Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
33
3
2021
05
01
Impact of Narrow Band Imaging in Pre-Operative Assessment of Suspicious Oral Cavity Lesions: A Systematic Review
127
135
EN
Carmelo
Saraniti
0000-0002-1072-0736
ENT Clinic, Department of Biomedicine, Neurosciences and Advanced Diagnostic, University of Palermo, Palermo, Italy.
carmelo.saraniti@unipa.it
Giuseppe
Greco
0000-0001-7401-1421
ENT Clinic, Department of Biomedicine, Neurosciences and Advanced Diagnostic, University of Palermo, Palermo, Italy.
giuseppegreco1989@gmail.com
Barbara
Verro
0000-0002-1940-5281
ENT Clinic, Department of Biomedicine, Neurosciences and Advanced Diagnostic, University of Palermo, Palermo, Italy.
verrobarbara@gmail.com
Norhafiza Mat
Lazim
0000000223671814
Department of Otorhinolaryngology-Head & Neck Surgery, Universiti Sains Malaysia, Health Campus 16150, Kubang Kerian, Kelantan, Malaysia.
norhfiza@usm.my
Enzo
Chianetta
0000-0003-1343-9293
ENT Clinic, Department of Biomedicine, Neurosciences and Advanced Diagnostic, University of Palermo, Palermo, Italy.
enzo.chianetta@gmail.com
10.22038/ijorl.2021.51485.2746
Introduction:<br /> Narrow band imaging (NBI) is a powerful tool that allows visualizing the mucosal and submucosal vasculature. Among the available diagnostic techniques, NBI is one of the most valid for early detection of oral squamous cell carcinoma (OSCC).<br /> Materials and Methods:<br /> We carried out a bibliographic search in PubMed, Scopus and Web of Science databases using relevant keywords. Articles selected were screened by two independent authors based on inclusion and exclusion criteria. Nine papers were singled out according to the eligibility criteria and included in this review. We investigated the articles for pooled sensitivity, specificity, accuracy, positive predictive value and negative predictive value of pre-operative NBI.<br /> Results:<br /> The use of NBI examination in the oral cavity revealed higher specificity, sensitivity, positive and negative predictive values and accuracy compared to white light examination for the diagnosis of oral squamous cell cancer (OSCC). In addition, NBI has proved great utility in detecting malignancy features in oral pre-malignant lesions.<br /> Conclusions:<br /> This review shows that NBI is a powerful tool for examining oral suspicious lesions. Most of the articles examined revealed high values of sensitivity, specificity, positive predictive value, negative predictive value and accuracy in detection of oral malignant and pre-malignant lesions. Therefore, the use of NBI is highly recommended for the early detection of oral cancer and potentially malignant disorders. Future studies should seek to affirm the validity of NBI and in particular to standardize NBI classification.
Cancer,Erythroplakia,Leukoplakia,Narrow band imaging,Oral
https://ijorl.mums.ac.ir/article_17917.html
https://ijorl.mums.ac.ir/article_17917_388fba5a07649cbe971db37b65a4461c.pdf
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
33
3
2021
05
01
Tragal Perichondrium and Composite Cartilage Graft Complimenting Endoscopic Tympanoplasty in True Sense: A Comparison
137
142
EN
Arvind
Varma
0000-0003-44634972
Department of ENT, Shri Guru Ram Rai Institute of Medical and Health Science Patel Nagar, Dehradun.
drvarmaarvind@gmail.com
Chetan
Bansal
Senior Medical Officer ONGC Hospital Ballupur Dehradun.
chetanhitu@gmail.com
Virendra
Pratap
Singh
Senior Consultant, ENT, Max Superspeciality Hospital Mussorriee Road, Dehradun.
