ORIGINAL_ARTICLE
Effects of Gabapentin Suspension and Rectal Acetaminophen on Postoperative Pain of Adenotonsillectomy in Children
Introduction:Adenotonsillectomy is the main treatment for symptomatic tonsillar hypertrophy with postoperative pain as the most common associated complication. The present study aimed to compare the efficacy of gabapentin with that reported for acetaminophen on the postoperative pain of adenotonsillectomy in children. Materials and Methods:In this double-blind clinical trial, a total of 60 children within the age range of 7-15 years undergoing adenotonsillectomy were randomly allocated to two groups of gabapentin (n=30) and acetaminophen (n=30). The first group received a 10 mg/kg dose of gabapentin suspension preoperatively and placebo (suppository) after the intubation. The second group received a 40 mg/kg dose of acetaminophen suppository and placebo suspension simultaneous with that in the case group. Using the pain scale (based on the scoreof visual analog scale, prescribed drugs, dosage as well as incidence of postoperative nausea and vomiting were recorded 0, 2, 4, 6, 12, and 24 h after the surgery. The data were analyzed using SPSS software (version 22.0). A p-value less than 0.05 was considered statistically significant. Results:There was no significant difference between the two groups considering the pain scores at 0, 2, 4, 6, 12, and 24 h after the surgery. In addition, the trend of pain intensity statistically decreased within 0 to 24 h in both acetaminophen (P<0.001) and gabapentin (P<0.001) groups. No statistically significant difference was observed between the two groups regarding the postoperative incidence of nausea and vomiting. Conclusion:The obtained results of the present study showed that the administration of gabapentin and acetaminophen significantly reduced the postoperative pain of tonsillectomy and need for narcotics in these patients after the surgery. However, in this study, there was no particular reported superiority for any of the two groups in terms of the effects of gabapentin suspension and rectal acetaminophen.
https://ijorl.mums.ac.ir/article_16027_5b6e20e287f768b9985053831fc6dcdf.pdf
2020-07-01
197
205
10.22038/ijorl.2020.38811.2283
Acetaminophen
Adenoidectomy
Gabapentin
Pain
Tonsillectomy
Soudabeh
Haddadi
so_haddadi@yahoo.com
1
Anesthesia Research Center, Department of Anesthesiology, Alzahra Hospital,Guilan University of Medical Sciences, Rasht, Iran.
LEAD_AUTHOR
Shideh
Marzban
shideh42@yahoo.com
2
Anesthesia Research Center, Department of Anesthesiology, Alzahra Hospital,Guilan University of Medical Sciences, Rasht, Iran.
AUTHOR
Arman
Parvizi
arman_parvizi@yahoo.com
3
Anesthesia Research Center, Department of Anesthesiology, Alzahra Hospital,Guilan University of Medical Sciences, Rasht, Iran.
AUTHOR
Shadman
Nemati
drshadmannemati@yahoo.com
4
Rhino-Sinus, Ear, and Skull Base Diseases Research Center, Department of Otolaryngology and Head and Neck Surgery, Amiralmomenin Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
AUTHOR
Aamer
Chohdari
aamerchohdary@yahoo.com
5
Anesthesiologist, Guilan University of Medical Sciences, Rasht, Iran.
AUTHOR
Zahra
Atrkar Roshan
atrkarroushan@gmail.com
6
Anesthesia Research Center, Department of Anesthesiology, Alzahra Hospital,Guilan University of Medical Sciences, Rasht, Iran.
AUTHOR
Hedieh
Ramezani
hediehr1392@gmail.com
7
Rhino-Sinus, Ear, and Skull Base Diseases Research Center, Department of Otolaryngology and Head and Neck Surgery, Amiralmomenin Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
AUTHOR
Asadi HK, Nikooseresht M, Noori L, Behnoud F. The effect of administration of ketamine and paracetamol versus paracetamol singly on postoperative pain, nausea and vomiting after pediatric adenotonsillectomy. Anesthesiology and Pain Medicine. 2016;6(1):8.
1
Moiniche S, Romsing J, Dahl JB, Tramer MR. Nonsteroidal antiinflammatory drugs and the risk of operative site bleeding after tonsillectomy: a quantitative systematic review. Anesth Analg. 2003; 96(1):68-77.
2
Sowder JC, Gale CM, Henrichsen JL, Veale K, Liljestrand KB, Ostlund BC, et al. Primary caregiver perception of pain control following pediatric adenotonsillectomy: a cross-sectional survey. Otolaryngology–Head and Neck Surgery. 2016;155(5):869-75.
3
Curtis JL, Harvey DB, Willie S,Narasimhan E,Andrews S, Henrichsen J, et al. Causes and costs for ED visits after pediatric adenotonsillectomy. Otolaryngol Head Neck Surg. 2015; 152:691-6.
4
Watcha MF, White PF. Postoperative nausea andvomiting: Its etiology treatment and prevention. JAnesthesiology. 1992; 77: 162-84.
5
Rahimzadeh P, Safari S, Imani F. Pediatric Chronic Pain Management: Steps Toward a Neglected J Comprehens Pediatr.2012;4(1):47-8.
6
Becke K, Albrecht S, Schmitz B, Rech D, Koppert W, Schuttler J, et al. Intraoperative low-dose S-ketamine has no preventive effects on postoperative pain and morphine consumption after major urological surgery in children. Paediatr Anaesth. 2005;15(6):484–90.
7
Yeganeh MA, Fazel MR, Parviz Sh. Comparison of Analgesic Effect Between Gabapentin and Diclofenac on Post-Operative Pain in Patients Undergoing Tonsillectomy. Arch Trauma Res. 2012 ; 1(3): 108–11.
8
Alebouyeh MR, Imani F, Golsokhan H, Entezari SR, Sayarifard A. topical analgesic effect of tramadol on postoperative pain control after tonsillectomy or adenotonsillectomy in children. JAP. 2014;4(3):21-9.
9
Hwang SH, Park IJ, Cho YJ, Jeong YM, Kang JM. The efficacy of gabapentin/pregabalin in improving pain after tonsillectomy: A meta‐analysis. The Laryngoscope. 2016;126(2):357-66.
10
Manica D, Sekine L, Abreu LS, Manzini M, Rabaioli L, Valério MM, et al. Influence of dietary and physical activity restriction on pediatric adenotonsillectomy postoperative care in Brazil: a randomized clinical trial. Brazilian journal of otorhinolaryngology. 2018;84(2):191-5.
11
Amani S, Abedinzadeh MR. Effects of oral gabapentin, local bupivacaine and intravenous pethidine on post tonsillectomy pain. Iranian journal of otorhinolaryngology. 2015;27(82):343.
12
Mikkelsen S, Hilsted KL, Andersen PJ, Hjortsø NC, Enggaard TP, Jørgensen DG, et al.The effect of gabapentin on post-operative pain following tonsillectomy in adults. Acta Anaesthesiol Scand. 2006;50(7):809-15.
13
Jeon EJ, Park YS, Park SS, Lee SK, Kim DH. The effectiveness of gabapentin on post-tonsillectomy pain control. Eur Arch Otorhinolaryngol. 2009;266(10):1605-9.
14
Clarke H, Bonin RP, Orser BA, Englesakis M, Wijeysundera DN, Katz J. The prevention of chronic postsurgical pain using gabapentin and pregabalin: a combined systematic review and meta-analysis. Anesth Analg. 2012;115(2):428-42.
