon E, Lee WA, Charache P, et al. Abundant Expression of EBER1 Small Nuclear RNA in Nasopharyngeal Carcinoma: A Morphologically Distinctive Target for Detection of Epstein-Barr Virus in Formalin-fixed Paraffin-embedded Carcinoma Specimens. Am J Pathol. 1991; 138(6): 1461-69.
17
18. Hanel P, Hummel M, Anagnostopoulos I, Stein H. Analysis of single EBER-positive and negative tumour cells in EBV-harbouring B-cell non-Hodgkin lymphomas. J Pathol. 2001; 195(3): 355-60.
18
19. Broussset P, Butet V, Chittal S, Selves J, Delsol G. Comparison of in-situ hybridization using different non isotopic probes for detection of EBV in nasopharyngeal carcinoma and IHC correlation with anti-latent membrane protein antibody. Lab Invest. 1992; 67(4): 457-64.
19
20. Murono S, Yoshizaki T, Tanaka S, Takeshita H, Park C, Furukawa M. Detection of Epstein-Barr virus in nasopharyngeal carcinoma by in situ hybridization and polymerase chain reaction. Laryngoscope. 1997; 107(4): 523-26.
20
21. Mäkitie AA, MacMillan C, Ho J, Shi W, Lee A, O’Sullivan B, et al. Loss of p16 expression has prognostic significance in human nasopharyngeal carcinoma. Clin Cancer Res. 2003; 9: 2177-84.
21
ORIGINAL_ARTICLE
Asthma in Rhinosinusitis: A Survey from Iran
Introduction: The coexistence of asthma and chronic rhinosinusitis (CRS) is more common than expected given their individual prevalence in the general population and may affect patient’s quality of life. The aim of this study was to evaluate the prevalence of asthma in chronic rhinosinusitis in Mashhad, Northeast Iran. Materials and Methods: This study was performed in two university hospital from November 2012 for 12 months. In total, 153 patients with chronic rhinosinusitis were enrolled and referred to a particular pulmonologist for asthma evaluation. Results: The mean age of participants was 40.54±13.11 years, and 41.8% were male. In total, 63.4% of patients had the polypoid form of CRS. The proportion of patients in this study with asthma was 41.8%, compared with a general asthma prevalence in this region of 13.5%. Conclusion: There is a high prevalence of asthma among patients with CRS, but it often remains undiagnosed. Asthma in CRS patients should be diagnosed and treated in order to improve patient’s quality of life. We recommend an evaluation of the lower airways in all of these patients as well as further studies in this field.
https://ijorl.mums.ac.ir/article_7046_20f9074bd7697588433f34bebed51aed.pdf
2016-07-01
275
280
10.22038/ijorl.2016.7046
Asthma
Sinusitis
Spirometry
Mehdi
Bakhshaee
bakhshaeem@mums.ac.ir
1
Sinus and Surgical Endoscopic Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Mohamad Reza
Majidi
majidimr@mums.ac.ir
2
Sinus and Surgical Endoscopic Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Vahideh
Gharavi
v_gharavi@yahoo.com
3
Department of Otorhinolaryngology, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Fatemeh Sadat
Alavizadeh
moghimant921@mums.ac.ir
4
COPD Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Rahman
Movahed
rahmanmovahhed@gmail.com
5
Department of Otorhinolaryngology, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Parasto
Asnaashari
6
COPD Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Amir Mohammad hashem
Asnaashari
am_asnaashari@yahoo.com
7
COPD Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
LEAD_AUTHOR
1. Freid VM, Makuc DM, Rooks RN. Ambulatory health care visits by children: principal diagnosis and place of visit. National Center for Health Statistics. Vital Health Stat 13(137). 1998.
1
2. Asnaashari AMH, Talaei A, Baghban Haghighi M. Evaluation of Psychological Status in Patients with Asthma and COPD. Iran J Allergy Asthma Immunol 2012; 11:65–71.
2
3. Braunstahl GJ, Fokkens W. Nasal involvement in allergic asthma Allergy 2003;58:1235–43.
3
4. Asnaashari AMH, Rezaei S, Babaeian M, Taiarani M, Shakeri MT, Fatemi SS, et al. The effect of asthma on phonation: A controlled study of 34 patients: Ear Nose Throat J. 2012; 91:168–71.
4
5. Lugogo NL, Kraft M. Epidemiology of asthma: Clin Chest Med 2006,27(1):1-15
5
6. Krouse JH, Veling MC, Ryan MW, Pillsbury HC, Krouse HJ, Joe S, et al. Executive summary: asthma and the unified airway. Otolaryngol Head Neck Surg 2007; 136(5): 699–706.
