Effect of Botulinum Neurotoxin A Injection into the Submucoperichondrium of the Nasal Septum in Reducing Idiopathic Non-Allergic Rhinitis and Persistent Allergic Rhinitis
Keramat
Mozafarinia
Department of Otorhinolaryngology, Medical School, Kerman University of Medical Sciences and Health Services, Kerman, Iran.
author
Mehdi
Abna
Department of Otorhinolaryngology, Medical School, Kerman University of Medical Sciences and Health Services, Kerman, Iran.
author
Narges
khanjani
Neurology Research Center, Shafa Hospital, Kerman University of Medical Sciences and Health Services, Kerman, Iran.
author
text
article
2015
eng
Introduction: Submucoperichondrial injection of botulinum neurotoxin A (BTA) in the nasal septum is a promising therapeutic option in the treatment of persistent allergic rhinitis (AR) and non-allergic rhinitis, and is safer and more effective than intraturbinate injection in reducing clinical symptoms. Materials and Methods: Forty patients diagnosed with persistent AR or non-allergic rhinitis referred to Shafa Medical Center affiliated to Kerman University of Medical Sciences were included in this study and were randomly allocated to the intervention or control groups. Patients received an injection of 80 units BTA (Dysport, Ipsen Ltd Company, UK) at a concentration of 200 mU/ml in normal saline on four spots in each side of the nose and were followed for 12 weeks. Data were analyzed using a chi-square or Fisher’s test, and Mann Whitney U test. Results: The mean age of patients was 46.1±15.3 years, and the two groups did not differ significantly in demographic variables. The severity of rhinitis symptoms was reduced after 4 weeks of injections in the intervention group and then gradually decreased further until the 12th week. There was a statistically significant difference between the groups (P<0.05). No adverse effects were reported. Conclusion: Submucoperichondrial BTA injection can be considered an effective therapeutic option in patients with persistent AR and idiopathic rhinitis. In comparison with other injection techniques, submucoperichondrial BTA injection has fewer side effects with a longer period of effectiveness, and is easy to perform and is more tolerable for the patient.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
27
v.
4
no.
2015
253
259
https://ijorl.mums.ac.ir/article_4514_c4880633b48725fd2f169d685c0191d1.pdf
dx.doi.org/10.22038/ijorl.2015.4514
Allergic Rhinitis in Adults with Chronic Suppurative Otitis Media
Shadman
Nemati
Sinonasal Diseases Research Centre, Amiralmomenin Hospital, Guilan University of Medical Sciences, Rasht, Iran.
author
Reza
Jafari Shakib
Department of Immunology, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
author
Maryam
Shakiba
PhD Candidate, Department of Epidemiology, School of Public Health, Shahid Beheshti University of medical sciences, Tehran, Iran.
author
Nematollah
Araghi
Department of Otolaryngology, Amiralmomenin Hospital, Guilan University of Medical Sciences, Rasht, Iran.
author
Seyyede Zeinab
Azimi
Sinonasal Diseases Research Centre, Amiralmomenin Hospital, Guilan University of Medical Sciences, Rasht, Iran.
author
text
article
2015
eng
Introduction: Chronic suppurative otitis media (CSOM) is considered one of the most common causes of acquired hearing impairment in developing countries. CSOM is a multifactorial persistent inflammatory disease of the middle ear. A distinct pathophysiologic mechanism linking allergic rhinitis (AR) and CSOM remains to evolve. The purpose of this study was to investigate the association between AR and CSOM in adults.This was a case-control study. Materials and Methods: The subjects were 62 adults (23 male, 39 female) with established CSOM and 61 healthy controls.CSOM was diagnosed when there was a history of chronic (persisting for at least 3 months) otorrhea, accumulation of mucopurulent exudates in the external auditory canal or middle ear and/or perforated tympanic membrane on otoscopy. All participants were evaluated for the presence of AR by clinical evaluation of allergic symptoms, and underwent a skin-prick test for 23 common regional allergens. Statistical analysis was performed using SPSS version 16. Results: The prevalence of clinical rhinitis (allergic and non-allergic) was significantly higher among the cases compared with controls (62.5% vs. 37.5%, P=0.02). The prevalence of AR (proven by positive skin-prick test) was also significantly higher among affected adults than controls (24.6% and 13.8%, respectively). Adjusting for age, a logistic regression model showed that there was a significant difference between the two groups. Patients with AR and non-AR were at 3.27- (95% CI=1.15–9.29; P=0.036) and 2.57-(95% CI=1.01–6.57; P=0.048) fold increased risk of developing CSOM, respectively, compared with healthy individuals. Conclusion: The study showed a higher prevalence of AR in CSOM patients than in controls. It may be valuable to evaluate and control this factor in these patients.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
27
v.