15
Moore A. Gabapentin and Post Tonsillectomy Pain-The Next Best Thing? Arch Trauma Res. 2013;1(4): 188-90.
16
Ozcan S, Yilmaz E, Buyukkocak U, Basar H, ApanA. Comparison of three analgesic for extracorporealshockwave lithotripsy. Scand. J. Urol. Nephrol .2002;36(4):281-285.
17
Haddadi S, Marzban S, Karami M S, Heidarzadeh A, Parvizi A, Nabi BN. Comparing the duration of the analgesic effects of intravenous and rectal acetaminophen following tonsillectomy in children. Anesth Pain Med. 2014;4(1):13.
18
Preoperative gabapentin for post tonsillectomy pain in children.http://clinical trials. gov: NCT01707420.
19
ORIGINAL_ARTICLE
Peritonsillar Ropivacaine Infiltration in Paediatric Tonsillectomy: A Randomised Control Trial
Introduction:Various efforts have been made to reduce post tonsillectomy pain in children. The present study was undertaken to evaluate the efficacy and safety of Ropivacaine in post-operative pain management in these children.Materials and Methods:This study is a Randomized control study on 140 patients between 4 - 12 years of age, in whom tonsillectomy was performed in a tertiary care centre between January 2017 to November 2018 using standard dissection and snare surgical technique. Postoperatively, patients were randomized into 2 groups of 70 patients each, receiving tonsillar fossa infiltration with 0.2% Ropivacaine or 0.9% normal saline respectively. Patients were assessed as per Wong Baker’s Faces Scoring System at 2 hours, 4 hours, 8 hours, 18 hours, 24 hours, and 48 hours postoperatively. All the results were analyzed by SPSS software. Chi- square test and Mann-Whitney test were used for assessment of level of significance, with P- value of less than 0.05 taken as significant. Results:Both the groups were comparable with respect to age and sex. At 48 hours, in study group, maximum number of patients 35 (50%) had Wong Baker score 0, while in control group, maximum number of patients 52 (74.3%) had Wong Baker score 4 (P< 0.01). The difference in the mean Deglutition time between both groups was significant (P< 0.01).Conclusion:Ropivacaine infiltration is a effective modality for post-tonsillectomy pain management in children, with minimal side-effects.
https://ijorl.mums.ac.ir/article_16025_6114ec6359a81c77a1c62b277a912892.pdf
2020-07-01
207
212
10.22038/ijorl.2020.36577.2199
Post operative analgesia
Ropivacaine
Tonsillectomy
Arvinder-Singh
Sood
arvindersinghsood@gmail.com
1
Department of Otorhinolaryngology, SGRD Institute of Medical Sciences and Research, Amritsar, Punjab, India – 143001.
AUTHOR
Pooja
Pal
drpoojapal@gmail.com
2
Department of Otorhinolaryngology, SGRD Institute of Medical Sciences and Research, Amritsar, Punjab, India – 143001.
LEAD_AUTHOR
Gurupreet-Singh
Gill
gurugill2007@gmail.com
3
Department of Otorhinolaryngology, SGRD Institute of Medical Sciences and Research, Amritsar, Punjab, India – 143001.
AUTHOR
Perry ME. The specialized structure of crypt epithelium in the human palatine tonsil and its functional significance. J Anat 1994;185(Pt1):
1
Park AH, Pappas AL, Fluder E, Creech S, Lugo RA, Hotaling A. Effect of perioperative administration of ropivacaine with epinephrine on postoperative pediatric adenotonsillectomy recovery. Arch Otolaryngol Head Neck Sur 2004;130(4):459-64.
2
Farmawy MS, Rashad MM. Preemptive analgesia by peritonsillar ketamine versus ropivacaine for post-tonsillectomy pain in children. Egyptian Journal of Anaesthesia 2014; 30(1): 1- 5.
3
Aremu SK. A Review of Tonsillectomy Techniques and Technologies. INTECH Open Access Publisher; 2012:162.
4
Zadeh FJ, Derakhshandeh B, Atigh F. The role of local injection of Bupivacaine in the management of pain after tonsillectomy surgery. International Journal of Bioassays 2016;5(01): 4697-700.
5
Wall PD. The prevention of postoperative pain. Pain 1988;33(3):289-90.
6
Cook AJ, Woolf CJ, Wall PD, McMahon SB. Expansion of cutaneous receptive fields of dorsal horn neurones following C-primary afferent fibre inputs. Nature 1987;325:151-3.
7
Woolf CJ. Evidence for a central component of post-injury pain hypersensitivity. Nature 1983;306(5944):686-8.
8
Coulthard P, Haywood D, Tai MA, Jackson-Leech D, Pleuvry BJ, Macfarlane TV. Treatment of postoperative pain in oral and maxillofacial surgery. Brit J Oral Max Surg 2000;38(6):588-92.
9
Ju NY, Cui GX, Gao W. Ropivacaine plus dexamethasone infiltration reduces postoperative pain after tonsillectomy and adenoidectomy. Int J Pediatr Otorhinolaryngol 2013;77(11):1881–5.
10
Goutham MK, Ravishankara S, Naik SM, Sathya P, Appaji M, Bhat S. Comparison of local infiltration of ropivacaine, bupivacaine, topical application of sucralfate in the tonsillar fossa on post-tonsillectomy pain. Otolaryngol Online J 2014; 4:105-116.
11
ORIGINAL_ARTICLE
Cultural Adaptation of Sniffin’ Sticks Smell Identification Test: The Malaysian Version
Introduction:Sniffin’ Sticks smell identification test is a tool used for evaluation of olfactory function but the results are culture-dependent. It relies on the subject’s familiarity to the odorant and descriptors. This study aims to develop the Malaysian version of Sniffin’ Sticks smell identification test suitable for local population usage.Materials and Methods: The odorant descriptors and distractors of the original version of Sniffin’ Sticks were translated into Malay language. It was then tested for familiarity and identifiability in 30 normosmic subjects. The descriptors were replaced until the familiarity of all descriptors and identification rates of odorants achieved ≥ 70%. The validity of the new cultural-adapted version was tested in 60 hypo-anosmic subjects and 60 normosmic subjects with Student t-test. The test-retest reliability was evaluated after two weeks with interclass correlation.Results:Two odorant descriptors and nine distractors achieved familiarity <70% (13.3% - 66.7%) and were replaced. Another three culturally inappropriate distractors were also replaced. The mean score among the healthy subjects was significantly higher than the subject with smell dysfunction [13.7 (1.12) and 7.3 (3.42); t= 7.24 (df= 34.23), P<0.001]. The coefficient of correlation (r) between test and retest scores was 0.93 (P<0.001).Conclusion:The cultural adapted Malaysian version of Sniffin’ Sticks smell identification test is valid and has high test-retest reliability. This is the first smell identification test validated in Malaysia. It is effective for evaluation of olfactory function in local population.
https://ijorl.mums.ac.ir/article_16024_7493db8c3d9dc79a4b45901a046c8cee.pdf
2020-07-01
213
222
10.22038/ijorl.2019.34346.2138
cultural adaptation
Olfaction
Smell
Smell Identification
Sniffin’ Sticks
Lum
Sai-Guan
lumsg728@gmail.com
1
Department of Otorhinolaryngology – Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
LEAD_AUTHOR
Salina
Husain
drsalina_h@yahoo.com
2
Department of Otorhinolaryngology – Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
AUTHOR
Farah-Dayana
Zahedi
anna_firra82@yahoo.com.au
3
Department of Otorhinolaryngology – Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
AUTHOR
Norfazilah
Ahmad
norfazilah@ppukm.ukm.edu.my
4
Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
AUTHOR
Balwant-Singh
Gendeh
bsgendeh@gmail.com
5
Department of Otorhinolaryngology – Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
AUTHOR
Stevenson RJ. An initial evaluation of the functions of human olfaction. Chem Senses 2010; 35: 3–20.