6
7. Heidarnia MA, Entezari A, Moein M, Mehrabi Y, Pourpak Z. Prevalence of asthma symptom in Iran: a meta-analysis. Research in Medicine 2007; 31: 217–25.
7
8. Staikūniene J, Vaitkus S, Japertiene LM, Ryskiene S. Association of chronic rhinosinusitis with nasal polyps and asthma: clinical and radiological features, allergy and inflammation markers. Medicina (Kaunas). 2008; 44(4):257–65.
8
9. Ragab A, Clement P, Vincken W. Objective assessment of lower airway involvement in chronic rhinosinusitis. Am J Rhinol 2004;18:15–21.
9
10. Fan Y, Chen S, Qu X, Zuo K, Li X, Huang J, et al. A lower prevalence of asthma among patients with chronic rhinosinusitis in southern China. J Allergy Clin Immunol 2011;127:520–522.e1–5.
10
11. Yoshimura K, Kawata R, Haruna S, Moriyama H, Hirakawa K, Fujieda S, et al. Clinical epidemiological study of 553 patients with chronic rhinosinusitis in Japan. Allergol Int. 2011; 60: 491–6.
11
12. Seybt MW, McMains KC, Kountakis SE. The prevalence and effect of asthma on adults with chronic rhinosinusitis. Ear Nose Throat J. 2007; 86: 409–11.
12
13. Cookson JB. Prevalence rates of asthma in developing countries and their comparison with those in Europe and North America. Chest 1987; 91(6 Suppl):97S–103S.
13
14. Settipane GA, Chafee FH. Nasal polyps in asthma and rhinitis. A review of 6,037 patients. J Allergy Clin Immunol 1977; 59:17–21.
14
15. Baraniuk JN, White K. Chronic sinusitis subtypes and airway function. J Allerg Clin Immunol 2004;113:203.
15
16. Gu X, Ye P, Chen FY, Chen YL, Yang Y, Zhang LQ, et al. Clinical significance of pulmonary function test in patients with chronic rhinosinusitis with nasal polyps. Chinese Journal of Otorhinolaryn- gology Head and Neck Surgery 2013; 48(3):244–7.
16
17. Han DH, Kim SW, Cho SH, Kim DY, Lee CH, Kim SS, et al. Predictors of bronchial hyperrespon- siveness in chronic rhinosinusitis with nasal polyp Allergy 2009;64:118–22.
17
18. Watelet JB, Van Zele T, Brusselle G. Chronic cough in upper airway diseases. Respir Med 2010; 104: 652–7.
18
19.Wilkinson IA, Halliday JA, Henry RL, Hankin RG, Hensley MJ. Headache and asthma. J Paediatr Child Health 1994; 30: 253–6.
19
20. Lin DC, Chandra RK, Tan BK, Zirkle W, Conley DB, Grammer LC, et al. Association between severity of asthma and degree of chronic rhinosinusitis. Am J Rhinol Allergy 2011; 25: 205–8.
20
21. Pearlman AN, Chandra RK, Chang D, Conley DB, Tripathi-Peters A, Grammer LC, et al. Relationships between severity of chronic rhinosinusitis and nasal polyposis, asthma, and atopy. Am J Rhinol Allergy 2009; 23:145–8.
21
22. Tezer MS, Tahamiler R, Canakçioğlu S. Computed tomography findings in chronic rhinosinusitis patients with and without allergy. Asian Pac J Allergy Immunol 2006;24:123–7.
22
23. Erbek SS, Topal O, Erbek S, Cakmak O. Fungal allergy in chronic rhinosinusitis with or without polyps. Kulak Burun Bogaz Ihtis Derg 2008; 18:153–6.
23
24. Okayama M, Iijima H, Shimura S, Shimomura A, Ikeda K, Okayama H, et al. Methacholine bronchial hyperresponsiveness in chronic sinusitis. Respiration 1998;65:450–7.
24
25. Jarvis D, Newson R, Lotvall J, Hastan D, Tomassen P, Keil T et al. Asthma in adults and its association with chronic rhinosinusitis: the GA2LEN survey in Europe. Allergy 2012; 67(1): 91–8.
25
26. Gutman M, Torres A, Keen KJ, Houser SM. Prevalence of allergy in patients with chronic rhinosinusitis. Otolaryngol Head Neck Surg 2004; 130:545–52.
