Laryngeal Myxoma: A rare localization

Document Type : Case Report


1 Department of Otorhinolaryngology, Habib Bourguiba Hospital, University of Sfax, Sfax, Tunisia.

2 Department of Pathology, Habib Bourguiba Hospital, University of Sfax, Sfax, Tunisia.

3 Department of Pathology, Habib Bourguiba hospital, Sfax, Tunisia University of Sfax, Sfax, Tunisia


Myxomas are benign mesenchymal neoplasms which arise mainly in the heart. The laryngeal localization is very rare. We aim to describe the clinical, histological and therapeutic features of this condition.
Case Report:
We report two cases of laryngeal myxomas occurred in male and female patients, presenting with a history of prolonged hoarseness. Laryngoscopy revealed a polypoid mass on the true vocal folds. The lesions were excised with cold instruments. One patient presented a recurrence 4 years after the first surgery.
Laryngeal myxoma should be considered in case of a benign looking vocal fold lesion, especially a vocal cord polyp. Histologic exam is the only tool to confirm the diagnosis. It is treated by surgical resection. In the literature, recurrence is rare in laryngeal site, but patients need to be kept on close follow-up.


Main Subjects

  1. Mesolella M, Petruzzi G, Salzano FA, Lamarca S, Cieri M, Russo D, et al. Multidisciplinary management of a giant and obstruc-tive laryngeal myxoma. Otorinolaringol 2019;69:204-8
  2. Panda S, Kumar R, Gopinath VR, Sagar P. Head and Neck Myxoma Presenting as Isolated Laryngeal Polyp. Case Rep Otolaryngol. 2018;2018.
  3. Imaizumi M, Tada Y, Tani A, Ikeda M, Nakaegawa Y, Omori K. Two Cases of Laryngeal Myxoma Misdiagnosed as a Vocal Fold Polyp. J Otol Rhinol 2018; 7 :1.


  1. Tang CG, Monin DL, Puligandla B, Cruz RM. Glottic myxoma presenting as chronic dysphonia: a case report and review of the literature. Ear Nose Throat J. 2015;94(1):E30‐E33.
  2. Ritchie A, Youngerman J, Fantasia JE, Kahn LB, Cocker RS. Laryngeal myxoma: a case report and review of the literature. Head Neck Pathol. 2014;8(2):204-8.
  3. Hong YT, Hong KH. Localized Laryngeal Myxoma: Laryngoscopic Features. Ear Nose Throat J. 2020;99(5):NP56‐NP57.
  4. Val-Bernal JF, Martino M, Longarela MY. Cellular Myxoma of the Vocal Cord: A Case Report and Review of the Literature. Turk Patoloji Derg. 2020;36(1):77‐81.
  5. Nakamura A, Iguchi H, Kusuki M, Yamane H, Matsuda M, Osako S. Laryngeal myxoma. Acta Otolaryngol. 2008;128(1):110-2.
  6. Williams L, Allen C. A Submucosal True Vocal Fold Mass. JAMA Otolaryngol Head Neck Surg. 2015;141(11):1025-6.