virenent@gmail.com
10.22038/ijorl.2021.48789.2613
Introduction:<br /> In days of scar less surgeries it has become necessary for otologists to concentrate on tympanoplasties without external incisions. This study compares the anatomical and functional results of tragal perichondrium graft and perichondrium-cartilage composite graft for transcanal endoscopic tympanoplasties in Himalayan region.<br /> Methods and Materials:<br /> This prospective study included 60 subjects of chronic otitis media (mucosal type), who underwent transcanal endoscopic underlay type I tympanoplasty and were divided into two groups. In 30 cases tragal perichondrium graft and in rest of 30 cases Tragal perichondrium Cartilage composite graft was used. Anatomical and functional outcomes were evaluated at 6 months time.<br /> Results:<br /> Hearing gain comparing Audiometric data between the tragal perichondrial graft group and tragal perichondrial cartilage composite graft group at 6 months showed no statistically significant differences (P= 0.9533). Assessment of anatomical outcome indicated a greater number of complications in the tragal perichondrial graft group although it was not statistically significant (P=0.6360 in anterior graft failure group , P =0.1322 in reperforation group and P= 0.1056 in retraction group). <br /> Conclusion:<br /> Functional results validated both the grafting material while anatomical results are slightly better in tragal perichondrial cartilage composite graft group in term of re perforation and retraction. More over [A1] with[A2] use of tragal grafts endoscopic tympanoplasty fulfils its true meaning as no visible scar and post operative patient morbidity is prevented.<br /> <br /> <br /> <br /> [A1]Moreover<br /> <br /> <br /> <br /> <br /> [A2]delete
Transcanal endoscopic,Tympanoplasty,Tragal
https://ijorl.mums.ac.ir/article_17918.html
https://ijorl.mums.ac.ir/article_17918_2c9e42a36cd3e0de8550da4ea797f58d.pdf
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
33
3
2021
05
01
Comparison of Titanium versus Polycel as Partial Ossicular Replacement Prosthesis: A Randomized Clinical Trial
143
149
EN
Mohammad
Faramarzi
0000-0002-6903-3252
Department of Otorhinolaryngology-Head and Neck Surgery, Shiraz University of Medical sciences, Shiraz, Iran.
Otolaryngology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
faramarzi@sums.ac.ir
Masih
Tale
Otolaryngology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
masihtale@yahoo.com
Sheida
Khosravaniardakani
0000-0002-4581-4134
Otolaryngology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
khosravash@sums.ac.ir
Sareh
Roosta
0000-0002-3927-0812
Otolaryngology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
roosta.sareh@gmail.com
Ali
Faramarzi
0000-0003-4814-1729
Otolaryngology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
ali_faramarzi@sums.ac.ir
10.22038/ijorl.2021.52321.2775
Introduction:<br /> Each type of prosthesis for ossiculoplasty has its advantages and disadvantages, and the choice of the best material has been a matter of various studies. The present study aimed to make a comparison between the hearing outcomes of partial ossicular replacement prosthesis (PORP) using titanium versus Polycel prosthesis.<br /> <strong> </strong><br /> Material and Methods:<br /> A total of 106 patients undergoing PORP as a second stage ossiculoplasty were analyzed in this study. Following that, they were randomly assigned to two groups of titanium (n=54) and Polycel (n=52) prosthesis. Subsequently, pre-and post-operative audiometric data were assessed based on the aim of the study.<br /> <br /> Results:<br /> In general, the post-operative air-bone gap within 20 dB was given to 63.5% and 55.6% of all ears in the Polycel and titanium groups, respectively, indicating a non-significant difference (P=0.407). Finally, no SNHL was observed in the groups.<br /> <br /> Conclusion:<br /> Overall, the hearing outcomes and the success rate of PORP are comparable between titanium and Polycel prostheses. Therefore, the selection of these prostheses could be based on the surgeons’ preferences, availability, and cost.
Hearing outcome,Ossiculoplasty,Partial ossicular replacement prosthesis,Polycel,Titanium
https://ijorl.mums.ac.ir/article_17919.html
https://ijorl.mums.ac.ir/article_17919_af75576f504ffd6988aac57339383ae2.pdf
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
33
3
2021
05
01
Neuromuscular Retraining versus BTX-A Injection in Subjects with Chronic Facial Nerve Palsy, A Clinical Trial
151
155
EN
Abbas Ali
Pourmomeny
0000-0002-1877-9089
Department of Physical Therapy, School of Rehabilitation Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
pourmomeny@rehab.mui.ac.ir
Elham
Pourali
Department of Physical Therapy, School of Rehabilitation Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
elhampourali.pt92@gmail.com
Ahmad
Cheatsaz
Department of Neurology, School of Medicine Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
chitsaz@med.mui.ac.ir
10.22038/ijorl.2021.41305.2347
Introduction: <br /> Chronic facial nerve palsy has long been known to negatively affect the quality of life in patients. The present study aimed to investigate the efficacy of Botulinum Toxin A (BTX-A) and neuromuscular retraining therapy (NMRT) in the symmetry of chronic facial palsy.<br /> Materials and Methods:<br /> Two groups, namely experimental and control, were considered each consisting of 13 patients. The study population included a total of 15 female subjects. The BTX-A was injected into the synkinetic muscle in the experimental group; nevertheless, the patients in the second group participated in special neuromuscular retraining. The rate of reducing synkinesis and symmetrical improvement was evaluated using the Facial Grading System (FGS) after 4 months of treatment. The independent t-test was performed to compare the two groups.<br /> Results:<br /> According totheSunnybrook FGS,the mean changes in Sunnybrook scores in the experimental and neuromuscular retraining groups were 3% and 24%, respectively. The comparison of the mean scores of the two groups was statistically significant after the interventions (P=0.033). A variable ratio of statistically significant improvement was observed in synkinesis in both groups following the treatment (P=0.041). In addition, by comparing the synkinesis scores between the two groups, the reduction of synkinesis was observed to be greater in the neuromuscular retraining group (P=0.041) after the treatment.<br /> Conclusions:<br /> The findings of the current study indicated that special neuromuscular retraining leads to significant improvement in the FGS score, compared to botulinum toxin therapy alone. Moreover, it was observed that facial symmetry can be treated with special neuromuscular retraining and the patient can overcome synkinesis.
