Radiofrequency VS Cold Surgery to Treat Oral Papillomatous Lesions

Document Type : Original

Authors

1 Department of Otorhinolaryngology, A.O.U.P. Paolo Giaccone, Via del Vespro, 129, 90127 Messina, Italy.

2 Department of Dentistry, University of Barcelona, Barcelona, Spain.

3 Department of Otorhinolaryngology, A.O.U.P. Paolo Giaccone, Via del Vespro, 129, 90127 Palermo, Italy.

Abstract

Introduction:
The aim of this study is to analyse different surgery (radio frequency and cold instrumentation) of oral benign papillomatous lesions.
 
Materials and Methods:
A retrospective study was carried out in our section of Otorhinolaryngology from 2014 to 2018. 112 patients with oral benign papillomatous lesions were enrolled and divided into 2 groups. Group A of 62 patients treated with excision of lesions using radio frequency using a bipolar coagulation electrode (CelonLabENT). Group B of 50 patients treated with excision of the lesion using traditional cold instruments (scalpel and surgical forceps). All patients were evaluated for intraoperative bleeding, discomfort and recurrence rate.
 
Results:
112 patients (of which 37 males and 75 females) with mean age 32.9 ranged from 10 to 61 years. The HPV types associated with oral benign papillomatous lesions were HPV 6 (17%), 11 (23,3%), 13 (10,7%), 32 (34%), 2 (10%) and 57 (5%). There are no statistically significant differents among patients operated with radio frequency (Group A) and cold instrumentation (Group B) regarding intraoperative bleeding (P= 0.08), recurrence rate after 1 year from surgery (P=1), intraoperative discomfort (P=0.7) and postoperative discomfort (P=0.6).
 
Conclusion:
Radiofrequencies and surgery with scalpel and surgical forceps are equal valid methods for the treatment of benign papillomatous.