26
27.Rózańska-Kudelska M, Sieśiewicz A, Południewska B, Kania M, Michalczuk I, Rogowski M. Mold fungi and the role of allergy on fungi in chronic rhinosinusitis. Otolaryngol Pol 2009;63:245–8.
27
28. Leo G, Piacentini E, Incorvaia C, Consonni D, Frati F. Chronic rhinosinusitis and allergy. Pediatr Allergy Immunol 2007;18 Suppl 18:19–21.
28
ORIGINAL_ARTICLE
Sclerosing Mucoepidermoid Carcinoma of the Parotid Gland
Introduction: Mucoepidermoid carcinoma represents one of the most common malignant salivary gland tumors.However, the sclerosing morphologic variant is extremely rare with only 23 reported cases in the English-language literature since it was discovered in 1987. Case Report: Herein, we describe another case that was diagnosed in a 25-year-old woman presenting with a posterior auricular mass, as well as a review of the literature, which demonstrates that this is an extremely rare malignancy with no strict protocol for treatment. Conclusion: Pathologists must be aware of recognizing low grade sclerosing mucoepidermoid carcinoma which has metastatic potential and is frequently misdiagnosed as a benign lesion.
https://ijorl.mums.ac.ir/article_7037_de0bdb5927f25e004f391e2f413976c7.pdf
2016-07-01
281
285
10.22038/ijorl.2016.7037
Mucoepidermoid carcinoma
Sclerosing
Parotid gland
Farahnaz
Bidari Zerehpoosh
farahnazbidari@yahoo.com
1
Department of Pathology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AUTHOR
Bijan
Naghibzadeh
naghibzadehb@yahoo.com
2
Department of Otorhinolaryngology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AUTHOR
Elena
Jamali
elena.jamali@yahoo.com
3
Department of Pathology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
LEAD_AUTHOR
Moein
Jamali
moein.jamali@gmail.com
4
Department of Chemistry, Sharif University of Technology, Tehran, Iran.
AUTHOR
Amirali
Mafi
amirali.mafi@gmail.com
5
Department of Pathology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AUTHOR
Hooman
Bahrami Motlagh
hoomanbahrami@gmail.com
6
Department of Radiology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AUTHOR
1. Juan Rosai, Lauren V Ackerman. Rosai and Ackerman ‘s surgical pathology. 10th ed. Elsevier Inc; 2011: 831-2.
1
2. Fletcher CDM. Diagnostic Histopathology of Tumors. 3rd ed. Elsevier limited; 2007:275-9.
2
3. Tasaki T, Matsuyama A, Tabata T, Suzuki H, Yamada S, Sasaguri Y, et al. Sclerosing mucoepider- moid carcinoma with eosinophilia of the salivary gland: case report and review of the literature. Pathol Int 2013; 63(2):125-31.
3
4. Chan JKC, Saw D. Sclerosing mucoepidermoid tumour of the parotid gland: report of a case. Histopathology 1987; 11(2):203–7.
4
5. Kim H, Lee JH, Lee ES, Kwon SY, Kim TK, Kim YS. Sclerosing Mucoepidermoid Carcinoma of the Parotid Gland: A Case Report. The Korean J of Pathol 2007; 41: 193-7.
5
6. Fadare O, Hileeto D, Gruddin YL, Mariappan MR. Sclerosing mucoepidermoid carcinoma of the parotid gland. Arch Pathol Lab Med 2004;128(9):1046-9.
6
7. Cheuk W, Chan JKC. Salivary gland tumors. In: Fletcher CDM. (editor). Diagnostic Histopathology of Tumors. 2nd ed. London: Churchill Livingston; 2001: 231–311.
7
8. Muller S, Barnes L, Goodurn WJ.J. Sclerosing mucoepidermoid carcinoma of the parotid. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997; 83(6): 685–90.
8
9. Sinha S, Keogh IJ, Russell JD, Keane JCO. Sclerosing mucoepidermoid carcinoma of minor salivary gland: A case report. Histopathology 1999; 35: 283–4.
9
10. Urano M, Masato A, Yoshimune H, Makoto K. Sclerosing mucoepidermoid carcinoma with eosinophilia of the salivary glands. Pathol Res Pract 2002; 198(4): 305–10.
10
11. Ide F, Obara K, Enatsu K, Mishima K, Saito I. Sclerosing mucoepidermoid carcinoma of oral cavity. J Oral Pathol Med 2005; 34(3):187-9.