Botulinum toxin A,Facial nerve palsy,Neuromuscular retraining,Synkinesis
https://ijorl.mums.ac.ir/article_17932.html
https://ijorl.mums.ac.ir/article_17932_b0c7bfde385738b24f924b99626a80fa.pdf
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
33
3
2021
05
01
Sensorineural Hearing Loss in Dengue: A Pilot Study
157
161
EN
Kapil
Soni
0000-0002-3586-6213
Department of Otorhinolaryngology, All India Institute of Medical Sciences, Jodhpur.
ksoni805@gmail.com
Gopal
Krishna
Bohra
Department of Medcine, All India Institute of Medical Sciences, Jodhpur.
bohra.gk@aiimsjodhpur.edu.in
Nithin
Prakasan
Nair
0000-0001-7342-9682
Department of Otorhinolaryngology, All India Institute of Medical Sciences, Jodhpur.
nithinprakasannair.2008@gmail.com
Darwin
Kaushal
0000-0001-7719-6409
Department of Otorhinolaryngology, All India Institute of Medical Sciences, Jodhpur.
drdarwin.aiims@gmail.com
Sourabha
Kumar
Patro
0000-0002-4819-7928
Department of Otorhinolaryngology, All India Institute of Medical Sciences, Jodhpur.
sourabhlipi@gmail.com
Amit
Goyal
0000-0002-4339-7541
Department of Otorhinolaryngology, All India Institute of Medical Sciences, Jodhpur.
meetugoyal@yahoo.com
10.22038/ijorl.2020.39874.2314
<strong>Introduction:</strong><br /> <strong>Association of hearing loss has been found with a couple of febrile illnesses. Dengue fever is an arboviral febrile illness that is transmitted by Aedes mosquito. A case of sensorineural hearing was documented in the literature recently in dengue haemorrhagic fever. We are aiming to find if hearing loss occurs in dengue patients.</strong><br /> <strong> </strong><br /> <strong>Methods and Methodology:</strong><br /> <strong>We assessed the hearing of ten patients diagnosed with Dengue fever from August 2018 to October 2018, prospectively. Patients who had a prior history of hearing loss or chronic suppurative otitis media were excluded from the study. Brief history, clinical examination and audiological assessment were made for all patients. All patients were followed up for three months with repeat audiological evaluation.</strong><br /> <strong> </strong><br /> <strong>Results:</strong><br /> <strong>Two patients complained of hearing loss after the onset of fever. They had a bilateral mild sensorineural hearing loss on audiological evaluation. One other patient was found to have bilateral high-frequency hearing loss although there was no complaint of hearing impairment. On three months follow up, both patients had bilateral mild sensorineural hearing loss with no improvement.</strong><br /> <strong> </strong><br /> <strong>Conclusion:</strong><br /> <strong>Hearing loss in dengue fever, even though being mild in nature is irreversible. The cause of hearing loss in dengue is yet to be found. For the definitive association of hearing loss in dengue fever further studies are required.</strong>
Dengue fever,Hearing Loss,Hearing test
https://ijorl.mums.ac.ir/article_17920.html
https://ijorl.mums.ac.ir/article_17920_3b028d32a637bd27db87c8ccfb3c04a5.pdf
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
33
3
2021
05
01
Olfactory Dysfunction in Patients Infected with 2019 Novel Coronavirus
163
171
EN
Mehdi
Bakhshaee
https://orcid.org/00
Sinus and Surgical Endoscopic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
mehbakhsh@yahoo.com
Maral
Barzegar-Amini
0000-0002-0834-2481
Allergy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
aminim1@mums.ac.ir
Zohreh
Motedayen
0000-0002-2843-9061
Department of Otolaryngology, Mashhad University of Medical Sciences, Mashhad, Iran.
drzment@gmail.com
Roshanak
Khojasteh-Taheri
0000-0002-6933-9817
Department of Microbiology, Faculty of Science, Neyshaboor Branch, Islamic Azad University, Neyshaboor, Iran.
