Life-Threatening Bleeding in Atypical Pleomorphic Adenoma of the Soft Palate

Document Type : Case Report

Authors

Division of Otorhinolaryngology, Department of Surgical Sciences, University of Turin, Via Genova 3, Turin, Italy.

10.22038/ijorl.2024.75295.3538

Abstract

Introduction:
Atypical pleomorphic adenoma (PA) is an uncommon tumor, more frequent in submandibular and parotid glands. PA is classified as atypical when it presents hypercellularity, necrosis or hyalinization, dysplasia, capsular violation or distant metastases.
Case Report:
We described a case of a 39-year-old female presented with a slowly growing mass involving the soft palate. A life-threatening bleeding from PA with hemorrhagic shock occurred and required ligation of the external carotid artery with tracheotomy. A transoral en-bloc excision of the mass (70 x 50 x 40 mm) was performed. Pathological exam demonstrated an atypical PA, with hypercellular fields and myoepithelial and squamous differentiation.
Conclusion:
An appropriate diagnostic evaluation and a prompt intervention are essential to avoid dangerous complications, even for benign neoplasms.

Keywords

Main Subjects


  1. Sahoo NK, Rangan MN, Gadad RD. Pleomorphic adenoma palate: major tumor in a minor gland. Ann Maxillofac Surg. 2013;3(2):195-7.
  2. Forde CT, Millard R, Ali S. Soft palate pleomorphic adenoma of a minor salivary gland: an unusual presentation. Case Reports in Otolaryngology. 2018;3986098. https:// hindawi. com/journals/criot/2018/3986098.
  3. Abdel Razek AAK, Mukherji SK. Imaging of minor salivary glands. Neuroimaging Clin N Am. 2018;28(2):295-302.
  4. Seethala RR. Salivary gland tumors: current concepts and controversies. Surg Pathol Clin. 2017;10(1):155-176.
  5. AlKindi M, Ramalingam S, Hakeem LA, AlSheddi MA. Giant Parotid Pleomorphic Adenoma with Atypical Histological Presentation and Long-

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Term Recurrence-Free Follow-Up after Surgery: A Case Report and Review of the Literature. Case Rep Dent. 2020; 2020:8828775.

  1. Hernandez-Prera JC, Skálová A, Franchi A, et al. Pleomorphic adenoma: the great mimicker of malignancy. Histopathology. 2021;79(3):279-290.
  2. Auclair PL, Ellis GL. Atypical features in salivary gland mixed tumors: their relationship to malignant transformation. Mod Pathol. 1996;9(6):652-7.
  3. Moore BA, Burkey BB, Netterville JL, Butcher RB, Amedee RG. Surgical management of minor salivary gland neoplasms of the palate. Ochsner J. 2008;8(4):172-80.