11
12. Heavner SB, Shah RB, Moyer JS. Sclerosing mucoepidermoid carcinoma of the parotid gland. Eur Arch Otorhinolaryngol 2006; 263: 955–9.
12
13. Veras EFT, Sturgis E, Luna MA. Sclerosing mucoepidermoid carcinoma of the salivary glands. Ann Diagn Pathol 2007; 11(6): 407–12.
13
14. Aguiar MC, Bernardes VF, Cardoso SV, Barbosa AA, Mesquita RA, Carmo MA. A rare case of sclerosing mucoepidermoid carcinoma arising in minor salivary glands with immunohistochemical evaluation. Minerva Stomatol 2008; 57(9): 453–7.
14
15. Shinhar SY. Sclerosing mucoepidermoid carcinoma of the parotid gland: case report. Ear Nose Throat J 2009 Nov; 88(11): E29-31.
15
16. Mendelson AA, al-Macki K, Chauvin P, Kost KM. Sclerosing mucoepidermoid carcinoma of the salivary gland: Case report and literature review. Ear Nose Throat J 2010; 89: 600–3.
16
17. Tian W, Yakirevich E, Matoso A, Gnepp DR. IgG4(+) plasma cells in sclerosing variant of mucoepidermoid carcinoma. Am J Surg Pathol 2012; 36(7): 973–9.
17
ORIGINAL_ARTICLE
Intraparotid Neurofibroma of the Facial Nerve: A Case Report
Introduction: Intraparotid neurofibromas of the facial nerve are extremely rare and mostly associated with neurofibromatosis type 1 (NF1). Case Report: This is a case of a healthy 40-year-old man, which underwent surgery for a preoperatively diagnosed benign parotid gland lesion. After identification of the facial nerve main trunk, a single large mass (6 x 3 cm) incorporating the upper nerve division was observed. The nerve portion involved in the mass could not be dissected and was inevitably sacrificed with immediate neuroraphy of the upper division of the facial nerve with 6/0 prolene. The final histopathology revealed the presence of a neurofibroma. Complete left side facial nerve paralysis was observed immediately postoperatively but the function of the lower half was returned within 4 months and the upper half was returned after 1 year. Currently, after 3 years of follow up, there are no signs of recurrence and normal facial nerve function is observed. Conclusion: Neurofibroma should be considered as the diagnosis in a patient demonstrating a parotid mass. In cases where it is diagnosed intraoperatively, excision of part of the nerve with the mass will be inevitable though it can be successfully repaired by end to end anastomosis.
https://ijorl.mums.ac.ir/article_7038_a769955bb396df9b6d4a78668dc0f6c2.pdf
2016-07-01
287
290
10.22038/ijorl.2016.7038
Facial Nerve
Parotid gland
Neurofibroma
Ahmed
Nofal
dr.ahmed.nofal@gmail.com
1
Department of Otorhinolaryngology , Faculty of Medicine, Zagazig University, Egypt.
LEAD_AUTHOR
Mohammad
El-Anwar
mwenteg@yahoo.com
2
Department of Otorhinolaryngology , Faculty of Medicine, Zagazig University, Egypt.
AUTHOR
1. Chiang C W, Chang Y L, Lou P J. Multicentricity of intraparotid facial nerve schwannomas. Annals of Otology Rhinology and Laryngology 2001; 110(9): 871-4.
1
2. Marchioni D, Ciufelli MA, Presutti L. Intraparotid facial nerve schwannoma: literature review and classification proposal. The Journal of Laryngology & Otology 2007; 121(08): 707-12.
2
3. Sullivan MJ, Babyak JW, Kartush JM. Intraparotid facial nerve neurofibroma.The Laryngoscope 1987; 97(2): 219-23.
3
4. Neely J G. Neoplastic involvement of the facial nerve. Otolaryngologic clinics of North America 1974; 7(2): 385-6.
4
5. Hehar SS, Dugar J, Sharp J. The changing faces of a parotid mass. The Journal of Laryngology & Otology 1999; 113(10): 938-41.
5
6. Kavanagh KT, Panje WR. Neurogenic neoplasms of the seventh cranial nerve presenting as a parotid mass.American journal of otolaryngology 1982; 3(1): 53-6.
6
7. Balle VH, Greisen O. Neurilemmomas of the facial nerve presenting as parotid tumors.The Annals of otology, rhinology, and laryngology 1983; 93(1 Pt 1): 70-2.