Department of Research, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
khojastehr1@mums.ac.ir
Mahdi
Rafiee
Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
rafieem951@mums.ac.ir
Mahnaz
Amini
0000-0002-5205-4647
Lung Disease Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
aminim@mums.ac.ir
Parvaneh
Layegh
0000-0003-1920-9341
Department of Radiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
layeghpr@mums.ac.ir
Kamila
Hashemzadeh
Rheumatic Disease Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
hashemzadehk@mums.ac.ir
Delaram
Omidvar
Department of Internal Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
drdelaramomidvar@gmail.com
Peter
H. Hwang
Department of Rhinology & Endoscopic Skull Base Surgery, Stanford University School of Medicine, Palo Alto, California.
hwangph@stanford.edu
Masoomeh
Hosseinpoor
0000-0002-1754-2119
Department of Otolaryngology, Mashhad University of Medical Sciences, Mashhad, Iran.
hosseinpoorms@gmail.com
10.22038/ijorl.2021.51614.2750
Introduction:<br /> The current study aimed at investigating the occurrence and features of olfactory dysfunction in patients with confirmed coronavirus disease 2019 (COVID-19) infection.<br /> <br /> Materials and Methods:<br /> Patients with laboratory and clinically confirmed COVID-19 infection were enrolled in this longitudinal study. They were managed in either the inpatient or outpatient setting. The demographic, clinical, and outcome data were retrieved from patients’ medical records. Olfactory dysfunction features, including the onset pattern, duration, and recovery time were investigated. The visual analog scale (VAS) was utilized as a self-rating subjective measurement of olfactory function.<br /> <br /> Results:<br /> According to the results, the mean age of the patients (n=502) was obtained at 46.8±18.5 years; moreover, 52.4% and 47.6% of cases were female and male, respectively. It was also revealed that 35.4% and 64.5% of the subjects were outpatients and hospitalized, respectively. Based on the findings, 178 (38.4%) subjects had olfactory dysfunction. The mean values of VAS in hyposmic patients were estimated at 2.5±2.5, 8.3 ±2.1, and 9.4±1.6 at the first evaluation, in 2 weeks, and after 1 month of follow-up (p <0.001). The onset of olfactory dysfunction was more suddenly (58.7%). The majority of cases experienced olfactory dysfunction at the same time as other symptoms 72(51.1%). Based on the results, 0.4% of subjects infected with COVID-19 had olfactory dysfunction as an isolated symptom. The olfactory dysfunction was recovered after 2 weeks in 18 (25.3%) anosmic and 37(46.8%) hyposmic patients.<br /> <br /> Conclusion:<br /> Olfactory dysfunction seemed to be an important symptom of COVID-19 infection. The occurrence of this disturbance as a transient self-limited condition was significantly higher among female subjects.
COVID-19,Olfactory dysfunction,Smell disorder
https://ijorl.mums.ac.ir/article_17921.html
https://ijorl.mums.ac.ir/article_17921_bde4e33ae5366aa5d0b286cbc9d0f359.pdf
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
33
3
2021
05
01
Identification of a Novel WFS1 Mutation Using the Whole Exome Sequencing in an Iranian Pedigree with Autosomal Dominant Hearing Loss
173
176
EN
Javad
Mohammadi Asl
0000-0002-1750-0541
Noorgene Genetics Lab, Ahvaz, Iran.
mohammadi-asl@ajums.ac.ir
Nader
Saki
Hearing Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
saki@ajums.ac.ir
Masoud
Dehdashtiyan
Department of the Pediatrics, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
dehdashtiyan@ajums.ac.ir
Mostafa
Neissi
0000-0002-9359-2054
Department of Genetics, Khuzestan Science and Research Branch, Islamic Azad University, Ahvaz, Iran. Department of Genetics, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran.
