Laryngeal Lymphoma in a Child – Case Report and Review of Literature

Document Type : Case Report

Authors

1 Department of ENT, Sri Ramachandra Institute of Higher Education and Research.

2 Department of ENT, Head and Neck Surgery, Sri Ramachandra Institute of Higher Education and Research.

3 Associate Professor, Division of Pediatric Hemato Oncology, Sri Ramachandra Institute of Higher Education and Research.

4 Pathology, Head, Department of Pathology, Sri Ramachandra Institute of Higher Education and Research.

Abstract

Introduction:
Head and neck is the second most common region for lymphomas. Extranodal lymphomas of the larynx are rare in the pediatric population. Non Hodgkin Lymphoma (NHL) of the larynx is common in the supraglottic region as its rich in lymphoid tissue. They may present with dysphagia, dysphonia, snoring and progressive respiratory distress. Early visualization of the larynx is essential in such cases for appropriate diagnosis to improve the survival rates.
Case Report:
We present a case of 9 year old boy who presented with a change in voice, snoring and feeding difficulties for one year. Video laryngoscopy revealed globular mass arising from the epiglottis. He underwent excision biopsy and by immunohistochemistry was diagnosed to have diffuse large B cell lymphoma. He was treated with chemotherapy and the child is clinically well in the follow-up, 1 year after the completion of therapy.
Conclusions:
Although primary lymphomas of the larynx in children are rare, a high index of clinical suspicion is warranted to avoid diagnostic delays to initiate appropriate management to have better outcomes.

Keywords

Main Subjects

References

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Iranian Journal of Otorhinolaryngology
Volume 34, Issue 6
November and December 2022
Pages 337-341

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