1
Landis BN, Hummel T, Lacroix JS. Basic and Clinical Aspects of Olfaction. Advances and Technical Standards in Neurosurgery 2005;30:75-7.
2
Thomas-Danguin T, Rouby C, Sicard G, Vigouroux M, Johansson A, Bengtzon A, et al. Odour identification and discrimination: influence of culture and typicality on performance. Chem Senses 2001; 26: 1062.
3
Kobal G, Hummel T, Sekinger B, Barz S, Roscher S, Wolf S. Sniffin' Sticks: screening of olfactory performance. Rhinology 1996; 34: 222-6.
4
Hummel T, Sekinger B, Wolf SR, Pauli E, Kobal G. 'Sniffin' Sticks': olfactory performance assessed by the combined testing of odor identification, odor discrimination and olfactory threshold. Chem Senses 1997; 22: 39-52.
5
Kobal G, Klimek L, Wolfensberger M, Gudziol H, Temmel A, Owen CM, et al. Multicenter investigation of 1,036 subjects using a standardized method for the assessment of olfactory function combining tests of odor identification, odor discrimination, and olfactory thresholds. Eur Arch Otorhinolaryngol 2000; 257: 205-11.
6
Hummel T, Kobal G, Gudziol H, Mackay-Sim A. Normative data for the “Sniffin' Sticks” including tests of odor identification, odor discrimination, and olfactory thresholds: an upgrade based on a group of more than 3,000 subjects. Eur Arch Otorhinolaryngol 2007; 264: 237-43.
7
Katotomichelakis M, Balatsouras D, Tripsianis G, Tsaroucha A, Homsioglou E, Danielides V. Normative values of olfactory function testing using the ‘Sniffin’Sticks'. The Laryngoscope 2007; 117(1): 114-20.
8
Mackay-Sim A, Grant L, Owen C, Chant D, Silbur P. Australian norms for a quantitative olfactory function test. J Clin Neurosci 2004; 11(8): 874-9.
9
Konstantinidis I, Printza A, Genetzaki S, Mamali K, Kekeş G, Constantinidis J. Cultural adaptation of an olfactory test: The Greek version of Sniffin' Sticks. Rhinology 2008; 46: 292-6.
10
Boesveldt S, Verbaan D, Knol DL, Van Hilten JJ, Berendse HW. Odour identification and discrimination in Dutch adults over 45 years. Rhinology 2008; 46(2): 131.
11
Eibenstein A, Fioretti AB, Lena C, Rosati N, Ottoviano I, Fusetti M. Olfactory screening test: experience in 102 Italian subjects. Acta Otorhinolaryngol Ital 2005; 25: 18-22.
12
Ribeiro JC, Simões J, Silva F, Silva ED, Hummel C, Hummel T. Cultural Adaptation of the Portuguese Version of the “Sniffin’Sticks” Smell Test: Reliability, Validity, and Normative Data. PloS one 2016; 11(2): e0148937.
13
Neumann C, Tsioulos K, Merkonidis C, Salam M, Clark A, Philpott C. Validation study of the “Sniffin' Sticks” olfactory test in a British population: a preliminary communication. Clinical Otolaryngology 2012; 37(1): 23-7.
14
Catana IV, Negoias SI, Maniu AL, Cosgarea MA. The assessment of sense of smell in a Romanian northern population: normative values using" sniffins sticks" olfaction test. Clujul Medical 2013; 86: S56-9.
15
Oleszkiewicz A, Taut M, Sorokowska A, Radwan A, Kamel R, Hummel T. Development of the Arabic version of the “Sniffin’Sticks” odor identification test. Eur Arch Otorhinolaryngol 2016; 273(5): 1179-84.
16
Oniz A, Erdogan I, Ikiz AO, Evirgen N, Ozgoren M. The modified Sniffin’sticks test in Turkish population based on odor familiarity survey. J Neurol Sci Turk 2013; 30: 270-80.
17
Yuan BC, Lee PL, Lee YL, Lin SH, Shu CH. Investigation of the Sniffin' Sticks olfactory test in Taiwan and comparison with different continents. J Med Assoc 2010; 73(9): 483-6.
18
Shu CH, Yuan BC. Assessment of odor identification function in Asia using a modified “Sniffin' Stick” odor identification test. Eur Arch Otorhinolaryngol 2008; 265: 787-90.
19
Shu CH, Yuan BC, Lin SH, Lin CZ. Cross-cultural application of the "Sniffin' Sticks" odor identification test. Am J Rhinol 2007; 21(5): 570-3.
20
Silveira-Moriyama L., Sirisena D., Gamage P, Gamage R, de Silva R, Lees AJ. Adapting the Sniffin’ Sticks to diagnose Parkinson’s disease in Sri Lanka. Mov Disord 2009;24:1229–33.
21
Cho JH, Jeong YS, Lee YJ, Hong SC, Yoon JH, Kim JK. The Korean version of the Sniffin’stick (KVSS) test and its validity in comparison with the cross-cultural smell identification test (CC-SIT). Auris Nasus Larynx 2009; 36(3): 280-6.
22
Silveira‐Moriyama L, Carvalho MD, Katzenschlager R, Petrie A, Ranvaud R, Barbosa ER, et al. The use of smell identification tests in the diagnosis of Parkinson's disease in Brazil. Mov Disord 2008; 23(16): 2328-34.
23
Haehner A, Mayer AM, Landis BN, Pournaras I, Lill K, Gudziol V, et al. High test–retest reliability of the extended version of the “Sniffin’Sticks” test. Chem senses 2009; 34(8):
24
Ho WK, Kwong DL, Wei WI, Sham JS. Change in olfaction after radiotherapy for nasopharyngeal cancer-a prospective study. Am J Otolaryngol 2002; 23(4): 209-14.
25
Gudziol V, Hummel T. The influence of distractors on odor identification. Arch Otolaryngol Head Neck Surg 2009; 135(2): 143-5.
26
Antsov E, Silveira-Moriyama L, Kilk S, Kadastik-Eerme L, Toomsoo T, Lees A, et al. Adapting the Sniffin'Sticks olfactory test to diagnose Parkinson's disease in Estonia. Parkinsonism Relat Disord 2014; 20(8): 830-3.
27
Doty RL, Shaman P, Dann M. Development of the University of Pennsylvania Smell Identification Test: a standardized microencapsulated test of olfactory function.Physiol Behav 1984;32(3):489-502.
