Giant Thyroid Fibrosarcoma- A Case Report

Document Type : Case Report


Department of Otorhinolaryngology, Gregorio Marañón Hospital, Madrid, SPAIN.


Thyroid gland fibrosarcomas are extremely rare tumors, and only very few cases have been described in the literature. There are no set recommendations along with follow-ups regarding the treatment of these tumors. Moreover, the prognosis is poor with a very short life expectancy.
Case Report:
We present an 81-year-old patient who was suffering from increasing dysphagia and dysphonia related to a painless giant cervical mass, which presented with progressive growth for the preceding months. After a core needle biopsy with a suspicion of a solitary fibrous tumor, total excision of the tumor was successfully performed, and the pathology examination revealed a fibrosarcoma. Following surgery, radiotherapy was decided in the oncological multidisciplinary meeting; however, the patient refused it. There were neither new clinical symptoms nor tumor recurrence after an 18-month follow-up.
Although it is a very rare tumor, primary fibrosarcoma of the thyroid gland should be kept in mind in the differential diagnosis of neck tumors.


  1. Buła G, Waler J, Niemiec A, Trompeta J, Steplewska K, Gawrychowski J. Unusual malignant thyroid tumours: a clinical study of 20 cases. Acta Chir Belg 2008; 108: 702–7.
  2. Surov A, Gottschling S, Wienke A, Meyer H, Spielmann R, Dralle H. Primary thyroid sarcoma: a systematic review. Anticancer Res. 2015; 35(10): 5185-91.
  3. Melak T, Mathewos B, Enawgaw B, Damtie D. Prevalence and types of thyroid malignancies among thyroid enlarged patients in Gondar, Northwest Ethiopia: a 3-year institution based retrospective study. BMC Cancer 2014; 2:899–903.
  4. Janczak D, Chabowski M, Pawelczyk J, Jelen M, Szydelko T. A Giant Primary Thyroid Fibrosarcoma in an Octogenarian. Chirurgia (2013) 108:568-70.
  5. Titi S, Sycz K, Umiński M. Primary fibrosarcoma of the thyroid gland-a case report. Pol J Pathol. 2007;58(1):59-62.
  6. Shi H, Wang C, Wei L, Lu S, Cao D. Malignant mesenchymoma of the thyroid: case report and literature review. Tumori. 2010; 96(2): 345-48.
  7. Bahadir MV, Girgin S, Goya C, Buyukbayram H, Urakci Z. Rare Undifferentiated Tumour of Thyroid: Primary Thyroid Fibrosarcoma. Journal of clinical & diagnostic research 2016, 10(6): PD30–PD31.
  8. Darouassi Y, Attifi H, Zalagh M, Rharrassi I, Benariba F. Myxofibrosarcoma of the thyroid gland. Eur Ann Otorhinolaryngol Head Neck Dis. 2014; 131(6): 385-87.