4
no.
2015
261
266
https://ijorl.mums.ac.ir/article_4518_aafef35062a16bfa779a5f0629704a9b.pdf
dx.doi.org/10.22038/ijorl.2015.4518
Effect of Ascorbic Acid on Noise Induced Hearing Loss in Rats
Ziba
Loukzadeh
Industrial Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
author
Abolfazl
Hakimi
Industrial Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
author
Mansour
Esmailidehaj
Department of Physiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
author
Amir Houshang
Mehrparvar
Industrial Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
author
text
article
2015
eng
Introduction: After presbycusis, noise-induced hearing loss is the second most common cause of acquired hearing loss. Numerous studies have shown that high-intensity noise exposure increases free radical species; therefore, use of antioxidants to detoxify the free radicals can prevent cellular damage in the cochlea. We studied the potential hearing protective effect of different doses of ascorbic acid administered prior to noise exposure in rats. Materials and Methods: Twenty-four male albino Wistar rats were randomly allocated into four groups: groups A, B, and C received 1250, 250, and 50 mg/kg/day of ascorbic acid, respectively, and group D acted as the control group. After 14 days of ascorbic acid administration, the rats were exposed to noise (105 dB sound pressure level for 2 h). Distortion product otoacoustic emissions (DPOAE) were recorded prior to starting the ascorbic acid as baseline and 1 h after the noise exposure. Results: The amplitude decrease was 14.99 dB for group A, 16.11 dB for group B, 28.82 dB for group C, and 29.91 dB for the control group. Moderate and high doses of ascorbic acid significantly reduced the transient threshold shift in the rats. Conclusion: The results of present study support the concept of cochlea protection by antioxidant agents. This dose-dependent protective effect was shown through the use of ascorbic acid treatment prior to noise exposure.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
27
v.
4
no.
2015
267
272
https://ijorl.mums.ac.ir/article_4515_7f3294fcbcfaa34ab51277657a50f75b.pdf
dx.doi.org/10.22038/ijorl.2015.4515
Comparative Study of Hearing Impairment among Healthy and Intensive Care unit Neonates in Mashhad, North East Iran
Ahmadshah
Farhat
Neonatal Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Mohammad Mahdi
Ghasemi
Sinus and Surgical Endoscopic Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Javad
Akhondian
3Department of Pediatrics, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Ashraf
Mohamadzadeh
Neonatal Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Habibollah
Esmaeili
Neonatal Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Rana
Amiri
Neonatal Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Ali Asqar
Raoof Saeb
Audiologist, Member of Khorasan Cochlear Implant, Mashhad, Iran.
author
Mohammad Reza
Tale
Sinus and Surgical Endoscopic Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Faezeh
Madani Sani
Medical Student(Intern), Department of Pediatrics, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
author
text
article
2015
eng
Introduction: According to World Health Organization (WHO) 2001 statistics, hearing disorders are the most common congenital disease, and the incidence rate among high-risk newborns is as much as ten times as high as that in healthy neonates. However, 78% of screening test failures are well-baby nursery babies. The Joint Committee on Infants’ Hearing (JCIH) has emphasized the importance of early diagnosis and treatment in neonates with hearing impairments in order to preserve their maximum linguistic skills. The aim of our study was to compare the prevalence of hearing loss among babies in the neonatal intensive care unit (NICU) and the rooming-in unit (RIU), and study their risk factors. Materials and Methods: Neonates born in three hospitals in Mashhad between 2008 to 2010 were studied prospectively and screened for auditory disorders using the oto acoustic emission (OAE) test at the time of discharge and 3 weeks later. To confirm hearing loss, the auditory steady state response (ASSR) test was used among those participants who failed both OAE tests. Results: Two-thousand and sixty-three neonates from the NICU were screened and compared with a control group consisting of 8,724 neonates from the RIU or the well-baby nursery. At the end of the study, hearing impairment as confirmed by failure in the ASSR test was diagnosed in 31 neonates (26 in the control group [0.30%] and five in the NICU group [1.94%]). Conclusion: In our study, the prevalence of hearing disorders among NICU neonates was 6.5-times greater than that among babies from the RIU or well-baby unit. This observation demonstrates the importance of universal screening programs particularly for high-risk population neonates.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
27
v.