28
ORIGINAL_ARTICLE
Assessment of Surgeon Judgment during Resection of Laryngeal Carcinoma
Carbon dioxide (CO2) laser surgery as a conservative tool plays a peculiar role in the management of head and neck cancer. Numerous patients who were candidates for transoral laryngeal microsurgery have forced us to eliminate frozen-section evaluation of surgical margins and use a magnified view of the larynx. The present study evaluated surgeon-judged negative margins with permanent microscopic pathologic evaluation. Materials and Methods:In this cross-sectional study, we evaluated the permanent pathologic margins of the resected laryngeal specimen which were considered negative by judgment of surgeons. Patients consisted of 61 pathologic proven T1-T2 laryngeal squamous cell carcinoma (SCC) cases. In all patients, tumor resection was performed via a transoral route with CO2 laser, and no residual laryngeal tumor was observed according to judgment of the surgeon. The patients with positive margin (s) underwent another resection. Patients were followed up for 18 months for tumor recurrence. Results:The obtained results demonstrated that pathologic margins were reported in 6 patients, with the deep margin being the most common positive margin. During the 18-month follow-up, 8 cases of recurrence were detected. Conclusion:Judgment of the surgeon was in agreement with permanent pathologic evaluation in transoral laryngeal laser resection at the early stages of laryngeal SCC in most cases. Nevertheless, it is suggested that further direct studies be conducted to evaluate the frozen section on oncologic outcomes in transoral laser surgery for laryngeal cancer.
https://ijorl.mums.ac.ir/article_16026_98c0b3a1914089a96b3c71b6c3a23597.pdf
2020-07-01
223
227
10.22038/ijorl.2019.38025.2248
Laryngeal Squamous Cell Carcinoma
Laser microsurgery
Pathological study
Ebrahim
Karimi
karimient@gmail.com
1
Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Reza
Erfanian
r-erfanin@sina.tums.ir
2
Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Payman
Dabirmoghaddam
dabirmoghadam@sina.tums.ac.ir
3
Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Saeed
Shakiba
saed.shakiba@gmail.com
4
School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Saeed
Sohrabpour
dr.saeed.sohrabpour@gmail.com
5
Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
LEAD_AUTHOR
Mafi N, Kadivar M, Hosseini N, Ahmadi S, Zare-Mirzaie A. Head and neck squamous cell carcinoma in Iranian patients and risk factors in young adults: a fifteen-year study. Asian Pacific Journal of Cancer Prevention. 2012;13(7):3373-8.
1
Flint PW, Haughey BH, Niparko JK, Richardson MA, Lund VJ, Robbins KT, et al. Cummings Otolaryngology-Head and Neck Surgery E-Book: Head and Neck Surgery, 3-Volume Set: Elsevier Health Sciences; 2010.
2
Chiesa-Estomba CM, González-García JA, Larruscain E, Calvo-Henríquez C, Mayo-Yáñez M, Sistiaga-Suarez JA. CO2 Transoral Laser Microsurgery in Benign, Premalignant and Malignant (Tis, T1, T2) Lesion of the Glottis. A Literature Review. Medicines. 2019;6(3):77.
3
Batra A, Goyal A, Goyal M, Goel S. Oncological Outcomes Following Transoral CO 2 Laser Microsurgery for T1 Glottic Cancer. Indian Journal of Otolaryngology and Head & Neck Surgery. 2018;1-6.
4
Ambrosch P, Gonzalez-Donate M, Fazel A, Schmalz C, Hedderich J. Transoral laser Microsurgery for supraglottic cancer. Frontiers in oncology. 2018;8.
5
Coskun H, Mendenhall WM, Rinaldo A, Rodrigo JP, Suárez C, Strojan P, et al. Prognosis of subglottic carcinoma: Is it really worse? Head & neck. 2019;41(2):511-21.
6
Tjoa T, Armstrong WB. Transoral Laser Microsurgery for Laryngeal Cancer. Biomedical Optics in Otorhinolaryngology: Springer; 2016; p. 51-66.
7
Fang TJ, Courey MS, Liao CT, Yen TC, Li HY. Frozen margin analysis as a prognosis predictor in early glottic cancer by laser cordectomy. The Laryngoscope. 2013;123(6):1490-5.
8
Wong R, De Zoysa N, Fu B, Maskell S, Harries M. The significance of clinical margins in CO 2 laser resected laryngeal squamous cell carcinoma and its impact on disease management: Our experience in twenty‐nine patients. Clinical Otolaryngology. 2013;38(6):545-9.
9
Hendriksma M, Montagne MW, Langeveld TPM, Veselic M, van Benthem PPG, Sjögren EV. Evaluation of surgical margin status in patients with early glottic cancer (Tis-T2) treated with transoral CO(2) laser microsurgery, on local control. Eur Arch Otorhinolaryngol. 2018;275(9):2333-40.
10
Blanch JL, Vilaseca I, Bernal-Sprekelsen M, Grau J, Moragas M, Traserra-Coderch J, et al. Prognostic significance of surgical margins in transoral CO2 laser microsurgery for T1–T4 pharyngo-laryngeal cancers. European archives of oto-rhino-laryngology. 2007;264(9):1045-51.
11
Piazza C, Paderno A, Grazioli P, Del Bon F, Montalto N, Perotti P, et al. Laryngeal exposure and margin status in glottic cancer treated by transoral laser microsurgery. The Laryngoscope. 2018;128(5):1146-51.
12
ORIGINAL_ARTICLE
Effect of Vowel Auditory Training on the Speech-In-Noise Perception among Older Adults with Normal Hearing
Introduction:Aging reduces the ability to understand speech in noise. Hearing rehabilitation is one of the ways to help older people communicate effectively. This study aimed to investigate the effect of vowel auditory training on the improvement of speech-in-noise (SIN) perception among elderly listeners. Materials and Methods:This study was conducted on 36 elderly listeners (17 males and 15 females) with the mean±SD of 67.6±6.33. They had the normal peripheral auditory ability but had difficulties in SIN perception. The samples were randomly divided into two groups of intervention and control. The intervention group underwent vowel auditory training; however, the control group received no training. Results:After vowel auditory training, the intervention group showed significant changes in the results of the SIN test at two signal-to-noise ratios of 0 and -10 and the Iranian version of the Speech, Spatial, and Qualities of Hearing Scale, compared to the control group (P<0.001). Regarding the Speech Auditory Brainstem Response test, the F0 magnitude was higher in the intervention group (8.42±2.26), compared to the control group (6.68±1.87) (P<0.011). Conclusion:This study investigated the effect of vowel auditory training on the improvement of SIN perception which could be probably due to better F0 encoding and receiving. This ability enhancement resulted in the easier perception of speech and its more proper separation from background noise which in turn enhanced the ability of the old people to follow the speech of a specific person and track the discussion.
https://ijorl.mums.ac.ir/article_16022_ca70cf1fb21069de8ee0995a2721a808.pdf
2020-07-01
229
236
10.22038/ijorl.2019.33433.2110
Aging
Fundamental Frequency (F0)
Speech-in-Noise Perception
Vowel Auditory Training
Atta
Heidari
atta.heidari@gmail.com
1
Department of Audiology, Faculty of Rehabilitation, Hamadan University of Medical Sciences, Hamadan, Iran.
LEAD_AUTHOR
Abdollah
Moossavi
amoossavi@gmail.com
2
Department of Otolaryngology and Head and Neck Surgery, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
AUTHOR
Fariba
Yadegari
faribayadegari@yahoo.com
3
Department of Speech Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
AUTHOR
Enayatollah
Bakhshi
bakhshi@razi.tums.ac.ir
4
Department of Biostatistics, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
AUTHOR
Mohsen
Ahadi
mohsenahadi@gmail.com
5
Department of Audiology, Rehabilitation Research Center, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.