7
8. Conley J, Janecka I. Neurilemmoma of the facial nerve. Plastic and reconstructive surgery 1973; 52(1): 55-9.
8
9. Pulec JL. Symposium on ear surgery. II. Facial nerve neuroma. The Laryngoscope 1972; 82(7): 1160-76.
9
10. Kavanagh KT, Panje WR. Neurogenic neoplasms of the seventh cranial nerve presenting as a parotid mass.American journal of otolaryngology 1982; 3(1): 53-6.
10
11. Gutmann DH, Collins FS. The neurofibromatosis type 1 geneand its protein product, neurofibromin. Neuron 1993; 10(3):335-43
11
12. McGuirt WF, Johnson PE, McGuirt WT. Intraparotid facial nerve neurofibromas. The Laryngoscope 2003; 113(1): 82-4.
12
13. Prasad S, Myers EN, Kamerer DB, Demetrsis AJ. Neurilemmoma(schwannoma) presenting as a parotid mass. OtolHead Neck Surg 1993; 108(1):76–9.
13
14. Kumar BN, Walsh RM, Walter NM, Tse A, Little JT. Intraparotid facial nerve schwannoma in a child. The Journal of Laryngology & Otology 1996; 110(12): 1169-70.
14
15. Sellars SL. Neurofibroma of the facial nerve. South African medical journal=Suid-Afrikaansety- dskrifvirgeneeskunde 1972; 46(37): 1332-4.
15
16. Saleh E, Achilli V, Naguib M, Taibah AK, Russo A, Sanna M, Mazzoni A. Facial nerve neuromas: diagnosis and management. Otology &Neurotology 1995; 16(4): 521-6.
16
17. Albernaz MS, Pratt MF, Garen PD. Intraparotid facial nerve neurofibroma: a case report and literature review. Otolaryngology--Head and Neck Surgery 1990; 102(4): 413-15.
17
18. Kumar A, Ranjan R, Kumar S, Radder S, Rana RS, Bhagat S. Intra-parotid neurofibroma of facial nerve: a case report. International Journal of Medical Research & Health Sciences 2013; 2(3): 716-18.
18
ORIGINAL_ARTICLE
Unusually Giant Sublingual Epidermoid Cyst: A Case Report
Introduction: Epidermoid cysts are rare, slow‑growing, benign, developmental cysts, which are derived from abnormally situated ectodermal tissue. Epidermoid cysts of the floor of the mouth represent <0.01% of all oral cysts. So far, only a few cases have been reported. Case Report: Hereby, we present a case of a giant sublingual epidermoid cyst, which was completely asymptomatic upon presentation. However, due to its large size, it pushed the epiglottis posteriorly and created difficulty during intubation. The patient developed respiratory distress after its surgical excision and extubation, requiring tracheostomy post operatively. The patient recovered well and a successful weaning of tracheostomy was performed, giving the patient a healthy life. Conclusion: Epidermoid cyst is a rare differential diagnosis of sublingual swelling that should be kept in mind for large asymptomatic swellings in this region. The only symptom it can cause might be respiratory distress due to its large size. This can happen not only pre-operatively but also post-operatively and the surgeon should be ready for immediate tracheostomy.
https://ijorl.mums.ac.ir/article_7039_fd10706e4873f3ca8944521b82f6b83a.pdf
2016-07-01
291
296
10.22038/ijorl.2016.7039
Epidermal Cyst
Intubation
Sublingual
Surgery
Tracheostomy
Chintan
Nishar
stars.chin@gmail.com
1
Department of Otorhinolaryngology, Dr. Shankarrao Chavan Govt. Medical College, Nanded, India.
LEAD_AUTHOR
Atish
Gujrathi
stars_chin@yahoo.co.in
2
Department of Otorhinolaryngology, Dr. Shankarrao Chavan Govt. Medical College, Nanded, India.
AUTHOR
Vijayalaxmi
Ambulgekar
hodent.gmcn@gmail.com
3
Department of Otorhinolaryngology, Dr. Shankarrao Chavan Govt. Medical College, Nanded, India.
AUTHOR
Pravin
Chavan
pravin_4155@yahoo.co.in
4
Department of Otorhinolaryngology, Dr. Shankarrao Chavan Govt. Medical College, Nanded, India.
AUTHOR
1. Shafer WG, Hine MK, Levy BM. A Text Book of Oral Pathology. 4th ed. Philadelphia: WB Saunders; 1993. p. 67.
1
2. Calderon S, Kaplan I. Concomitant sublingual and submental epidermoid cysts: a case report. J Oral Maxillofac Surg. 1993; 51:790–2.
