TY - JOUR ID - 6031 TI - Inflammatory Myofibroblastic Tumor of the Larynx: A Case Report JO - Iranian Journal of Otorhinolaryngology JA - IJORL LA - en SN - 2251-7251 AU - Izadi, Farzad AU - Ghanbari, Hadi AU - Azizi, Mohammad AU - Gasembaglou, Shahram AU - Manteghi, Mohammad Javad AU - Ghanbari, Azadeh AD - Department of Otorhinolaryngology, Hazart Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran. AD - ENT & HNS Research Center, Hazart Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran. AD - Pathologist, Shahriyar Hospital, Tehran, Iran. AD - General practitioner, Iran University of Medical Sciences, Tehran, Iran. AD - College of Dentistry, Ajman University of Science and Technology, Ajman, UAE. Y1 - 2016 PY - 2016 VL - 28 IS - 1 SP - 79 EP - 82 KW - Head and neck tumor KW - Immunohistochemstry (IHC) KW - Inflammatory myofibroblastic tumor KW - Larynx KW - laryngeal pseudotumor KW - Laryngeal mass DO - 10.22038/ijorl.2016.6031 N2 - Introduction: Inflammatory myofibroblastic pseudotumors are initially described in the lung and various extrapulmonary sites such as the orbits, palatine tonsils, ears, gingiva, pterygomaxillary space, and periodontal tissues. These tumors rarely involve the larynx and predilection to the glottis occurs in an indolent manner.   Case Report This case describes a laryngeal myofibroblastic tumor in a 46-year-old woman who presented with an aggressive tumor that extended to the floor of the mouth and the base of the tongue. Extended supraglottic laryngectomy was undertaken for the patient. The diagnosis was spindle cell proliferation with dense lymphoplasma cell infiltration compatible with inflammatory myofibroblastic tumor (Inflammatory pseudotumor or plasma cell granuloma). Definitive diagnosis was achieved with immunohistochemical (IHC) staining.   Conclusion:  We believe that further IHC studies are required to define the true nature of these tumors especially for those that behave in an aggressive pattern. UR - https://ijorl.mums.ac.ir/article_6031.html L1 - https://ijorl.mums.ac.ir/article_6031_e9912cc47530643cecb522c9fbb51478.pdf ER -