AUTHOR
Divenyi P. Speech separation by humans and machines: Springer Science & Business Media; 2004.
1
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Bregman AS. Auditory scene analysis: The perceptual organization of sound: MIT press; 1994.
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Winkler I, Kushnerenko E, Horváth J, Čeponienė R, Fellman V, Huotilainen M, et al. Newborn infants can organize the auditory world. Proceedings of the National Academy of Sciences. 2003;100(20):11812-5.
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Anderson S, Parbery-Clark A, Yi H-G, Kraus N. A neural basis of speech-in-noise perception in older adults. Ear and hearing. 2011; 32(6):750.
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Krishnan A, Xu Y, Gandour J, Cariani P. Encoding of pitch in the human brainstem is sensitive to language experience. Cognitive Brain Research. 2005;25(1):161-8.
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Anderson S, Skoe E, Chandrasekaran B, Zecker S, Kraus N. Brainstem correlates of speech-in-noise perception in children. Hearing research. 2010;270(1):151-7.
15
Gaudrain E, Grimault N, Healy EW, Béra J-C. Streaming of vowel sequences based on fundamental frequency in a cochlear-implant simulation a. The Journal of the Acoustical Society of America. 2008;124(5):3076-87.
16
Oxenham AJ. Pitch perception and auditory stream segregation: implications for hearing loss and cochlear implants. Trends in amplification. 2008;12(4):316-31.
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Vander Werff KR, Burns KS. Brain stem responses to speech in younger and older adults. Ear and hearing. 2011;32(2):168-80.
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Bidelman GM, Villafuerte JW, Moreno S, Alain C. Age-related changes in the subcortical–cortical encoding and categorical perception of speech. Neurobiology of aging.2014;35(11):
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Peters RW, Moore BC. Auditory filter shapes at low center frequencies in young and elderly hearing‐impaired subjects. The Journal of the Acoustical Society of America.1992;91(1):
20
Heidari A, Moossavi A, Yadegari F, Bakhshi E, Ahadi M. Effects of Age on Speech-in-Noise Identification: Subjective Ratings of Hearing Difficulties and Encoding of Fundamental Frequency in Older Adults. Korean Journal of Audiology. 2018.
21
Alain C, Zendel BR, Hutka S, Bidelman GM. Turning down the noise: the benefit of musical training on the aging auditory brain. Hearing research. 2014;308:162-73.
22
Russo NM, Nicol TG, Zecker SG, Hayes EA, Kraus N. Auditory training improves neural timing in the human brainstem. Behavioural brain research. 2005;156(1):95-103.
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Strait DL, Slater J, O’Connell S, Kraus N. Music training relates to the development of neural mechanisms of selective auditory attention. Developmental cognitive neuroscience. 2015;12:
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Swaminathan J, Mason CR, Streeter TM, Best V, Kidd Jr G, Patel AD. Musical training, individual differences and the cocktail party problem. Scientific reports. 2015;5.
25
Tierney AT, Krizman J, Kraus N. Music training alters the course of adolescent auditory development. Proceedings of the National Academy of Sciences. 2015;112(32):10062-7.
26
Delphi M, Lotfi Y, Moossavi A, Bakhshi E, Banimostafa M. Envelope-based inter-aural time difference localization training to improve speech-in-noise perception in the elderly. Medical journal of the Islamic Republic of Iran. 2017;31:36.
27
Nazeri A-R, Lotfi Y, Moosavi A, Zamiri F, Delfi M. Auditory processing disorders in elderly people. Rehabilitation Medicine. 2014;3(1).
28
Mosleh M. Development and evaluation of a speech recognition test for Persian speaking adults. Bimonthly Audiology-Tehran University of Medical Sciences. 2001;9(1):72-6.
29
Omidvar S, Jafari Z, Tahaei AA, Salehi M. Comparison of auditory temporal resolution between monolingual Persian and bilingual Turkish-Persian individuals. International journal of audiology. 2013;52(4):236-41.
30
Lotfi Y, Nazeri AR, Asgari A, Moosavi A, Bakhshi E. Iranian Version of Speech, Spatial, and Qualities of Hearing Scale: A Psychometric Study. Acta Medica Iranica. 2017;54(12):756-64.
31
Humes LE, Kinney DL, Brown SE, Kiener AL, Quigley TM. The effects of dosage and duration of auditory training for older adults with hearing impairment. The Journal of the Acoustical Society of America. 2014;136(3):EL224-EL30.
32
Jafari Z, Omidvar S, Jafarlou F, Kamali M. The Effect Of Age On Speech Temporal Resolution Among Elderly People. 2011.
33
Stuart A, Phillips DP. Word recognition in continuous and interrupted broadband noise by young normal-hearing, older normal-hearing, and presbyacusic listeners. Ear and hearing. 1996; 17(6):478-89.
34
Singh G, Kathleen Pichora-Fuller M. Older adults’ performance on the speech, spatial, and qualities of hearing scale (SSQ): Test-retest reliability and a comparison of interview and self-administration methods. International journal of audiology. 2010;49(10):733-40.
35
Vongpaisal T, Pichora-Fuller MK. Effect of age on F0 difference limen and concurrent vowel identification. Journal of Speech, Language, and Hearing Research. 2007;50(5):1139-56.
36
Ahadi M, Pourbakht A, Jafari AH, Jalaie S. Effects of stimulus presentation mode and subcortical laterality in speech-evoked auditory brainstem responses. International journal of audiology. 2014;53(4):243-9.
37
Edwards CJ, Leary CJ, Rose GJ. Mechanisms of long-interval selectivity in midbrain auditory neurons: roles of excitation, inhibition, and plasticity. Journal of neurophysiology. 2008; 100(6): 3407-16.
38
Hall J. GABAergic inhibition shapes frequency tuning and modifies response properties in the auditory midbrain of the leopard frog. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology. 1999; 185(5):479-91.
39
Song JH, Skoe E, Wong PC, Kraus N. Plasticity in the adult human auditory brainstem following short-term linguistic training. Journal of cognitive neuroscience. 2008;20(10):1892-902.
40
Russo N, Nicol T, Musacchia G, Kraus N. Brainstem responses to speech syllables. Clinical Neurophysiology. 2004;115(9):2021-30.
41
Skoe E, Kraus N. Auditory brainstem response to complex sounds: a tutorial. Ear and hearing. 2010;31(3):302.
42
Anderson S, Skoe E, Chandrasekaran B, Kraus N. Neural timing is linked to speech perception in noise. Journal of Neuroscience. 2010;30(14):4922-6.
