A case report of kikuchi’s disease

Document Type : Case Report

Authors

1 Infectious disease specialist

2 Specialist in the Department of Otorhinolaryngology, Mashhad University of Medical Sciences

3 pathologist

4 Infectious diseases assistant

Abstract

Introduction: Kikuchi's disease is a necrotizing lymphadenitis that is prevalent in Japan and is being increasingly recognized in other areas of the world. It usually occurs in women in their late 20s or early 30s and manifests as a posterior cervical adenopathy. It resolves spontaneously, usually over a period of several weeks to 6 months. Its initial clinical appearance is commonly similar to that of a lymphoma, and it can be pathologically misdiagnosed as such. Case report: We report a case of Kikuchi's disease that occurred in a 51-year-old Iranian woman. We discuss the clinical features, differential diagnosis, and pathology of this case in an effort to assist otolaryngologists in diagnosing this benign and uncommon entity.

Keywords


1- Kikuchi M. Lymphadenitis showing focal reticulum cell hyperplasia with  nuclear debris and phagocytes. Acta Hematol Jpn 1972; 35:379-80.
2- Fujimoto Y, Kozima Y, Yamaguchi K. Cervical subacute necrotizing lymphadenitis. A new clinicopathological entity. Naika 1972; 30:920-7.
3- Gleeson MJ, Siodlak MZ, Barbatis C, Salama NY. Kikuchi’s disease-A new cause of cervical lymphadenopathy. J Laryngol Otol 1985; 99(9): 935-9.
4- Zar R, Mcclintock C. Kikuchi- Fujimoto disease: A case report and review of literature. Clin Med 2007; 7(1): 82-4.
5- Poulose V, Chiam P, Poh WT. Kikuchi’s disease: a Singapore case series. Singapore Med J 2005; 46(5): 229-32.