iammostafaneissi@gmail.com
Farideh
Ghanbari Mardasi
0000-0002-9274-6592
Department of Medical Genetics, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
ghanbari246@gmail.com
10.22038/ijorl.2021.48471.2602
Introduction:<br /> Sensorineural hearing loss is the most frequent type of hearing impairment in the human population. Genetic factors account for over 60% of hearing loss in patients. This is a genetically heterogeneous sensorineural disorder.<br /> <br /> Case Report:<br /> We carried out whole exome sequencing (WES) to screen hearing loss candidate genes in a member of an Iranian family with hearing loss. The Sanger process was used to sequencing the variant in the family members. A novel mutation (c. 559C > T) was found in the WFS1 gene (in exon 5) in the patient leading to a heterozygous missense mutation (p.L187F). Furthermore, it co-segregated with HL in the family. All affected individuals in the family had severe-to-profound HL.<br /> <br /> Conclusion:<br /> This survey is the first to describe WFS1 related HL in the Iranian population. Our data propose that the WFS1-p.L187F mutation is the pathogenic variant for autosomal dominant nonsyndromic hearing loss. Our results extend the range of the WFS1 gene mutations.
Hearing Loss,Novel Mutation,Next Generation Sequencing (NGS),Whole Exome Sequencing (WES),WFS1
https://ijorl.mums.ac.ir/article_17922.html
https://ijorl.mums.ac.ir/article_17922_ea71f8fd2567df5374f6ac1f977ec54a.pdf
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
33
3
2021
05
01
Organized Hematoma of the Maxillary Sinus: Report of Two Cases
177
181
EN
Mohamed -Amin
Chaabouni
0000-0003-0880-1032
Department of Otolaryngology–Head and Neck Surgery, Habib Bourguiba Hospital, Sfax , Tunisia
University of Sfax.
medamin_chaabouni@yahoo.fr
Souha
Kallel
https://orcid.org/00
Department of Otolaryngology–Head and Neck Surgery, Habib Bourguiba Hospital, Sfax , Tunisia
University of Sfax.
souha.kallel@yahoo.fr
Rania
Kharrat
Department of Otolaryngology–Head and Neck Surgery, Habib Bourguiba Hospital, Sfax , Tunisia
University of Sfax.
kharratrania@yahoo.com
Ines
Kharrat
Department of Otolaryngology–Head and Neck Surgery, Habib Bourguiba Hospital, Sfax , Tunisia
University of Sfax.
inesk200@gmail.com
Manel
Mellouli
Department of Pathology, Habib Bourguiba University Hospital, Sfax, Tunisia.
mellouli.manel@yahoo.fr
Bouthaina
Hammami
Department of Otolaryngology–Head and Neck Surgery, Habib Bourguiba Hospital, Sfax , Tunisia
University of Sfax.
bouthainahk@gmail.com
Ilhem
Charfeddine
Department of Otolaryngology–Head and Neck Surgery, Habib Bourguiba Hospital, Sfax , Tunisia
University of Sfax.
ilhemecharfeddine@gmail.com
10.22038/ijorl.2021.48295.2594
Introduction:<br /> Organized hematoma of the maxillary sinus (OHMS) is a rare benign disease that can be locally aggressive. The diagnosis of this condition is challenging.<br /> <br /> Case Reports:<br /> We report two cases of OHMS presented with recurrent nasal bleeding, nasal obstruction and anosmia. Radiological findings were suggestive of a vascularised lesion in the first case and a malignant tumor of the maxillary sinus in the second case. Both patients underwent an endonasal endoscopic surgery<span style="text-decoration: line-through;">, </span>There was no recurrence at 19 months’ and six months’ follow-up respectively.<br /> <br /> Conclusions:<br /> OHMS should be included in the differential diagnosis if a patient presents with history of recurrent epistaxis and nasal obstruction and radiological findings reveal an expansible maxillary mass with or without bone erosion. Correct preoperative diagnosis is important to avoid unnecessary extensive surgery. The prognosis is very good and minimally invasive surgery such as endonasal endoscopic surgery can cure it completely.<br />
Epistaxis,Endonasal endoscopic surgery,Maxillary sinus,Nasal obstruction,Organized hematoma,Sinonasal tumor
https://ijorl.mums.ac.ir/article_17924.html
https://ijorl.mums.ac.ir/article_17924_5d3c807ad39ecd72d1e6724428b42686.pdf
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
33
3
2021
05
01
Zygomatico-Coronoid Pseudoarthrosis Due to Osteochandroma of Coronoid Process: A Rare Entity
183
186
EN
Mehtab
Alam
0000-0002-5866-1691
Department of Otorhinolaryngology, Faculty of Medicine, Aligarh Muslim University, Aligarh, India.