4
no.
2015
273
277
https://ijorl.mums.ac.ir/article_4517_a3dc9c01347e4075abce39e155c59a8b.pdf
dx.doi.org/10.22038/ijorl.2015.4517
The Effect of Neoadjuvant Therapy on Early Complications of Esophageal Cancer Surgery
Mohammadtaghi
Rajabi Mashhadi
Endoscopic & Minimally Invasive Surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Reza
Bagheri
Cardio-Thoracic Surgery & Transplant Research Center, Emam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Abbas
Abdollahi
Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Mohammad Javad
Ghamari
Endoscopic & Minimally Invasive Surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
soudabeh
shahidsales
Department of Radiotherapy & oncology, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Maryam
Salehi
Department of Community Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Reza
Shahkaram
Endoscopic & Minimally Invasive Surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Mohamad Reza
Majidi
Sinus and Surgical Endoscopic Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Shima
Sheibani
Cardio-Thoracic Surgery & Transplant Research Center, Emam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
text
article
2015
eng
Introduction: Early diagnosis and appropriate treatment is required in esophageal cancer due to its invasive nature. The aim of this study was to evaluate early post-esophagectomy complications in patients with esophageal cancer who received neoadjuvant chemoradiotherapy (NACR). Materials and Methods: This randomized clinical trial was carried out between 2009 and 2011. Patients with lower-third esophageal cancer were randomly assigned to one of two groups. The first group consisted of 50 patients receiving standard chemoradiotherapy (Group A) and then undergoing surgery, and the second group consisted of 50 patients undergoing surgery only (Group B). Patients were evaluated with respect to age, gender, clinical symptoms, type of pathology, time of surgery, perioperative blood loss, and number of lymph nodes resected as well as early post-operative complicate including leakage at the anastomosis site, chylothorax and pulmonary complications, hospitalization period, and mortality rate within the first 30 days after surgery. Results: The mean age of patients was 55 years. Seventy-two patients had squamous cell carcinoma (SCC) and 28 patients had adenocarcinoma (ACC). There was no significant difference between the two groups with respect to age, gender, time of surgery, complications including anastomotic leakage, chylothorax, pulmonary complications, cardiac complications, deep venous thrombosis (DVT), or mortality. However, there was a significant difference between the two groups regarding hospital stay, time of surgery, perioperative blood loss, and number of lymph nodes resected. Conclusion: The use of NACR did not increase early post-operative complications or mortality among patients with esophageal cancer.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
27
v.
4
no.
2015
279
284
https://ijorl.mums.ac.ir/article_4247_6b450631560dbcdf675037956258783c.pdf
dx.doi.org/10.22038/ijorl.2015.4247
Intra-Operative Lymphatic Mapping and Sentinel Node Biopsy in Laryngeal Carcinoma: Preliminary Results
Ehsan
Khadivi
Sinus and Surgical Endoscopic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
author
Maryam
Daghighi
Sinus and Surgical Endoscopic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
author
Kamran
Khazani
Sinus and Surgical Endoscopic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
author
Vahid Reza
Dabbagh Kakhki
Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
author
Leili
Zarifmahmoudi
Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
author
Ramin
Sadeghi
Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
author
text
article
2015
eng
Introduction: Sentinel node mapping has been used for laryngeal carcinoma in several studies, with excellent results thus far.In the current study, we report our preliminary results on sentinel node mapping in laryngeal carcinoma using intra-operative peri-tumoral injection of a radiotracer. Materials and Methods: Patients with biopsy-proven squamous cell carcinoma of the larynx were included in the study. Two mCi/0.4 cc Tc-99m-phytate in four aliquots was injected on the day of surgery, after induction of anesthesia, in the sub-mucosal peri-tumoral location using a suspension laryngoscopy. After waiting for 10 minutes, a portable gamma probe was used to search for sentinel nodes. All patients underwent laryngectomy and modified radical bilateral neck dissection. All sentinel nodes and removed non-sentinel nodes were examined by hematoxylin and eosin (H&E) staining. Results: Ten patients with laryngeal carcinoma were included. At least one sentinel node could be detected in five patients (bilateral nodes in four patients). One patient had pathologically involved sentinel and non-sentinel nodes (no false-negative cases). Conclusion: Sentinel node mapping in laryngeal carcinoma is technically feasible using an intra-operative radiotracer injection. In order to evaluate the relationship of T-stage and the laterality of the tumor with accuracy, larger studies are needed.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
27
v.