2
3. Cortezzi W, De Albuquerque EB. Secondarily infected epidermoid cyst in the floor of the mouth causing a life threatening situation. J Oral Maxillofac Surg. 1994; 52:762–4.
3
4. Worley CM, Laskin DM. Coincidental sublingual and submental epidermoid cyst. J Oral Maxillofac Surg. 1993;51: 787–90.
4
5. De Ponte FS, Brunelli A, Marchetti E, Bottini DJ. Sublingual epidermoid cyst. J Craniofac Surg. 2002; 13(2):308–10.
5
6. Gold BD, Sheinkonf DE, Levy B. Dermoid, Epidermoid and teratoid cysts of the tongue and the floor of the mouth. J Oral Surg. 1974; 32:107.
6
7. Yoshinari M, Nagayama M. Epidermoid cyst of the uvula. J Oral Maxillofac Surg. 1986; 44:828–9.
7
8. Zachariades N, Skoura-Kafoussia C. A life threatening epidermoid cyst of the floor of the mouth: report of a case. J Oral Maxillofac Surg. 1990; 48: 400–3.
8
9. Howell CJT. The sublingual dermoid cyst. Oral Surg Oral Med Oral Pathol. 1985; 59:578–80.
9
10. Coit WE, Harnsberger HR, Osborn AG, Smoker WR, Stevens MH, Lufkin RB. Ranulas and their mimics: CT evaluation. Radiology 1987; 163:211-6.
10
11. Longo F, Maremonti P, Mangone GM, De Maria G, Califano L. Midline (dermoid) cysts of the floor of the mouth: report of 16 cases and review of surgical techniques. Plast Reconstr Surg 2003; 112(6): 1560–5.
11
12. Damle MV, Irani DK, Hiranandani NL. Epidermoid cyst of the floor of the mouth. Case report. Bombay Hosp J 2002;44:267‑70.
12
13. Hemaraju N, Nanda SK, Medikeri SB. Sub‑lingual dermoid cyst. Indian J Otolaryngol Head Neck Surg 2004;56:218‑20.
13
14. Shear M. Cyst of the oral regions. 3rd ed. Wright, Oxford; 1992: 196–208.
14
15. Walstad William R, Solomon James M, Schow Sterling R, Ochs Mark W. Midline cystic lesion of the floor of the mouth. J Oral Maxillofacial Surg 1998; 56:70–4.
15
16. Jham BC, Duraes GV, Jham AC, Santos CR. Epidermoid cyst of the floor of the mouth: a case report. J Can Dent Assoc. 2007 Jul-Aug;73(6):525-8.
16
17. Ikeda I, Ono T. Basal cell carcinoma originating from an epidermoid cyst. J Dermatol 1990; 17:643–6.
17
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ORIGINAL_ARTICLE
Treatment Approach for Maxillary Hypoplasia in Cleft Patients: Class III Elastics with Skeletal Anchorage (Report of Two Cases)
Introduction: Treatment ofcleft lip and palate patients requires a multidisciplinary plan. These patients usually have a hypoplastic maxilla due to the prior surgical scars. Orthognathic surgery to advance the maxilla in these patients is not very efficient; therefore, orthopedic interventions during an appropriate age seems to be essential. Case Report: In this article, two cleft lip and palate patients have been treated with Class III elastics anchored to the maxillary posterior and mandibular anterior miniplates in order to induce maxillary advancement. Conclusion: Both cases showed a significant improvement in their profiles with minimal dentoalveolar compensations. A counterclockwise rotation of the mandible occurred.
https://ijorl.mums.ac.ir/article_7043_7f3030fd6b1baf05dd3fb6b54d7a3b08.pdf
2016-07-01
297
302
10.22038/ijorl.2016.7043
Cleft lip and palate
Skeletal anchorage
Maxillary advancement
Arezoo
Jahanbin
jahanbina@mums.ac.ir
1
Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Mojgan
Kazemian
kazemianm@mums.ac.ir
2
Oral and Maxillary Diseases Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Iman
Saeedi Pouya
dr.saeedipouya@gmail.com
3
Department of Orthodontics, Mashhad University of Medical Sciences, Mashhad, Iran.
LEAD_AUTHOR
Neda
Eslami
eslamin@mums.ac.ir
4
Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Hooman
Shafaee
shafaeeh@mums.ac.ir
5
Oral and Maxillofacial Diseases Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
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