Does Obstructive Sleep Apnea Syndrome Have Negative Effects on Hearing?

Document Type : Original

Authors

1 Istanbul Health Sciences University,Bursa Yuksek Ihtisas Training and Research Hospital, ENT Dept.

2 Istanbul Health SCiences University, Bursa Yuksek Ihtisas Training and Research Hospital, ENT Dept.

3 Istanbul Health Sciences University, Bursa Yuksek Ihtisas Training and Research Hospital, Chest Diseases.

Abstract

Introduction:
The our aim was to research the occurrence of hearing loss associated with the effect of hypoxemia on inner ear structures owing to sleep apnea syndrome and to designate the timely signs of cochlear injury.
Materials and Methods:
Participants diagnosed with probable sleep-disordered breathing among 63 patients, who experienced polysomnographic examination, were unexcluded in the present study. Control and study groups were structured in four groups pursuant to the apnea-hypopnea index and an intergroup comparison of audiometric parameters was performed. Accordingly, the apnea-hypopnea index, speech discrimination scores, speech recognition thresholds, and pure tone thresholds were compared.
Results:
A comparison of the obstructive sleep apnea groups by the degree of hearing loss indicated that there were significant differences by the average pure tone audiometry, average speech recognition thresholds, and average speech discrimination scores in both ears between the four groups (p<0.001).
Conclusion:
The results of the study proposed that intermittent hypoxemia due to obstructive sleep apnea syndrome might have adverse effects on both the speech discrimination and hearing.

Keywords

References

  1. Martines F, Ballacchino A, Sireci F, Mucia M, La Mattina E, Rizzo S et al. Audiologic profile of OSAS and simple snoring patients: the effect of chronic nocturnal intermittent hypoxia on auditory function. Eur Arch Otorhinolaryngol 2015; 273: 1419-24. https://doi.org/1007/s004050153714-6
  2. Karkoulias K, Lykouras D, Sampsonas F, Karaivazoglou K, Sargianou M, Drakatos P et al. The impact of obstructive sleep apnea syndrome severity on physical performance and mental health. The use of SF-36 questionnaire in sleep apnea. Eur Rev Med Pharmacol Sci 2013;17:531–36.
  3. Lurie A. Obstructive sleep apnea in adults: epidemiology, clinical presentation, and treatment options. Adv Cardiol 2011;46:1–42. https:// doi. org/10.1159/000327660
  4. Schwartz RN, Payne RV, Hier MP, Fanous A, Vallée-Gravel C. The relationship between upper airway collapse and the severity of obstructive sle­ep apnea syndrome: a chart review. Otolaryngol Head Neck Surg 2015;44:32. https:/ /doi.org/10. 1186/s 40463-015-0086-2
  5. Casale M, Vesperini E, Potena M, Pappacena M, Bressi F, Baptista PJ et al. Is obstructive sleep apnea syndrome a risk factor for auditory pathway? Sleep Breath 2012;16:413–7. https:// doi.org/10. 1007/s 11325-011-0517-x
  6. Chopra A, Jung M, Kaplan RC, Appel DW, Dinces EA, Dhar S et al. Sleep apnea is associated with hearing impairment: the hispanic community health study/study of Latinos. J Clin Sleep Med 2016;12(5):719–26. https:// doi. org/10. 5664/j csm. 5804.
  7. Newman AB, Nieto FJ, Guidry U, Lind BK, Redline S, Pickering TG et al. Relation of sleep-disordered breathing to Cardiovascular Disease Risk. The Sleep Heart Health Study. Am J Epidemiology 2001;154:50–9. https://doi. org/10. 1093/aje/154.1.50
  8. Bradley TD, Floras JS. Obstructive sleep apnoea and its cardiovascular consequences. Lancet 2009;373:82–93. https://doi.org/10.1016/S0140-6736(08)61622-0
  9. Fletcher EC. The relationship between systemic hypertension and obstructive sleep apnea: facts and theory. Am J Med 1995;98:118–28. https:// doi.org/ 10. 1016/S0002-9343(99)80395-7
  10. American Academy of Sleep medicine Task Force. Sleeprelated breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force. Sleep 1999;22:667-89.
  11. Kayabasi S, Iriz A, Cayonu M, Cengiz B, Acar A, Boynuegri S et al. Vestibular functions were found to be impaired in patients with moderate-to-severe obstructive sleep apnea. Laryngoscope 2015; 125:1244–8. https://doi.org/10.1002/lary.25021
  12. Sowerby LJ, Rotenberg B, Brine M, George CF, Parnes LS. Sleep apnea, daytime somnolence, and idiopathic dizziness—a novel association. Laryngoscope 2010;120:1274–8. https ://doi. org/ 10.1002/lary.20899
  13. Kayabasi S, Hizli O, Yildirim G. The association between obstructive sleep apnea and hearing loss: a cross‑sectional analysis. Eur Arch Otorhinolaryngol 2019;276:2215–21. https://doi.org/10.1007/s00405-019-05468-8
  14. Iriz A, Duzlu M, Kokturk O, Kemaloglu YK, Eravci FC, Kuukunal IS et al. The effect of obstructive sleep apnea syndrome on the central auditory system. Turk J Med Sci 2018;48:5–9.
  15. Seo YJ, Ju HM, Lee SH, Kwak SH, Kang MJ, Yoon JH et al. Damage of inner ear sensory hair cells via mitochondrial loss in a murine model of sleep apnea with chronic intermittent hypoxia. Sleep 2017;40(9):1–7
  16. Somers VK, Mark AL, Zavala DC, Abboud FM. Influence of ventilation and hypocapnia on sympathetic nerve responses to hypoxia in normal humans. J Appl Physiol 1989;67(5):2095-100. https://doi.org/10.1152/jappl.1989.67.5.2095
  17. Somers VK, Dyken ME, Clary MP, Abboud FM. Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest 1995;96(4):1897–904.
  18. Huang J, Marcus CL, Davenport PW, Colrain IM, Gallagher PR, Tapia IE. Respiratory and auditory cortical processing in children with obstructive sleep apnea syndrome. Am J Respir Crit Care Med 2013;188(7):852-7.
Iranian Journal of Otorhinolaryngology
Volume 35, Issue 1
January and February 2023
Pages 13-20

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