4
no.
2015
285
291
https://ijorl.mums.ac.ir/article_4418_9d0121d15a31d081dfa0a3d316a745ba.pdf
dx.doi.org/10.22038/ijorl.2015.4418
Deep Neck Space Infections: A Study of 76 Cases
Gaurav
Kataria
Department of Otorhinolaryngology, SGRDIMSR, Amritsar, Punjab, India.
author
Aditi
Saxena
Department of Pathology, GMC, Amritsar, Punjab, India.
author
Sanjeev
Bhagat
Department of Otorhinolaryngology, GMC, Patiala, Punjab, India.
author
Baldev
Singh
Department of Otorhinolaryngology, GMC, Patiala, Punjab, India.
author
Manpreet
Kaur
Department of Otorhinolaryngology, GMC, Patiala, Punjab, India.
author
Gurpreet
Kaur
Department of Otorhinolaryngology, GMC, Patiala, Punjab, India.
author
text
article
2015
eng
Introduction: Deep neck space infections (DNSI) are serious diseases that involve several spaces in the neck. The common primary sources of DNSI are dental infections, tonsillar and salivary gland infections, malignancies, and foreign bodies. With widespread use of antibiotics, the prevalence of DNSI has been reduced. Common complications of DNSI include airway obstruction, jugular vein thrombosis, and sepsis. Treatment principally comprises airway management, antibiotic therapy, and surgical intervention. This study was conducted to investigate the age and sex distribution of patients, symptoms, presentation, sites involved, bacteriology, and management and complications of DNSI. Materials and Methods: This retrospective study was performed from October 2010 to January 2013, and included 76 patients with DNSI. Patients of all age groups and gender were included. All parameters including age, gender, co-morbidities, presentation, site, bacteriology, complications, and required interventions were studied. Results: In our study, the majority of patients were in the 31–50-year age group. Males accounted for 55.26% of the sample and females for 44.74%, with a male:female ratio of 1.23. Most of the patients were from a rural background. Diabetes was found as a co-morbid condition in 10.52% cases. Neck pain was the most common symptom, identified in 89.47% cases. The most common etiological factor was odontogenic infection (34.21%), followed by tonsillar and pharyngeal infection (27.63%). The most common presentation was Ludwig’s angina (28.94%), followed by peritonsillar abscess and submandibular abscess. In 50% of cases, Streptococcus and Staphylococcus were found in the culture. Surgical intervention was carried out in 89.47% cases. Emergency tracheotomy was required in 5.26% cases. Conclusion: DNSI can be life-threatening in diabetic patients, the immunocompromised, and elderly patients, and special attention should therefore be given to these groups. Early diagnosis and treatment is essential to prevent complications. All patients must be treated initially with intravenous antibiotics, with treatment subsequently updated based on a culture and sensitivity report. Due to poor oral hygiene, lack of nutrition, smoking and chewing of beetle nut and tobacco, odontogenic infections are the most common cause of DNSI. Thus, DNSI could be prevented by making the population aware of dental and oral hygiene and offering regular check-ups for dental infections.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
27
v.
4
no.
2015
293
299
https://ijorl.mums.ac.ir/article_4520_6a974d9bce8886ae76b36f2d55285140.pdf
dx.doi.org/10.22038/ijorl.2015.4520
The Effect of Smoking on Mineral and Protein Composition of Saliva
Ali
Fattahi Bafghi
Department of Otorhinolaryngology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
author
ali
goljanian
Department of Otorhinolaryngology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
author
Peyman
Bakhshayi Sharbabaki
Department of Otorhinolaryngology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
author
text
article
2015
eng
Introduction:
To assess the salivary composition of proteins and minerals in smokers compared with non-smokers.
