• Home
  • Browse
    • Current Issue
    • By Issue
    • By Author
    • By Subject
    • Author Index
    • Keyword Index
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Editorial Staff
    • Publication Ethics
    • Indexing and Abstracting
    • Related Links
    • FAQ
    • Peer Review Process
    • News
  • Guide for Authors
  • Submit Manuscript
  • Reviewers
  • Contact Us
 
  • Login
  • Register
Home Articles List Article Information
  • Save Records
  • |
  • Printable Version
  • |
  • Recommend
  • |
  • How to cite Export to
    RIS EndNote BibTeX APA MLA Harvard Vancouver
  • |
  • Share Share
    CiteULike Mendeley Facebook Google LinkedIn Twitter Telegram
Iranian Journal of Otorhinolaryngology
Articles in Press
Current Issue
Journal Archive
Volume Volume 30 (2018)
Volume Volume 29 (2017)
Volume Volume 28 (2016)
Volume Volume 27 (2015)
Issue Issue 6
Issue Issue 5
Issue Issue 4
Issue Issue 3
Issue Issue 2
Issue Issue 1
Volume Volume 26 (2014)
Volume Volume 25 (2013)
Volume Volume 24 (2012)
Volume Volume 23 (2011)
Volume Volume 22 (2010)
Iranian Journal of Otorhinolaryngoligy
Rejection Rate 35%
Average time to first decision (days) 41.11

SCImago Journal & Country Rank

Fattahi Masoum, S., Sharifi, N., Taraz Jamshidi, S., Sharifian, A., Rezaee, R. (2015). Primary Small Cell Carcinoma of the Esophagus (PSCEC) Associated with Paraneoplastic Sweating Syndrome: A Case Report and Literature Review. Iranian Journal of Otorhinolaryngology, 27(6), 473-477. doi: 10.22038/ijorl.2015.5475
Seyed Hosein Fattahi Masoum; Noorieh Sharifi; Shirin Taraz Jamshidi; Alireza Sharifian; Reza Rezaee. "Primary Small Cell Carcinoma of the Esophagus (PSCEC) Associated with Paraneoplastic Sweating Syndrome: A Case Report and Literature Review". Iranian Journal of Otorhinolaryngology, 27, 6, 2015, 473-477. doi: 10.22038/ijorl.2015.5475
Fattahi Masoum, S., Sharifi, N., Taraz Jamshidi, S., Sharifian, A., Rezaee, R. (2015). 'Primary Small Cell Carcinoma of the Esophagus (PSCEC) Associated with Paraneoplastic Sweating Syndrome: A Case Report and Literature Review', Iranian Journal of Otorhinolaryngology, 27(6), pp. 473-477. doi: 10.22038/ijorl.2015.5475
Fattahi Masoum, S., Sharifi, N., Taraz Jamshidi, S., Sharifian, A., Rezaee, R. Primary Small Cell Carcinoma of the Esophagus (PSCEC) Associated with Paraneoplastic Sweating Syndrome: A Case Report and Literature Review. Iranian Journal of Otorhinolaryngology, 2015; 27(6): 473-477. doi: 10.22038/ijorl.2015.5475

Primary Small Cell Carcinoma of the Esophagus (PSCEC) Associated with Paraneoplastic Sweating Syndrome: A Case Report and Literature Review

Article 9, Volume 27, Issue 6, November and December 2015, Page 473-477  XML PDF (278 K)
Document Type: Case Report
DOI: 10.22038/ijorl.2015.5475
Authors
Seyed Hosein Fattahi Masoum1; Noorieh Sharifi2; Shirin Taraz Jamshidi 2; Alireza Sharifian3; Reza Rezaee1
1Department of Thoracic Surgery, Mashhad University of Medical Sciences, Mashhad, Iran.
2Solid Tumor Treatment Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3Department of Anesthesiology, Mashhad University of Medical Sciences, Mashhad, Iran.
Abstract
Introduction:
Primary small cell carcinoma of theesophagus (PSCEC) associated with paraneoplastic sweating syndrome is a rare disease characterized with rapid growth rate, metastasis at the time of diagnosis, and poor prognosis. The lung is the most common site for small cell carcinoma but this malignancy includes 0.1% to 1% of all gastrointestinal and 0.8% to 2.7% of esophageal malignancies. So far more than 200 cases of PSCEC have been reported in literature.
 
Case Report:
The patient is a 54-year-old female from the Golestan province who presented with dysphagia, 19 kg-weight loss (from 105 kgs to 86 kgs), and excessive sweating. She was admitted in the thoracic surgery ward, at Ghaem Hospital, in the Mashhad University of Medical Sciences, with a pathological diagnosis of small cell carcinoma. She underwent transhiatal total esophagectomy. Excessive sweating was eradicated after surgery and she was discharged after 13 days without any complication. She received chemotherapy and at her 5-year follow up, she showed no recurrence or metastasis.
 
Conclusion:
PSCEC usually requires chemotherapy with or without surgery. A favorable outcome, with total resection of the lesion combined with chemotherapy, was obtained. However, due to the rarity of the disease there is no definitive choice of treatment.
Keywords
Chemotherapy; Paraneoplastic syndrome; Prognosis; Small cell carcinoma
Main Subjects
Gastroenterology; General Surgery; Head and Neck Surgery
References
1. Brenner B, Tang LH, Shia J, Klimstra DS, Kelsen DP. Small cell carcinomas of the gastrointestinal tract: clinicopathological features and treatment approach. Seminars in oncology. 2007 Feb;34(1):43-50. PubMed PMID: 17270665. Epub 2007/02/03. eng.

