Otoacoustic Emissions in Sudden Sensorineural Hearing Loss: Changes of Measures with Treatment

Document Type : Original


1 Department of otorhinolaryngology, Guilan University of Medical Sciences, Rasht, Iran

2 Department of biostatistics, Guilan University of Medical Sciences, Rasht, Iran

3 Ear, Nose, Throat, Head and Neck surgery Research Center, Guilan University of Medical Sciences, Rasht, Iran


To identify changes in OAEs parameters in treatment course of idiopathic sudden sensorineural hearing loss (iSSNHL).
Materials and Methods:
In aprospective studyfromAugust 2005 to January 2009, 26 patients with iSSNHL underwent conventional audiometry/tympanometry and two types of OAEs (TEOAEs and DPOAEs) before and after the completion of standard drug therapy.The changes in pre- and post- treatment parameters were compared with each other and with normal-contralateral ears.
In TEOAEs, the mean overall correlation (reproducibility) and the mean overall strength in involved ears were 10.96±23.36 and 0.99±3.45 dB, respectively, before the treatment, which reached 22.88±36.55 and 1.85±5.3, respectively, after the treatment (P>0.05). Significant difference between “correlation score” (average of correlations at 3-4 involved frequencies) before and after treatment was found: 6.52 ±18.19 vs. 21.67±37.8 (P<0.034). The difference between pre- and post-treatmentoverall correlation and correlation score in the “response group” were significant (P<0.031).  In DPOAEs of the involved ears, the mean DP1 level and the DP1 signal-to-noiseratio changes were not significant with the treatment (P>0.05).
Evoked OAEs, especially TEOAEs, are objective, rapid, and sensitive tools in the treatment course of iSSNHL.