Results of neuro-endoscopic pituitary surgery in 26 patients with pituitary adenoma

Document Type : Original

Authors

1 Assistant professor of neurosurgery

2 Department of neurosurgery, Sina hospital, Tehran University of Medical Sciences, Iran

3 Associate Professor of Ear, Throat and Nose

4 Professor of neurosurgery - Tehran University of Medical Sciences

Abstract

Introduction: Endoscopic surgery of pituitary adenoma is a rapidly developing surgical procedure in the field of neurosurgery, with known limitations and advantages. The aim of this study was to evaluate the results of this technique for treatment of a group of patients with pituitary adenoma.
Materials and Methods: In the present study, 26 patients with the diagnosis of pituitary adenoma, who were considered for endoscopic operation between 2002-2005 in Sina and Amir Alam hospitals, were included. The following data were registered: age, sex, symptoms of disease, findings of neurological exam, adenoma type (functional versus non-functional), treatment outcome and complications of the procedure and duration of hospital stay.
Results: Twenty six patients (14 male and 11 female) included in the study. Most of them were in the 3-6 decades of life. They included 11 non-functional adenoma, 9 GH-producing adenomas, 3 ACTH secreting adenomas and 3 cases with prolactinomas. Seven patients had complications of the operation (reversible in 6 patients and fatal in 1) and 6 of them had recurrence of the tumor during the 2-year follow up.
Conclusion: Endoscopic surgery is an invaluable method for treatment of pituitary adenoma, and factors such as decreased complications and duration of hospital stay further adds to its popularity.
 

Keywords

References

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Iranian Journal of Otorhinolaryngology
Volume 20, Issue 53 - Serial Number 53
May and June 2008
Pages 139-144

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