Herpes Zoster Induced Alveolar Bone Necrosis in Immunocompromised Patients; Two Case Reports

Document Type: Case Report


1 Oral and Maxillofacial Disease Research Center, Dental Faculty, Mashhad University of Medical Science, Mashhad, Iran.

2 Department of Oral and Maxillofacial Surgery, Dental Faculty, Mashhad University of Medical Science, Mashhad, Iran.

3 Department of Oral and Maxillofacial Medicine, Dental Faculty, Mashhad University of Medical Science, Mashhad, Iran.

4 Dentistry Research Center, Dental Faculty, Golestan University of Medical Science, Gorgan, Iran.


Herpes zoster Infection (HZI) is a viral disease with painful skin rashes and blisters in a limited area on one side of the body, often in a strip. Osteonecrosis with spontaneous exfoliation of teeth in association with HZI of the mandibular nerve is a rare phenomenon. In this report, such an unusual complication of HZI is presented.
Case Report:
The clinical course of a 53-year-old woman and a 54-year-old man with HZI associated with alveolar bone necrosis and tooth exfoliation were reviewed in order to develop a patient profile for this rare combination of physical findings.
In immunocompromised patients, the clinicians should consider HZI as a possible cause of tooth mobility, exfoliation, and alveolar osteonecrosis, which needs early intervention to prevent secondary complications.


Main Subjects

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