Materials and Methods:
In this study we compared the total protein and Ca, Na, K, Mg, Pb of whole saliva in two groups of men (28 smokers and 31nonsmokers) aged between 29-41years.
Results:
Fifty-nine participants were evaluated. The mean age was 33.14±5.32 years among smokers and 32.15±5.12 years among non-smokers (P>0.05). The mean concentration of total protein, Ca, Pb,and Zn of whole saliva in smokers was lower than that in non-smokers, but the difference was not statistically significant (P>0.05). The mean concentration of Na, K, Mg in whole saliva was not significantly different between smokers and non-smokers (P>0.05).
Conclusion:
We specified that smoking reduced the value of total protein, Ca and Pb of saliva, however it did not havean impact on Na, K, and Mg of saliva.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
27
v.
4
no.
2015
301
305
https://ijorl.mums.ac.ir/article_3818_ccf2dcbf95a23b9ed2c6e61e644d7d2d.pdf
dx.doi.org/10.22038/ijorl.2015.3818
Solitary Fibrous Tumor of Nasal Cavity:A Case Report
George
Mathew
Department of Otorhinolaryngology, Christian medical college ,Vellore ,Tamil Nadu, India.
author
Gaurav
ashish
Department of Otorhinolaryngology, Christian medical college ,Vellore ,Tamil Nadu, India.
author
Amit Kumar
Tyagi
Department of Otorhinolaryngology, Christian medical college ,Vellore ,Tamil Nadu, India.
author
Ramanathan
Chandrasekharan
Department of Otorhinolaryngology, Christian medical college ,Vellore ,Tamil Nadu, India.
author
Roshna Rose
Paul
Department of Otorhinolaryngology, Christian medical college ,Vellore ,Tamil Nadu, India.
author
text
article
2015
eng
Introduction: Solitary fibrous tumours (SFTs) of the nose and paranasal sinuses are extremely rare.These were originally described as neoplasms of the pleura originating from spindle cells. It is further sub-classified as a benign type of mesothelial tumour. Its occurrence in many extra pleural sites have been reported earlier, mainly in the liver, parapharyngeal space, sublingual glands, tongue, parotid gland, thyroid, periorbital region, and very occasionally in the nose and paranasal sinus area. Case Report: A 28-year-old man with a 6 month history of persistent progressive left nasal obstruction and watering of the left eye is reported. Further imaging by CT and MRI revealed a large, left-sided, highly vascular, nasal cavity mass (Fig 1,2,3,4) pushing laterally on the medial wall of the maxilla. The patient underwent a lateral rhinotomy, which proceeded with the excision of the mass. Histopathological analysis of the specimen was consistent with SFT. Conclusion: This case is reported to develop insights regarding diagnosis and management of such rare tumours.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
27
v.
4
no.
2015
307
312
https://ijorl.mums.ac.ir/article_4242_5ac2a6a290a4ca7172fed4d810fa202f.pdf
dx.doi.org/10.22038/ijorl.2015.4242
Radioresistant Extramedullary Plasmacytoma of the Maxillary Sinus: A Case Report and review article
Matin
Ghazizadeh
Department of Otorhinolaryngology, Head and Neck Surgery, Taleghani Hospital,Shahid Beheshti University of Medical Sciences, Tehran, Iran.
author
Hesamodin
Alavi Amlashi
Department of Otorhinolaryngology, Head and Neck Surgery, Taleghani Hospital,Shahid Beheshti University of Medical Sciences, Tehran, Iran.
author
golfam
mehrparvar
Department of Otorhinolaryngology, Head and Neck Surgery, Taleghani Hospital,Shahid Beheshti University of Medical Sciences, Tehran, Iran.
author
text
article
2015
eng
Introduction: Plasmacytoma is a monoclonal proliferation of plasma cells. It can be an isolated lesion, for which the term extramedullary plasmacytoma is used, or a representation of multiple myeloma.The upper respiratory tract is the most common site for an extramedullary plasmacytoma. Sinonasal plasmacytomas cause different symptoms depending on the sites of origins and the areas of involvement. The treatment of choice for extramedullary plasmacytoma is local radiotherapy. Although it is generally accepted that plasmacytomas are radiosensitive, there are reports of cases that do not respond to radiotherapy. Case Report: A case of a 24-year-old male diagnosed with radioresistant extramedullary plasmacytoma of the maxillary sinus, who responded to surgical treatment, is reported. Conclusion: It is reasonable to consider an interdisciplinary approach in the management of extramedullary plasmacytoma. Considering early surgical intervention in cases encompassing risk factors of radiotherapy resistance is especially recommended before debilitating complications emerge.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
27
v.
