Iranian Journal of Otorhinolaryngology

Iranian Journal of Otorhinolaryngology

Verruciform Xanthoma of the Ventral Surface of the Tongue: A Rare Case Report and Literature Review

Document Type : Case Report

Authors
Saedeh Atarbashi Moghadam 1
Ali Lotfi 2
Farnoush Kabiri 3
Soran Sijanivandi 4
1 Department of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Department of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3 Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
4 Dental Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
10.22038/ijorl.2020.45912.2506
Abstract
Introduction:
Verruciform xanthoma (VX) is an uncommon benign lesion with the subepithelial accumulation of foamy histiocytes and superficial papillary proliferations with a bright orange hue. This lesion exhibits an oral region predilection.Its clinical differential diagnosis includes verrucous leukoplakia, verrucous carcinoma, squamous papilloma, verruca vulgaris, condyloma accuminatum, squamous cell carcinoma, and fibroepithelial polyp.
 
Case Report:
This report presents a case of VX of the ventral surface of the tongue afflicting a 33-year-old otherwise healthy male.
Conclusion:
This case report can be valuable as a consequence of VX rarity and the similarity of its clinical features to papillary lesions. A biopsy is required for its definite diagnosis particularly when it occurs at sites with a high-risk of squamous cell carcinoma development, such as the lateral border and ventral surface of the tongue.
Keywords
Benign
Oral cavity
Tongue
Verruciform xanthoma
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Iranian Journal of Otorhinolaryngology
Volume 33, Issue 1
January and February 2021
Pages 55-59