43
ORIGINAL_ARTICLE
Evaluation of the Quality of Otolaryngology Information on Persian Websites
Introduction:More and more patients are using the Internet to achieve information these days. Most patients (85%) use search engines to look for information about health. The quality of this information that patients encounter is highly different. This study aimed to assess the quality of information that an ear, nose, and throat patient would encounter when searching for information about their problem. Materials and Methods:The Persian keywords of most common otolaryngology problems were searched in Google. Moreover, the first 10 websites were selected by each search for the analysis using the DISCERN instrument. This instrument is made to evaluate the comprehensiveness and quality of health-related websites. Results:A total of 100 websites were evaluated in this study. However, 12 (12%) websites were excluded from further analysis due to copyright problems, advertisements, traditional treatments, and other reasons. The total DISCERN score for all 88 evaluated websites was obtained at 1.89 (SD=0.49). Moreover, the highest and lowest scores were 3.66 and 1.21, respectively. The search for “otitis treatment” had the highest results (mean DISCERN score=2.20, SD=0.38). The statistical analysis showed that the mean score for the Wikipedia.com Persian website was significantly higher, compared to the other Persian websites (P< 0.001). Conclusion:Persian websites have information with variable quality for the treatment of otolaryngology problems. Repeated websites, such as Wikipedia.com provided better information; however, the total quality of information was not satisfying.
https://ijorl.mums.ac.ir/article_16023_45562c7f2a2681800df7d2b54d911ee4.pdf
2020-07-01
237
241
10.22038/ijorl.2019.31379.2031
Google
health
internet
Quality
Ali
Kouhi
ali.kouhi@gmail.com
1
Otolaryngology Research Ccenter, Department of Otolaryngology, Head and Neck Surgery, Amir-Al’am Hospital, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Sasan
Dabiri
sasandabiri@gmail.com
2
Otolaryngology Research Ccenter, Department of Otolaryngology, Head and Neck Surgery, Amir-Al’am Hospital, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Alireza
Mohseni
alirm08@yahoo.com
3
Otolaryngology Research Ccenter, Department of Otolaryngology, Head and Neck Surgery, Amir-Al’am Hospital, Tehran University of Medical Sciences, Tehran, Iran.
LEAD_AUTHOR
Mohammadtaha
Kouchakinezhad Eramsadati
taha.kouchakinejad@gmail.com
4
Otolaryngology Research Ccenter, Department of Otolaryngology, Head and Neck Surgery, Amir-Al’am Hospital, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
McMullan M. Patients using the Internet to obtain health information: how this affects the patient-health professional relationship. Patient Educ Couns. 2006;63(1-2):24-8.
1
Rothschild MA. Otolaryngology and the Internet. E-mail and the World Wide Web. Otolaryngol Clin North Am. 1998;31(2):255-76.
2
Samadbeik M, Ahmadi M, Mohammadi A, Mohseni Saravi B. Health Information on Internet: Quality, Importance, and Popularity of Persian Health Websites. Iranian Red Crescent Medical Journal. 2014;16(4).
3
Jadad AR, Gagliardi A. Rating health information on the Internet: navigating to knowledge or to Babel? JAMA. 1998;279(8):611-4.
4
Ybarra ML, Suman M. Help seeking behavior and the Internet: a national survey. Int J Med Inform. 2006;75(1):29-41.
5
Eysenbach G, Powell J, Kuss O, Sa ER. Empirical studies assessing the quality of health information for consumers on the world wide web: a systematic review. JAMA. 2002;287(20): 2691-700.
6
Barker S, Charlton NP, Holstege CP. Accuracy of internet recommendations for prehospital care of venomous snake bites. Wilderness Environ Med. 2010;21(4):298-302.
7
Internet World Stats. Top 20 countries with the highest number of internet users 2017, Dec 31, [Cited 2018, Apr 2]. Available from: http://www. internetworldstas.com/stats5.htm.
8
Rezailashkajani M, Roshandel D, Ansari S, Zali MR. A web-based patient education system and self-help group in Persian language for inflammatory bowel disease patients. Int J Med Inform. 2008;77(2):122-8.
9
Chang MY, Han DH, Moon IJ, Kim ST, Kim DY, Lee CH, et al. Assessment of allergic rhinitis websites in Korea. Clin Exp Otorhinolaryngol. 2010;3(1):32-6.
10
Silva LVER, de Mello JF, Mion O. Evaluation of Brazilian web site information on allergic rhinitis. Braz J Otorhinolaryngol. 2005; 71(5):590-7.
11
Harland J, Bath P. Assessing the quality of websites providing information on multiple sclerosis: evaluating tools and comparing sites. Health informatics journal. 2007;13(3):207-21.
12
Banasiak NC, Meadows-Oliver M. Evaluating asthma websites using the Brief DISCERN instrument. J Asthma Allergy. 2017;10:191-6.
13
O'Connell Ferster AP, Hu A. Evaluating the quality and readability of Internet information sources regarding the treatment of swallowing disorders. Ear Nose Throat J. 2017;96(3):128-38.
14
Shahrzadi L, Mojiri S, Janatian S, Taheri B, Ashrafi-rizi H, Shahrzadi Z, et al. Quality Assessment of Persian Mental Disorders Websites Using the Webmedqual Scale. Acta Informatica Medica. 2014;22(3):183-8.
15
Zahedi R, Taheri B, Shahrzadi L, Tazhibi M, Ashrafi-rizi H. Quality of persian addiction websites: a survey based on silberg, discern and wqet instruments (2011). Acta Informatica Medica. 2013; 21(1):46-50.
16
Samadbeik M, Ahmadi M, Mohammadi A, Mohseni Saravi B. Health information on internet: quality, importance, and popularity of persian health websites. Iranian Red Crescent Medical Journal. 2014; 16(4):e12866.
17
Sullivan D. Google Still World’s Most Popular Search Engine By Far, But Share Of Unique Searchers Dips Slightly 2013, Feb 11, [cited: 2017, Mar 17]. Available from: https://searchengineland. com/ google-worlds-most-popular-search-engine-148089.
18
Diaz JA, Griffith RA, Ng JJ, Reinert SE, Friedmann PD, Moulton AW. Patients' use of the Internet for medical information. J Gen Intern Med. 2002; 17(3):180-5.
19
Fox S. Online health search 2006. Pew Internet and American Life Project 2006 Oct 29. [cited: 2017 Mar 17]. available from: http://www. pewinternet.org/~/media//Files/Reports/2006/PIP_Online_Health_2006.pdf.pdf. Accessed January 6, 2012.
20
ORIGINAL_ARTICLE
Schwannoma of the Brachial Plexus: A Rare Case Report
Introduction:Brachial plexus schwannomas are extremely rare tumours of the head and neck region accounting for less than 5 % overall. Due to its rarity and anatomic complexity of the brachial plexus, schwannomas in this region present a diagnostic and surgical challenge to the surgeon. Case Report:We present a case of a 56-year-old female who presented with a slow growing right sided neck swelling associated with pain and tingling in the distal end of the right forearm. According to FNAC, imaging studies results, a diagnosis of benign neurogenic tumour possibly schwannoma was made. After taking proper consent patient underwent surgical excision of the tumour. Postoperatively, patient developed numbness and tingling in right arm and stiffness at elbow joint, which is showing improvement after regular physiotherapy sessions. Conclusion:Although brachial plexus schwannomas, extremely rare head and neck tumours, should be kept as a differential diagnosis in patients presenting with supraclavicular neck swellings. These are potentially curable lesions. As such, detailed history and examination together with imaging studies is important is establishing a preoperative diagnosis for proper management.
https://ijorl.mums.ac.ir/article_16028_28368ddb55cb72a3488708e16d2e3ac5.pdf
2020-07-01
243
247
10.22038/ijorl.2020.40635.2330
Brachial Plexus
Neurofibroma
Schwannomas
Shruti
Ranjan
shrutiranjan24@gmail.com
1
Department of ENT & Head and Neck Surgery Dr. Baba Saheb Ambedkar Medical College and Hospital Rohini (West), Sector 6, New Delhi – 110085.