4
no.
2015
313
318
https://ijorl.mums.ac.ir/article_4245_0ba92c4f6a3274e553139ecffb99937f.pdf
dx.doi.org/10.22038/ijorl.2015.4245
Inflammatory Septal Nasal Polyp
Neha
Salaria
Department of Otorhinolaryngology, BPS Government Medical College for Women, Khanpur Kalan, Haryana, India.
author
Naveen
Sharma
Department of Otorhinolaryngology, BPS Government Medical College for Women, Khanpur Kalan, Haryana, India.
author
Uma
Garg
Department of Otorhinolaryngology, BPS Government Medical College for Women, Khanpur Kalan, Haryana, India.
author
Swaran
Saluja
Department of Pathology, BPS Government Medical College for Women, Khanpur Kalan, Haryana, India.
author
Ruchi
Agarwal
Department of Pathology, BPS Government Medical College for Women, Khanpur Kalan, Haryana, India.
author
text
article
2015
eng
Introduction:
Nasal polyps are benign prolapsed mucosal lesions which commonly arise from the paranasal sinuses and lateral walls of the nose especially the contact areas of osteomeatal complex. Though nasal polyps arising from the nasal septum have been reported, those arising from its anterior part are extremely rare and present a diagnostic dilemma. Aetiology is multifactorial and is mainly a result of the inflammatory response of the lining mucosa.
Case Report:
The case of a 28-year-old male, with a history of progressively increasing nasal complaints since 4 months and with a nasal mass arising from the anterior nasal septum on examination, is reported. Diagnosis of an inflammatory nasal polyp was made on histopathological examination after surgical excision of the mass.
Conclusion:
The diagnosis of an inflammatory nasal polyp was not only unusual in terms of its location but also in its appearance on anterior rhinoscopy and tomographic scanning images. The definitive diagnosis in such cases can only be achieved through surgical resection and detailed histopathological examination.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
27
v.
4
no.
2015
319
323
https://ijorl.mums.ac.ir/article_4244_2da458dd21b895707541253381dd0e51.pdf
dx.doi.org/10.22038/ijorl.2015.4244
Cartilaginous Choristoma of the Tonsil: Three Case Reports
Recep
Bedir
Department of Pathology, Recep Tayyip Erdogan University of Medical Faculty, Rize, Turkey.
author
Özlem Celebi
Erdivanli
Department of Otorhinolaryngology, Recep Tayyip Erdogan University of Medical Faculty, Rize, Turkey.
author
Başar
Erdivanlı
Department of Anaesthesiology and Reanimation, Recep Tayyip Erdogan University of Medical Faculty, Rize, Turkey.
author
İbrahim
Şehitoğlu
Department of Pathology, Recep Tayyip Erdogan University of Medical Faculty, Rize, Turkey.
author
Engin
Dursun
Department of Otorhinolaryngology, Recep Tayyip Erdogan University of Medical Faculty, Rize, Turkey.
author
text
article
2015
eng
Introduction:
Choristoma is defined as the presence of cells in abnormal locations due to defects during embryological development. The word choristoma implies a neoplasm; whereas heterotopia refers to a displaced tissue without necessarily being a swelling or a neoplasm. Literature contains reports of cartilaginous choristoma in the cervix, endometrium, breast tissue, and oral region.
Case Reports:
Three cases of cartilaginous choristoma, which were accidentally found during microscopic examination of excised tonsil tissues, are presented.
Conclusion:
Choristomas may cause difficulty in the differential diagnosis of true neoplasms, since they are rare and may grow. Therefore pathologists should be considered in the differential diagnosis of cartilaginous lesions, because cartilaginous choristomas of the tonsil are a rare entity.
Iranian Journal of Otorhinolaryngology
Mashhad University of Medical Sciences (MUMS)
2251-7251
27
v.
4
no.
2015
325
328
https://ijorl.mums.ac.ir/article_4243_df4099afdf5e3030936ec04fc268b4fd.pdf
dx.doi.org/10.22038/ijorl.2015.4243