2. Casas F, Ferrer F, Farrus B, Casals J, Biete A. Primary small cell carcinoma of the esophagus: a review of the literature with emphasis on therapy and prognosis. Cancer. 1997 Oct 15;80(8):1366-72. PubMed PMID: 9338459. Epub 1997/10/24 21:28. eng.

3. Lv J, Liang J, Wang J, Wang L, He J, Xiao Z, et al. Primary small cell carcinoma of the esophagus. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2008 Dec;3(12):1460-5. PubMed PMID: 19057273. Epub 2008/12/06. eng.

4. McKeown F. Oat-cell carcinoma of the oesophagus. The Journal of pathology and bacteriology. 1952 Oct;64(4):889-91. PubMed PMID: 13000600. Epub 1952/10/01. eng.

5. Beyer KL, Marshall JB, Diaz-Arias AA, Loy TS. Primary small-cell carcinoma of the esophagus. Report of 11 cases and review of the literature. Journal of clinical gastroenterology. 1991 Apr;13(2):135-41. PubMed PMID: 1851772. Epub 1991/04/01. eng.

6. Ku GY, Minsky BD, Rusch VW, Bains M, Kelsen DP, Ilson DH. Small-cell carcinoma of the esophagus and gastroesophageal junction: review of the Memorial Sloan-Kettering experience. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 2008 Mar;19(3):533-7. PubMed PMID: 17947223. Epub 2007/10/20. eng.

7. Madroszyk A, Egreteau J, Martin L, Queneau PE, Bosset JF, Merrouche Y. Small-cell carcinoma of the esophagus: report of three cases and review of the literature with emphasis on therapy. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 2001 Sep;12(9):1321-5. PubMed PMID: 11697847. Epub 2001/11/08. eng.

8. Medgyesy CD, Wolff RA, Putnam JB, Jr., Ajani JA. Small cell carcinoma of the esophagus: the University of Texas M. D. Anderson Cancer Center experience and literature review. Cancer. 2000 Jan 15;88(2):262-7. PubMed PMID: 10640955. Epub 2000/01/21. eng.

9. Shimoda T, Koizumi W, Tanabe S, Higuchi K, Sasaki T, Nakayama N, et al. Small-cell carcinoma of the esophagus associated with a paraneoplastic neurological syndrome: a case report documenting a complete response. Japanese journal of clinical oncology. 2006 Feb;36(2):109-12. PubMed PMID: 16517835. Epub 2006/03/07. eng.

10. Sun KL, He J, Cheng GY, Chai LX. Management of primary small cell carcinoma of the esophagus. Chinese medical journal. 2007 Mar 5;120(5):355-8. PubMed PMID: 17376302. Epub 2007/03/23. eng.

11. McFadden DW, Rudnicki M, Talamini MA. Primary small cell carcinoma of the esophagus. The Annals of thoracic surgery. 1989 Mar;47(3):477-80. PubMed PMID: 2539065. Epub 1989/03/01. eng.

 

12. Nemoto K, Zhao HJ, Goto T, Ogawa Y, Takai Y, Matsushita H, et al. Radiation therapy for limited-stage small-cell esophageal cancer. American journal of clinical oncology. 2002 Aug;25(4):404-7. PubMed PMID: 12151974. Epub 2002/08/02. eng.

13. Yun JP, Zhang MF, Hou JH, Tian QH, Fu J, Liang XM, et al. Primary small cell carcinoma of the esophagus: clinicopathological and immunohistochemical features of 21 cases. BMC cancer. 2007;7:38. PubMed PMID: 17335582. Pubmed Central PMCID: PMC1829164. Epub 2007/03/06. eng.

14. Nevarez A, Saftoiu A, Bhutani MS. Primary Small Cell Carcinoma of the Esophagus: Clinico- pathological Features and Therapeutic Options. Current health sciences journal. 2011 Jan;37(1):31-4. PubMed PMID: 24778832. Pubmed Central PMCID: PMC3994671. Epub 2011/01/01. eng.

15. Rashtak S, Pittelkow MR. Skin involvement in systemic autoimmune diseases. Current directions in autoimmunity. 2008;10:344-58. PubMed PMID: 18460895. Epub 2008/05/08. eng.

16. Situ D, Lin Y, Long H, Zhang L, Lin P, Zheng Y, et al. Surgical treatment for limited-stage primary small cell cancer of the esophagus. The Annals of thoracic surgery. 2013 Mar;95(3):1057-62. PubMed PMID: 23333059. Epub 2013/01/22. eng.

17. Gollard R, Ellis C, VanderHarten C. Small cell/neuroendocrine tumors of the esophagus: presentation of two cases and review of the literature. Tumori. 2010 Sep-Oct;96(5):780-3. PubMed PMID: 21302629. Epub 2011/02/10. eng.

Statistics
Article View: 1,602
PDF Download: 1,117
Home | Glossary | News | Aims and Scope | Sitemap
Top Top

Journal Management System. Designed by sinaweb.