Keywords

References

  1. Prabhu SR, Wilson DF. Human papillomavirus and oral disease - emerging evidence: a review. Aust Dent J. 2013 Mar;58(1):2-10
  2. Atighechi S, Meybodian M, Dadgarnia MH, Baradaranfar MH, Behniafard N. Investigating the Prevalence of Human Papilloma Virus in Squamous Cell Carcinoma of the Larynx and Its Correlation with Disease Prognosis. Iran J Otorhinolaryngol. 2016 May; 28(86):197-202.
  3. Mardani M, AndisheTadbir A, Ranjbar MA, Khademi B, Fattahi MJ, Rahbar A. Serum Endostatin Levels in Oral Squamous Cell Carcinoma. Iran J Otorhinolaryngol. 2018 May; 30(98):125-130.
  4. Nikakhlagh S, Saki N, Shoar MH, Sartipipor A, Saki S. Incidence of etiologic factors in squamous cell carcinoma of head and neck in ahvaz. Iran J Otorhinolaryngol. 2012 Spring; 24(67):85-90.
  5. Valls-Ontañón A, Hernández-Losa J, Somoza Lopez de Haro R, Bellosillo-Paricio B, Ramón Y Cajal S, Bescós-Atín C et al. Impact of human papilloma virus in patients with oral and oropharyngeal squamous cell carcinomas. Med Clin (Barc). 2019 Mar 1;152(5):174-180.
  6. Freni F, Galletti B, Bruno R, Martines F, Abita P, Gazia F et al. Multidisciplinary approach in the removal of post-trauma foreign bodies in the head and neck district: cases report and review of literature. Acta Medica Mediterranea, 2019, 35: 405
  7. Mucia M, Salvago P, Brancato A, Cannizzaro C, Cannizzaro E, Gallina S et al. Upper respiratory tract infections in children: From case history to management. Acta Medica Mediterranea, 2015,
    31: 419.
  8. Snietura M, Lamch R, Kopec A, Waniczek D, Likus W, Lange D et al. Oral and oropharyngealpapillomas are not associated with high-risk human papillomavirus infection. Eur Arch Otorhinolaryngol. 2017 Sep;274(9):3477-3483.
  9. Castro TP, BussolotiFilho I. Prevalence of human papillomavirus (HPV) in oral cavity and oropharynx. Braz J Otorhinolaryngol. 2006 Mar-Apr; 72(2):272-82.
  10. Donà MG, Pichi B, Rollo F, Gheit T, Laquintana V, Covello R. Mucosal and cutaneous human papillomaviruses in head and neck squamous cell papillomas. Head Neck. 2017 Feb;39(2):254-259
  11. Alan H, Agacayak S, Kavak G, Ozcan A. Verrucous carcinoma and squamous cell papilloma of the oral cavity: Report of two cases and review of literature. Eur J Dent. 2015 Jul-Sep;9(3):453-6.
  12. Misir AF, Demiriz L, Barut F. Laser treatment of an oral squamous papilloma in a pediatric patient: a case report. J Indian SocPedodPrev Dent. 2013 Oct-Dec; 31(4):279-81.
  13. Boj J, Hernandez M, Espasa E, Espanya A. Oral focal fibrous hyperplasia and squamous cell papilloma treated with an erbium laser. Case presentation. Refuat Hapeh Vehashinayim (1993). 2014 Jan; 31(1):9-14,59.
  14. Pesántez J, Romero V, Lafebre F, Vazquez V, Reinoso J. Squamous papilloma in the oral cavity: case presentation and review of the literature. J Dent Health Oral DisordTher. 2018;9(4):257‒260.
  15. Orrù G, Mameli A, Demontis C, Rossi P, Ratto D, Occhinegro A et al. Oral human papilloma virus infection: an overview of clinical-laboratory diagnosis and treatment. Eur Rev Med Pharmacol Sci. 2019 Sep;23(18):8148-8157.
  16. Toledano-Serrabona J, López-Ramírez M, Sánchez-Torres A, España-Tost A, Gay-Escoda C. Recurrence rate of oral squamous cell papilloma after excision with surgical scalpel or laser therapy: A retrospective cohort study. Med Oral Patol Oral Cir Bucal. 2019 Jul 1;24(4):e433-e437.
  17. Sivapathasundharam B, Shifa S. Oral verruca vulgaris: report of a rare case. Indian J Dent Res. 2004 Jan-Mar;15(1):32-4.
  18. Fusconi M, Grasso M, Greco A, Gallo A, Campo F, Remacle M et al. Recurrent respiratory papillomatosis by HPV: review of the literature and update on the use of cidofovir. Acta OtorhinolaryngolItal. 2014 Dec;34(6):375-81.
  19. Pagliuca G, Martellucci S, Degener AM, Pierangeli A, Greco A, Fusconi M et al. Role of Human Papillomavirus in the Pathogenesis of Laryngeal Dysplasia. Otolaryngol Head Neck Surg. 2014 Jun;150(6):1018-23.
  20.   Gazia F, Galletti B, Freni F, Bruno R, Sireci F, Galletti C, et al. Use of intralesional cidofovir in the recurrent respiratory papillomatosis: a review of the literature. Eur Rev Med Pharmacol Sci. 2020 Jan; 24(2):956-962.
  21. Galletti F, Freni F, Gazia F, Gallo A. Vocal cord surgery and pharmacological treatment of a patient with HPV and recurrent respiratory papillomatosis. BMJ Case Rep. 2019 Nov 14;12(11). pii: e231117.
  22. Di Luca M, Iannella G, Montevecchi F, Magliulo G, De Vito A, Cocuzza S, et al. Use of the transoral robotic surgery to treat patients with recurrent lingual tonsillitis. Int J Med Robot. 2020 Aug; 16(4):e2106.
  23. Canevari FR, Montevecchi F, Galla S, Sorrentino R, Vicini C, Sireci F. Trans-oral robotic surgery for a Ewing's sarcoma of tongue in a pediatric patient: a case report. Braz J Otorhinolaryngol. 2020 Dec;86 Suppl 1:26-29.

 

 

 

 

 

 

Iranian Journal of Otorhinolaryngology
Volume 33, Issue 2
March and April 2021
Pages 87-91

Files

Share

How to cite

Statistics