Laryngeal lymphoma in a child – Case report and review of literature

Document Type : Case Report

Authors

1 Associate Professor, Division of Pediatric Hemato Oncology, Department of Pediatrics, Sri Ramachandra Institute of Higher Education and Research, Chennai 600 116.

2 First year Postgraduate, Department of ENT Head and Neck surgery, Sri Ramachandra Institute of Higher Education and Research.

3 Professor, Department of ENT , Head and Neck Surgery, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai

4 MD, DNB ,MNAMS Pathology, Head, Department of Pathology , Sri Ramachandra Institute of Higher Education and Research

Abstract

Abstract

Head and neck is the second most common region for lymphomas. Extranodal lymphomas of the larynx are rare in the pediatric population. Non Hodgkin Lymphoma (NHL)of the larynx is common in the supraglottic region as its rich in lymphoid tissue. They may present with dysphagia, dysphonia, snoring and progressive respiratory distress. Early visualization of the larynx is essential in such cases for appropriate diagnosis to improve the survival rates.

Case report

We present a case of 9 year old boy who presented with a change in voice, snoring and feeding difficulties for one year. Video laryngoscopy revealed globular mass arising from the epiglottis. He underwent excision biopsy and by immunohistochemistry was diagnosed to have Diffuse large B cell lymphoma. He was treated with chemotherapy and the child is clinically well in the follow-up, 1 year after the completion of therapy.

Conclusion

Although primary lymphomas of the larynx in children are rare, a high index of clinical suspicion is warranted to avoid diagnostic delays to initiate appropriate management to have better outcomes.

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