Could Neonatal Hypernatremia Dehydration Influence Hearing Status?

Document Type: Original

Authors

1 Neonatal Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.

2 Department of Otorhinolaryngology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.

Abstract

Introduction:
Neonatal hypernatremia dehydration (NHD) is a dangerous condition in neonates, which is accompanied by acute complications (renal failure, cerebral edema, and cerebral hemorrhage) and chronic complications (developmental delay). Children begin learning language from birth, and hearing impairment interferes with this process. We assessed the hearing status of infants with hypernatremia dehydration.
 
Materials and Methods:
In a case-control study in 110 infants presenting at the Ghaem Hospital (Mashhad, Iran) between 2007 and 2011, we examined the incidence of hearing impairment in infants suffering from hypernatremia dehydration (serum sodium >150 mEq/L) in comparison with infants with normal sodium level (serum sodium ≤150 mEq/L).
 
Results:
Three of 110 cases examined in the study group showed a transient hearing impairment. A mean serum sodium level of 173mg/dl was reported among hearing-impaired infants.
 
Conclusion: 
Transient hearing impairment was higher in infants with hypernatremia; although this difference was not significant (P>0.05). Hearing impairment was observed in cases of severe hypernatremia.
 

Keywords


1. Boskabadi H, Maamouri G, Ebrahimi M, Ghayour-Mobarhan M, Esmaeily H, Sahebkar A, et al. Neonatal hypernatremia and dehydration in infants receiving inadequate breastfeeding. Asia Pac J Clin Nutr 2010; 19(3): 301–7.

2. Boskabadi H, Maamouri GH, Mafinejad S. The Effect of Traditional Remedies (Camel's Thorn, Flixweed and Sugar Water) on Idiopathic Neonatal Jaundice. Iran J Pediatr 2011; 21(3): 325–30.

3. Bhat SR, Lewis P, David A, Liza SM. Dehydration and hypernatremia in breast-fed term healthy neonates. Indian J Pediatar 2006; 73: 39–41.

4. Maamouri GH, Mokhtari Amir Majdi N, Boskabadi H, Khalesi H. Evaluation of Auditory Brainstem Response (ABR) in neonatal hyperbilirubinemia. Iranian Journal of Otorhinolaryn- gology 2008; 51(20): 27–32.

5. Billing KR, Kenna MA. Cause of pediatrics sensorineural hearing loss. Arch Otolaryngol Head Neck Surg 1999; 125: 517–21.

6. Perrott S, Dodds L, Vincer MA.  Population-based Study of Prognostic Factors Related to Major Disability in Very Preterm Survivors. Journal of Perinatology 2003; 23: 111–16.

7. Betty Vohr. Hearing Loss in the Newborn Infant in: Fanaroff AA, Martin RJ. Neonatal-Preinatal Medicine (Disease of Fetus & Infants). 9th ed. St Louis: Mosby; 2011: 1049–53.

8. Daneshmandan N. Hearing and Speech in Children. 1st. Ahoan. 1994. 116–21.

9. Gomes SM, Fernandes CA, Ramos H, Fernandes E, Santos M , Nascimento O, et al. Breastfeeding-associated hypernatraemic dehydration. Einstein  2009; 7(2): 206–10.

10. Jarcan A, Tiker F, Nilgun S.  Weight loss and hypernatremia in breast-fed babies frequency in neonate with non-hemolytic jaundice. Pediatric child heath 2005; 41(9): 484–7.

11. Moritz LM, Manole MD, Bogen DL, Ayus JC. Breastfeeding-Associated Hypernatremia: Are We Missing the Diagnosis? Pediatrics 2005; 116(3): 343–7.

12. Boskabadi H, Abdollahi A, Maamouri G, Esmaeili H. Factors Associated with Hypernatremia in Term Infants with Jaundice. IJOGI. 2013; 16(63): 1–7.

13. Shahfarhat A, Mohammad Allah D. Factors Associated with Hypernatremia in Neonates Reffering to Imam Reza Hospital from 1998 to 1999. Medical Journal of Mashhad University of Medical Sciences; 2002(75): 117–22.

14. Morris-Jones PH, Houston IB, Evans RC. Prognosis of The Neurological Complications Of Acute Hypernatræmia. Lancet 1967; 290(7531): 1385–9.

15. Unal S, ArhanE, KaraN, UncaN, Alifendioglu D. Breast-feeding associated hypernatremia. Pediatric. 2008; 50(1): 29–34.

16. Vassiliou APV, Vlastarakos PV P, Maragoudakis P,  Candiloros D, Nikolopoulos TP Meniere’s disease: Still a mystery disease with difficult differential diagnosis. Ann Indian Acad Neurol 2011; 14(1):           12–18.

17. Barrs DM, Keyser JS, Stallworth C, McElveen JT Jr. Intratympanic Steroid Injections for Intractable Ménière's Disease. The Laryngoscope 2001; 111 (12): 2100–104.