mehtabalam4105@gmail.com
Syed
Abrar
Hasan
Department of Otorhinolaryngology, Faculty of Medicine, Aligarh Muslim University, Aligarh, India.
profahasan@yahoo.com
Kamlesh
Chandra
Department of Otorhinolaryngology, Faculty of Medicine, Aligarh Muslim University, Aligarh, India.
kamleshchandra56@rediffmail.com
10.22038/ijorl.2021.48888.2617
Introduction:<br /> Osteochondroma of the coronoid process also known as Jacob’s disease, has rarely been reported in the literature and it posses a challenge as diagnosis may be overlooked in favour of other causes of limited mouth opening.<br /> <br /> Case Report:<br /> This is a case report of an adult male patient who presented with restricted mouth opening in whom radiological imaging, especially 3D computed tomography, played a role in establishing the diagnosis of Jacob’s disease.<br /> <br /> Conclusion:<br /> An osteochondroma of the coronoid process of the mandible (Jacob’s disease) is a rare cause of restricted mouth opening and its diagnosis can be overlooked in favour of TMJ ankylosis. The CT scan plays an important role in diagnosis and in planning for surgery.
Jacob’s disease,osteochondroma,Temporo-mandibular disorders,3D computed tomography,coronoidectomy
https://ijorl.mums.ac.ir/article_17926.html
https://ijorl.mums.ac.ir/article_17926_c51093d85f74063c0712b57ca58273bb.pdf
Mashhad University of Medical Sciences (MUMS)
Iranian Journal of Otorhinolaryngology
2251-7251
2251-726X
33
3
2021
05
01
“Incidental Papillary Thyroid Cancer in Thyroglossal Duct Cyst”: A Case Report
187
190
EN
José-Luis
Saavedra-Leveau
Head, Neck and Maxillofacial Surgery Service, Hospital Nacional Dos de Mayo, Lima-Perú, Universidad Nacional Mayor de San Marcos, Lima-Perú.
joseluis_saavedraleveau@yahoo.com
Silvana-Lucia
Chang-Grozo
Head, Neck and Maxillofacial Surgery Service, Hospital Nacional Dos de Mayo, Lima-Perú, Universidad Nacional Mayor de San Marcos, Lima-Perú.
silvanachang5@hotmail.com
Melissa
Elvita
Dominguez-Prado
Head, Neck and Maxillofacial Service, Hospital Central Policía Nacional del Perú.
melidp18@gmail.com
Luis-Alfredo
Ticona-Zegarra
Head, Neck and Maxillofacial Service, Hospital Nacional de Salud del Niño, Breña.
lt_2006@hotmail.com
10.22038/ijorl.2021.46922.2565
Introduction:<br /> Papillary thyroid cancer (PTC) in thyroglossal duct cyst (TGDC) is an infrequent condition with less than two hundred cases described in literature, with an incidence likely to be close to 1%. While its management is quite straightforward, there exists significant controversy regarding whether additional treatment is needed to manage incidentally noticed carcinoma in TGDCs.<br /> <strong> </strong><br /> Case Report:<br /> A 37-years-old man came to us complaining of a slowly progressive neck mass located in the midline from 4 years ago. Ultrasonography (US) showed a mixed tumor with cyst predominance of 90x79x50 mm and Computed-Tomography (CT) revealed a mixed inframentonian heterogeneous tumor associated with small, mostly peripheral calcifications. The mass was resected using Sistrunk’s surgery. Histologic review reported a moderately differentiated papillary carcinoma in thyroglossal duct cyst, without vascular and lymphatic invasion. After two months, a total thyroidectomy was done, to which the pathological report informed normal thyroid.<br /> <br /> Conclusion:<br /> Thyroglossal duct cyst carcinoma is a rare entity. Management should be decided on single risk stratification. In all cases, a Sistrunk surgery would be accomplished in order to remove the tumor. The reason for thyroidectomy in individuals with a normal thyroid is due to the probability of presenting an intraglandular thyroid cancer concomitantly. It also enables the management with radio-iodine and patient follow up by quantifying thyroglobulin levels.
Head And Neck Cancer,surgical management,Thyroglossal duct cyst,Thyroid cancer
https://ijorl.mums.ac.ir/article_17927.html
https://ijorl.mums.ac.ir/article_17927_c5a214a1f78bc469a156d70640d97f49.pdf