CenoDerm vs. Fascia lata for the Prevention of Dorsal Nasal Irregularities in Rhinoplasty

Document Type : Original


1 Otolaryngology Research Center, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

2 Department of Otolaryngology, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

3 Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.


Dorsal nasal irregularity is a complication of rhinoplasty surgery, mostly seen in patients with thin skin. Acellular dermis (CenoDerm) and homologous fascia lata covering the nasal bone cartilage structure have been used to achieve a smooth surface. In this study, we aimed to investigate clinical outcomes using these two materials.
Materials and Methods:
After a standard rhinoplasty procedure, a layer of the acellular dermis or homologous fascia lata was placed in the pocket of the dorsum. Patients were evaluated for clinical outcomes at 3, 6, and 12 months after the procedure.
Forty-two of 68 patients completed the follow-up period. Patient satisfaction was higher in the homologous fascia lata group. Similarly, nasal dorsum inspection and palpation results were better in the homologous fascia lata group compared with the CenoDerm group but was significant in palpation (P=0.00). There was no complete absorption in the homologous fascia lata group 6 months after surgery (P= 0.04 vs. CenoDerm) but no significant difference was observed at 12 months.
Homologous fascia lata is better than acellular dermis in preventing dorsal nasal irregularity after rhinoplasty in thin-skinned patients.


Main Subjects

1. Cologlu H, Uysal A, Tiftikcioglu YO, Oruc M, Kocer U, Coskun E, et al. Comparison of Autogenous Cartilage, Acellular dermis, and Solvent-Dehydrated Pericardium for the Prevention and Correction of Dorsal Nasal Irregularities: An Experimental Study. Aesth Plast Surg. 2012; 36(3):732–41.
2. Lin G, Lawson W. Complications using grafts and implants in rhinoplasty. Operative Techniques in Otolaryngology 2007; 18(4):315–23.
3. Sang Yu M, Sung Park H, Jin Lee H, Ju Jang Y. Histomorphological Changes of Tutoplast-Processed Fascia Lata Grafts in a Rabbit Rhinoplasty Model. Otolaryngology Head and Neck Surgery 2012; 147(2): 239–44.
4. Gryskiewicz JM. Dorsal Augmentation with AlloDerm. Semin Plast Surg 2008; 22(2):90–103.
5. Kissane NA, Itani KM. A decade of ventral incisional hernia repairs with biologic acellular dermal matrix: what have we learned? Plast and Reconstr Surg 2012; 130 (5s-2): 194–202.
6. Janis JE, O’Neill AC. Acellular dermal matrices in abdominal wall reconstruction: a systematic review of the current evidence. Plast Reconstr Surg 2012; 130
(5s-2): 183-93.
7. Sheridan RL, Choucair RJ. Acellular allogenic dermis does not hinder initial engraftment in burn wound resurfacing and reconstruction. J Burn Care Rehabil 1977; 18(6):496–9.
8. Fisher E, Frodel JL. Facial suspension with acellular human dermal allograft. Arch Facial Plast Surg 1999; 1(3):195–9.
9. Tobin HA, Karas ND. Lip augmentation using an alloderm graft. J Oral Maxillofac Surg 1998; 56:
10. Jackson IT, Yavuzer R. AlloDerm for dorsal nasal irregularities. Plast Reconstr Surg 2001;107(2):553–8.
11. Ghoniem GM. Allograft sling material: is it state of the art? Int Uro-gynecol J Pelvic Floor Dysfunct 2000; 11(2):69–70.
12. Sclafani AP, McCormick SA, Cocker R. Biophysical and microscopic analysis of homologous dermal and fascial materials for facial aesthetic and reconstructive uses. Arch Facial Plast Surg 2002;            4:164-71.
13. Gryskiewicz JM. Waste not, want not: The use of AlloDerm in secondary rhinoplasty. Plast Reconstr Surg 2005;116(7):1999–2004.
14. Ju Jang Y, Hwan Wang J, Sinha V, Song HM, Lee BJ. Tutoplast-processed Fascia Lata for dorsal augmentation in rhinoplasty. Otolaryngology–Head and Neck Surgery 2007; 137(1):88–92.
15.  Tarhan E, Cakmak O, Ozdemir BH, Akdogan V, Suren D. Comparison of AlloDerm, fat, fascia, cartilage, and dermal grafts in rabbits. Arch Facial Plast Surg 2008;10(3):187–193.
16. Sajjadian A, Naghshineh N, Rubinstein R. Status of Grafts and Implants in Rhinoplasty: Part II. Homologous Grafts and Allogenic Implants. Plastic and Reconstructive Surgery 2010;125(3):99–109.
17. Lee DW, Lee MC, Roh H, Lee WJ. Multilayered implantation using acellular dermal matrix into nude mice. J Materials Science. Materials in Medicine 2014; 25(12):2669-76.