LEAD_AUTHOR
Nikhil
Arora
for_nikhilarora@yahoo.com
2
Department of ENT & Head and Neck Surgery Dr. Baba Saheb Ambedkar Medical College and Hospital Rohini (West), Sector 6, New Delhi – 110085.
AUTHOR
Deepika
Sethi
dset17111978@gmail.com
3
Department of ENT & Head and Neck Surgery Dr. Baba Saheb Ambedkar Medical College and Hospital Rohini (West), Sector 6, New Delhi – 110085.
AUTHOR
Daljeet
Kaur
drdaljeet@yahoo.com
4
Department of ENT & Head and Neck Surgery Dr. Baba Saheb Ambedkar Medical College and Hospital Rohini (West), Sector 6, New Delhi – 110085.
AUTHOR
Gyanesh
Sethi
gyan2s@gmail.com
5
Department of ENT & Head and Neck Surgery Dr. Baba Saheb Ambedkar Medical College and Hospital Rohini (West), Sector 6, New Delhi – 110085.
AUTHOR
Ansari I, Ansari A, Graison AA, Patil AJ, Joshi H. Head and Neck Schwannomas: A Surgical Challenge-A Series of 5 Cases. Case Reports in Otolaryngology. 2018 Mar 4; 2018:1–10.
1
Ryu KH, Moon JI, Baek HJ, Cho SB, Choi BH, An HJ et al. Brachial plexus schwannoma mimicking cervical lymphadenopathy: A case report with emphasis on imaging features. Medicine (Baltimore). 2018 Oct; 97(42).
2
Rashid M, Salahuddin O, Yousaf S, Qazi UA, Yousaf K. Schwannoma of the brachial plexus; report of two cases involving the C7 root. J Brachial Plex Peripher Nerve Inj.2013 Nov 4;8(1).
3
Kumar A, Akhtar S. Schwannoma of brachial plexus. Indian J Surg.2011 Jan;73(1):80-1.
4
Vishwanathan N, Suma Devi B. Unusual cervical mass - A surgical dilemma and unfortunate sequelae. Indian J Otolaryngol Head Neck Surg.2006 Jul; 58(3):275-6.
5
Lee HJ, Kim JH, Rhee SH, Gong HS, Baek GH. Is surgery for brachial plexus schwannomas safe and effective?. Clin Orthop Relat Res.2014 Jun; 472(6): 1893-8.
6
Yuce I, Kahyaoglu O, Mertan P, Cavusoglu H, Aydin Y. Ultrasound-Guided Microsurgical Excision for Brachial Plexus Schwannomas: Short-Term Clinical Study. Turk Neurosurg.2019 Feb 14.
7
Kohyama S, Hara Y, Nishiura Y, Hara T, Nakagawa T, Ochiai N. A giant plexiform schwannoma of the brachial plexus: case report. J Brachial Plex Peripher Nerve Inj.2011 Nov 1;06(01).
8
ORIGINAL_ARTICLE
Sensory-Neural Hearing Loss as an Early Rebound Relapse after Fingolimod Cessation in Multiple Sclerosis
Introduction:Multiple sclerosis (MS) is a lifelong disease of the brain and spinal cord. Fingolimod is an oral drug which modulates the S1P receptor and is used for relapsing remitting form of MS and can causes rebound activity if it is ceased even in a short period of washout time. Case Report:Here, we introduce a young girl, a known case of MS, who developed reversible isolated unilateral sensory-neural hearing loss along imaging activity two weeks after stopping fingolimod. The patient responded well to the intravenous corticosteroid therapy which is the first line treatment of new MS attack. Conclusion:fingolimod cessation can cause rebound activity in a short period of the time. It is important to consider any new neurological sign and symptom as a rebound activity during washout time. Although SNHL is not common in MS, it could be presented as an unusual manifestation of rebound relapse after stopping fingolimod.
https://ijorl.mums.ac.ir/article_16029_98f86f870b9ad723097b9de7dba5f9a7.pdf
2020-07-01
249
253
10.22038/ijorl.2020.40858.2334
Fingolimod
Multiple Sclerosis
Rebound activity
Abdoreza
Naser Moghadasi
abdorrezamoghadasi@gmail.com
1
Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Maryam
Poursadeghfard
poursadra@gmail.com
2
Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
LEAD_AUTHOR
Tayebeh
Kazemi
kazemi@sums.ac.ir
3
Otolaryngology Research Center, Department of Otolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran.
AUTHOR
Samaneh
Hosseini
samanehdr90@gmail.com
4
Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
AUTHOR
Cosh A, Carslaw H. Multiple sclerosis: symptoms and diagnosis. InnovAiT. 2014; 7(11): 651-7.
1
Dobson R, Giovannoni G. Multiple sclerosis - a review. European journal of neurology. 2019; 26(1):27-40.
2
Zadro I, Barun B, Habek M, Brinar VV. Isolated cranial nerve palsies in multiple sclerosis. Clinical neurology and neurosurgery. 2008;110(9): 886-8.
3
Ralli M, Stadio AD, Visconti IC, Russo FY, Orlando MP, Balla MP, et al. Otolaryngologic Symptoms in Multiple Sclerosis: A Review. Int Tinnitus J. 2018;22(2143-9).
4
Brinkmann V, Davis MD, Heise CE, Albert R, Cottens S, Hof R, et al. The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors. Journal of Biological Chemistry. 2002; 277(24):21453-7.
5
Oo ML, Thangada S, Wu MT, Liu CH, Macdonald TL,Lynch KR,et al. Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor. Journal of Biological Chemistry.2007 Mar 23;282(12):9082-9.
6
Matloubian M, Lo CG, Cinamon G, Lesneski MJ, Xu Y, Brinkmann V, et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature. 2004;427(6972):355-60.
7
Kappos L, Radue E-W, O'Connor P, Polman C, Hohlfeld R, Calabresi P, et al. A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis. New England Journal of Medicine. 2010;362(5):387-401.
8
Hatcher SE, Waubant E, Nourbakhsh B, Crabtree-Hartman E, Graves JS. Rebound Syndrome in Patients With Multiple Sclerosis After Cessation of Fingolimod Treatment. JAMA neurology. 2016;73(7):790-4.
9
Frau J, Sormani MP, Signori A, Realmuto S, Baroncini D, Annovazzi P, et al. Clinical activity after fingolimod cessation: disease reactivation or rebound? European journal of neurology. 2018;25(10):1270-5.
10
Kuhn M, Heman-Ackah SE, Shaikh JA, Roehm PC. Sudden sensorineural hearing loss: a review of diagnosis, treatment, and prognosis. Trends in amplification. 2011;15(3):91-105.
11
Atula S, Sinkkonen ST, Saat R, Sairanen T, Atula T. Association of multiple sclerosis and sudden sensorineural hearing loss. Multiple sclerosis journal - experimental, translational and clinical. 2016;2:2055217316652155-.
12
Tekin M, Acar GO, Cam OH, Hanege FM. Sudden sensorineural hearing loss in a multiple sclerosis case. Northern clinics of Istanbul. 2014;1(2):109-13.
