Solitary Fibrous Tumor of Nasal Cavity:A Case Report

Document Type : Case Report

Authors

Department of Otorhinolaryngology, Christian medical college ,Vellore ,Tamil Nadu, India.

Abstract

Introduction:
Solitary fibrous tumours (SFTs) of the nose and paranasal sinuses are extremely rare.These were originally described as neoplasms of the pleura originating from spindle cells. It is further sub-classified as a benign type of mesothelial tumour. Its occurrence in many extra pleural sites have been reported earlier, mainly in the liver, parapharyngeal space, sublingual glands, tongue, parotid gland, thyroid, periorbital region, and very occasionally in the nose and  paranasal sinus area.
 
Case Report:
A 28-year-old man with a 6 month history of persistent progressive left nasal obstruction and watering of the left eye is reported. Further imaging by CT and MRI revealed a large, left-sided, highly vascular, nasal cavity mass (Fig 1,2,3,4) pushing laterally on the medial wall of the maxilla. The patient underwent a lateral rhinotomy, which proceeded with the excision of the mass. Histopathological analysis of the specimen was consistent with SFT.
 
Conclusion: 
This case is reported to develop insights regarding diagnosis and management of such rare tumours.

Keywords

Main Subjects


1. STOUT AP, HIMADI GM. Solitary (localized) mesothelioma of the pleura. Ann Surg. 1951 Jan; 133(1):50–64.
2. Dunfee BL, Sakai O, Spiegel JH, Pistey R. Solitary Fibrous Tumor of the Buccal Space. Am J Neuroradiol. 2005 Sep;26(8):2114–6.
3. Morales-Cadena M, Zubiaur FM, Alvarez R, Madrigal J, Zarate-Osorno A. Solitary fibrous tumor of the nasal cavity and paranasal sinuses. Otolaryngol-Head Neck Surg Off J Am Acad Otolaryngol-Head Neck Surg. 2006 Dec; 135(6): 980–2.
4. Briselli M, Mark EJ, Dickersin GR. Solitary fibrous tumors of the pleura: eight new cases 7nd review of 360 cases in the literature. Cancer. 1981 Jun; 47(11):2678–89.
5. England DM, Hochholzer L, McCarthy MJ. Localized benign and malignant fibrous tumors of the pleura. A clinicopathologic review of 223 cases. Am J Surg Pathol. 1989 Aug;13(8):640–58.
6. De Perrot M, Fischer S, Bründler M-A, Sekine Y, Keshavjee S. Solitary fibrous tumors of the pleura. Ann Thorac Surg. 2002 Jul;74(1):285–93.
7. Dorfman DM, To K, Dickersin GR, Rosenberg AE, Pilch BZ. Solitary fibrous tumor of the orbit. Am J Surg Pathol. 1994 Mar;18(3):281–7.
8. Hicks DL, Moe KS. Nasal solitary fibrous tumor arising from the anterior cranial fossa. Skull Base Off J North Am Skull Base Soc Al. 2004 Nov; 14(4):203–7.
 9. Brunnemann RB, Ro JY, Ordonez NG, Mooney J, El-Naggar AK, Ayala AG. Extrapleural solitary fibrous tumor: a clinicopathologic study of 24 cases. Mod Pathol Off J United States Can Acad Pathol Inc. 1999 Nov;12(11):1034–42.
10. Zeitler DM, Kanowitz SJ, Har-El G. Malignant solitary fibrous tumor of the nasal cavity. Skull Base Off J North Am Skull Base Soc Al. 2007 Jul; 17(4):239–46.
11. Alobid I, Alós L, Blanch JL, Benítez P, Bernal-Sprekelsen M, Mullol J. Solitary fibrous tumour of the nasal cavity and paranasal sinuses. Acta Otolaryngol (Stockh). 2003 Jan;123(1):71–4.
12. Yang BT, Song ZL, Wang YZ, Dong JY, Wang ZC. Solitary fibrous tumor of the sinonasal cavity: CT and MR imaging findings. AJNR Am J Neuroradiol. 2013 Jul; 34(6):1248–51.
13. Kim TA, Brunberg JA, Pearson JP, Ross DA. Solitary fibrous tumor of the paranasal sinuses: CT and MR appearance. AJNR Am J Neuroradiol. 1996 Oct; 17(9):1767–72.
14. Witkin GB, Rosai J. Solitary fibrous tumor of the upper respiratory tract. A report of six cases. Am J Surg Pathol. 1991 Sep; 15(9):842–8.
15. Morimitsu Y, Nakajima M, Hisaoka M, Hashimoto H. Extrapleural solitary fibrous tumor: clinicopathologic study of 17 cases and molecular analysis of the p53 pathway. APMIS Acta Pathol Microbiol Immunol Scand. 2000 Sep;108(9):617–25.
16. Witkin GB, Rosai J. Solitary fibrous tumor of the mediastinum. A report of 14 cases. Am J Surg Pathol. 1989 Jul;13(7):547–57.
 
17. Kessler A, Lapinsky J, Berenholz L, Sarfaty S, Segal S. Solitary fibrous tumor of the nasal cavity. Otolaryngol--Head Neck Surg Off J Am Acad Otolaryngol-Head Neck Surg. 1999 Dec; 121(6): 826–8.
18. Patel SG, Singh B, Polluri A, Bridger PG, Cantu G, Cheesman AD, et al. Craniofacial surgery for malignant skull base tumors: report of an international collaborative study. Cancer. 2003 Sep 15; 98(6):1179–87.
19. Har-El G. Anterior craniofacial resection without facial skin incisions--a review. Otolaryngol--Head Neck Surg Off J Am Acad Otolaryngol-Head Neck Surg. 2004 Jun; 130(6): 780–7.
20. Vallat-Decouvelaere AV, Dry SM, Fletcher CD. Atypical and malignant solitary fibrous tumors in extrathoracic locations: evidence of their comparability to intra-thoracic tumors. Am J Surg Pathol. 1998 Dec; 22(12):1501–11.
21. England DM, Hochholzer L, McCarthy MJ. Localized benign and malignant fibrous tumors of the pleura. A clinicopathologic review of 223 cases. Am J Surg Pathol. 1989 Aug;13(8):640–58.