13
Cadoni G, Agostino S, Scipione S, Cianfoni A. Sudden sensorineural hearing loss as presenting symptom of multiple sclerosis in a 15-year-old girl. International Journal of Pediatric Otorhinolaryngology Extra. 2006;1(2):97-9.
14
A. Di Stadio, L. Dipietro, M. Ralli, F. Meneghello, A. Minni, A. Greco, et al. Sudden hearing loss as an early detector of multiple sclerosis: a systematic review. Eur Rev Med Pharmacol Sci. 2018;22(14):4611-24.
15
Hellmann MA, Steiner I, Mosberg-Galili R. Sudden sensorineural hearing loss in multiple sclerosis: clinical course and possible pathogenesis. Acta neurologica Scandinavica. 2011;124(4):245-9.
16
Gupta R, Mohindroo NK, Azad R. Alternating sudden sensorineural hearing loss in demyelinating disorders. Indian Journal of Otology. 2016 Apr 1;22(2):123-5.
17
ORIGINAL_ARTICLE
Infraorbital Tuberculosis: A Case Report
Introduction:Extra-pulmonary tuberculosis (EPTB) arising in extra-oral region in head and neck are rare, and when swellings arise from other sites such as infraorbital region, cheek, etc, tuberculosis is not usually considered for the differential diagnosis (DD) and often the diagnosis is missed and appropriate treatment is delayed.Case Report:We report a rare entity of primary tuberculosis, which presented as infraorbital swelling and our technique of performing sublabial approach to the swelling with endoscopic guided excision of the swelling and also we have review of literature of similar cases of primary tuberculosis presenting as swelling over the face over the past 5 year.Conclusion:Primary EPTB should be considered as DD in cases of chronic facial swelling.
https://ijorl.mums.ac.ir/article_16031_78d70d19255695c6e2c940837a4e938a.pdf
2020-07-01
255
258
10.22038/ijorl.2020.43237.2422
Extra pulmonary primary tuberculosis
Infraorbital tuberculosis
Sublabial endoscopic approach
Rakesh
Bambore-Suryanarayan-Rao
rakes_bs@yahoo.com
1
Department of ENT, JSS Academy of higher education and research (JSSAHER), Mysuru, Karnataka.
AUTHOR
Bharathi
Murundi-Basavarajaiah
drmbbharathi@yahoo.co.in
2
Department of ENT, JSS Academy of higher education and research (JSSAHER), Mysuru, Karnataka.
LEAD_AUTHOR
Sreenivas-Kamath
Kasaragod
ksreenivask77@gmail.com
3
Department of ENT, JSS Academy of higher education and research (JSSAHER), Mysuru, Karnataka.
AUTHOR
Thanzeem
Unisa
thanzeem@gmail.com
4
Department of ENT, JSS Academy of higher education and research (JSSAHER), Mysuru, Karnataka.
AUTHOR
Sezer B, Zeytinoglu M, Tuncay U, Unal T. Oral mucosal ulceration: a manifestation of previously undiagnosed pulmonary tuberculosis. J Am Dent Assoc 1939. 2004 Mar; 135(3):336–40.
1
Shafer WG, Hine MK, Levy BM. A textbook of oral pathology. Philadelphia, Pa., [etc.: Saunders; 1974.
2
Sharma SK, Ryan H, Khaparde S, Sachdeva KS, Singh AD, Mohan A, et al. Index-TB guidelines: Guidelines on extrapulmonary tuberculosis for India. Indian J Med Res. 2017 Apr 1;145(4):448.
3
Global tuberculosis report 2017. Geneva: World Health Organization; 2017. Licence: CC BY-NCSA 3.0 IGO.
4
Schlossberg D, editor. Tuberculosis and nontuberculous mycobacterial infections. 6th ed. Washington, DC: ASM Press; 2011. 638 p.
5
Knezevic P, Knezevic B, Skerlev M, Uglesic V, Jankovic VK. Primary Tuberculosis of the Cheek skin: Difficulties in Diagnostic Procedure. Maced J Med Sci. 2009 Sep 1;2:235–8.
6
Namdev R, Jain M, Jindal A, Bodh M. Tuberculosis of the Cheek: A Rare Presentation. J Clin Pediatr Dent. 2015 Sep;39: 475–80.
7
Neena C, Deepak KG, Santosha R, Leelavathi D. Primary Tuberculosis of the Cheek: A Common Disease with a Rare Presentation: Malays J Med Sci. Jan-Feb 2014; 21(1): 66-68.
8
Saravanam PK, Singh U. Rare presentation of extra-pulmonary tuberculosis of the cheek: JMR 2016; 2(1): 3-5.
9
Karbach J, Thal SC, Weber A, Springer E, Eich A, Genitsariotis R, et al. Swelling of the Buccal Cheek: An Unusual Presentation of Primary Tuberculosis. J Oral Maxillofac Surg. 2007 Oct; 65: 2108–11.
10
Gupta M, Gupta M, Kaur R. Tuberculosis colliquativa cutis of the cheek: an extremely uncommon manifestation of primary extrapulmonary tuberculosis. BMJ Case Rep. 2013 Apr 16; 2013:bcr2013009058.
11
ORIGINAL_ARTICLE
Osseous Choriostoma of the Upper Lip
Introduction:Choristoma is a non-neoplastic growth of normal tissues in non-indigenous site of origin. Osseous Choristoma is an ectopic bone formation which is a rare entity with 72 cases has been reported in the tongue, 15 cases in the buccal mucosa, 1 case in the lower lip. Case Report:A 43 year old male patient experienced a mild, intermittent, dull aching type in the upper lip. An excisional biopsy was done by placing a single incision under local anesthesia. To our knowledge case is first to be reported in the upper lip as a result of reactive pathogenesis. Conclusion:As per literature, surgical excision is the treatment of choice for osseous Choristoma. Malignant transformation has not been reported yet.
https://ijorl.mums.ac.ir/article_16030_c79242f0d3bec5b136ed2547de71547c.pdf
2020-07-01
259
262
10.22038/ijorl.2020.41909.2387
Choriostoma
Mature bone
Osseous choriostoma
Osteocytes
Ashwin -Chandra
Veni
drashwinchandraveni2016@gmail.com
1
Department of Oral Medicine and Radiology, SRM Dental College, Chennai, Tamil Nadu, India.
LEAD_AUTHOR
Kannan
Asokan
kannan_mds@yahoo.co.in
2
Department of Oral Medicine and Radiology, SRM Dental College, Chennai, Tamil Nadu, India.
AUTHOR
Krithika-Chndrasekar
Sekar
krithika.sekar@gmail.com
3
Department of Oral Medicine and Radiology, SRM Dental College, Chennai, Tamil Nadu, India.
AUTHOR
Parimala
D
docparima@gmail.com
4
Department of Oral Medicine and Radiology, SRM Dental College, Chennai, Tamil Nadu, India.
AUTHOR
Kanmani
Shanmuga-sundaram
dockrk05@gmail.com
5
Department of Oral Medicine and Radiology, Chettinad Dental College, Chennai, Tamil Nadu.
AUTHOR
Yesoda
Aniyan
yesoda.aniyan@gmail.com
6
Department of Oral Medicine and Radiology, SRM Dental College, Chennai, Tamil Nadu, India.
AUTHOR
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